Treatment
Bupivacaine clinical trials
We’re tracking 202 recruiting studies that include Bupivacaine, each written for real people, not researchers, below.
Recruiting studies
- NCT07558642Recruiting
Nerve Block to Reduce Confusion in Older ICU Patients
This study tests whether a nerve-blocking injection (stellate ganglion block) can reduce confusion and help restore normal sleep-wake cycles in older adults staying in the intensive care unit. Researchers hope this treatment may help patients recover faster and feel more alert.
Antalya, MuratpaşaAges 65–99 - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06719180RecruitingPhase 4
Pain relief after a hysterectomy
This study tests if numbing the top of the vagina (vaginal cuff) with a local anesthetic can reduce the need for pain medicine after a hysterectomy done by laparoscopy (small cuts in the belly). If you are having this surgery for a non-cancerous condition or cancer, you may be able to join.
Flushing, New YorkAges 18 years+ - NCT06759116Recruiting
Comparing two pain medicines for knee surgery recovery
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
El SharkiaAges 21–85 - NCT07468604RecruitingPhase 4
Nerve block for long COVID symptoms
This study tests a procedure called a cervicothoracic sympathetic block (a nerve block in the neck) to see if it helps with long-term symptoms after COVID-19, like dizziness, sweating, or stomach problems. It's for people whose symptoms have lasted at least 3 months and who have not tried this treatment before.
Toronto, OntarioAges 18 years+ - NCT07440576Recruiting
Numbing shot for pain after prolapse surgery
This trial tests if a numbing injection in the cervix area can reduce pain after minimally invasive prolapse surgery. If you're having this surgery, the study may help determine if the shot makes recovery more comfortable.
Istanbul, IstanbulAges 18 years+ - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT07412522Recruiting
Pain relief injection for minimally invasive heart bypass surgery
This study tests whether a special injection between the ribs can reduce pain after minimally invasive heart bypass surgery. The injection is given before surgery to help with pain control and may reduce the need for strong pain medicines.
IstanbulAges 18–75 - NCT07374562Recruiting
Nerve block for Long COVID symptoms
This study tests a nerve block injection (called a stellate ganglion block) to see if it can help relieve ongoing symptoms of Long COVID, especially breathing problems. It is for people who have had COVID-19 symptoms for at least 3 months.
Trois-Rivières, QuebecAges 18 years+ - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT07348016Recruiting
Platelet-rich plasma and steroid injection for shoulder surgery
This trial tests if adding a combination of platelet-rich plasma (a concentrate from your own blood that may help healing) and a steroid (to reduce inflammation) during arthroscopic surgery improves recovery for people with a torn rotator cuff and a stiff, stuck shoulder.
Nanchang, JiangxiAges 18–70 - NCT07322445Recruiting
Study of neck and shoulder pain with special MRI
This study uses special MRI scans to look at muscles and nerves in people with long-term neck or shoulder pain caused by trigger points (tender spots in muscles). The goal is to understand what happens in the body with this type of pain—so doctors can find better ways to treat it.
St Louis, MissouriAges 18–80 - NCT07322419RecruitingPhase 4
Blood pressure medicines during c-section: norepinephrine vs ephedrine
This trial compares two medicines, norepinephrine and ephedrine, to see which one works better at keeping blood pressure stable during a planned C-section under spinal anesthesia. It will help doctors choose the safest option for mothers and babies.
Al Mansurah, Dakahlia GovernorateAges 19–40 - NCT07280195Enrolling by invitationPhase 4
Comparing pain relief after shoulder replacement
This study compares two ways to manage pain after shoulder replacement surgery: a long-acting numbing medicine (ZYNRELEF) versus a temporary nerve block catheter. It aims to see which provides better pain control and recovery.
St Louis, MissouriAges 18 years+ - NCT07274215Recruiting
Nerve block injection for pain and nausea after sleeve gastrectomy
This study tests a special numbing injection (called a paragastric block) to see if it reduces pain and nausea after sleeve gastrectomy surgery. If you are having this weight-loss surgery, the injection might help you feel better and recover more comfortably.
IstanbulAges 18–65 - NCT06545409Recruiting
Nerve block for pain relief in robotic thymus surgery
This trial tests a nerve block to reduce pain after robotic thymus surgery. It may help patients with thymus growths or cysts have less pain and use fewer painkillers after their operation.
RomeAges 18 years+ - NCT07264699Recruiting
Guided nerve block for hernia repair pain control
This trial tests whether a visually guided nerve block (TAP block) during laparoscopic hernia repair reduces pain and improves recovery. If you are having planned hernia surgery, this study may help you experience less pain after the procedure.
Olsztyn, Warmisko-mazurskieAges 18–80 - NCT06904703Recruiting
Nerve blocks for older adults having hip replacement surgery
This trial tests two types of nerve blocks to see which one works better for pain control in older adults undergoing total hip replacement. A nerve block is a shot of anesthetic near a nerve to numb a specific area, and the goal is to help you feel less pain after surgery.
TantaAges 75 years+ - NCT07216820Recruiting
Nerve blocks for shoulder surgery in obesity
This study compares two types of nerve blocks for shoulder surgery in people with obesity. It tests whether a block that spares the phrenic nerve (which helps you breathe) can keep your breathing strength stronger after surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT07176533Recruiting
Nerve block for pain after tonsil surgery in kids
This study tests a nerve block (a numbing injection near the cheekbone) to reduce pain after tonsil surgery in children with sleep apnea. It might help them have less pain and recover more comfortably.
London, OntarioAges 3–9 - NCT07178262RecruitingPhase 4
Nerve block to reduce pain medicine after hysterectomy
This study tests whether a nerve block (an injection near the spine) can help reduce the amount of strong pain medicine you need after a hysterectomy. The goal is to see if it leads to fewer side effects and a smoother recovery.
Islamabad, FederalAges 16–80 - NCT07146685RecruitingPhase 4
Testing different strengths of numbing medicine for shoulder replacement
This study compares two different strengths of local anesthetic used in a nerve block for shoulder replacement surgery. The goal is to see if one strength helps reduce pain that can come back as the block wears off.
Charlottesville, VirginiaAges 18 years+ - NCT06456255RecruitingPhase 2/Phase 3
Numbing injection study for first-time sinus surgery
This study tests a numbing medication (bupivacaine with epinephrine) injected during your first sinus surgery to see if it helps reduce pain after the procedure. It may be an option if you have not had sinus surgery before and are generally healthy.
Vancouver, British ColumbiaAges 19 years+ - NCT07091123RecruitingPhase 4
Comparing two treatments for chronic back pain after surgery
This study compares two treatments for long-term back pain after surgery: a spinal cord stimulator (a device that sends mild electrical pulses to your spine) and a pump that delivers pain medicine directly to your spinal fluid. It will look at which treatment you prefer and how well it works over time.
Cleveland, OhioAges 30 years+
Common questions
- Are there clinical trials studying Bupivacaine?
- Yes. Clin2 currently lists 202 recruiting studies that include Bupivacaine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Bupivacaine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Bupivacaine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Bupivacaine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.