Treatment
Comparator clinical trials
We’re tracking 1,754 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT05377034RecruitingPhase 2
Y-90 and immunotherapy vs Y-90 plus placebo for liver cancer
This phase 2 study tests whether adding immunotherapy drugs (atezolizumab and bevacizumab) after Y-90 treatment works better and is safe compared with Y-90 followed by placebo. It is for people with liver cancer that has not spread outside the liver but is difficult to treat.
BeijingAges 21–99 - NCT05380050Recruiting
Telehealth vs in-person skills training for brain injury and PTSD
This study compares a combined skills program delivered by video/phone (telehealth) versus meeting in person. It aims to improve attention and coping skills for veterans who have both mild brain injury and PTSD.
Gainesville, FloridaAges 30–55 - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05402072RecruitingPhase 1
Compare a collagen implant vs microfracture for hip cartilage damage
This Phase 1 study tests whether an “AMIC” collagen-based treatment works better or safely than the standard microfracture procedure for a specific kind of hip cartilage injury. If you have ongoing hip pain from a cartilage defect (not arthritis), you may be able to join and receive one of these surgical treatments along with a study rehab plan.
Hamilton, OntarioAges 18–55 - NCT05408845RecruitingPhase 2
Study drug vs standard care for HER2 salivary gland cancer
This Phase 2 trial tests how well ado-trastuzumab emtansine (and compares to two standard treatment options) works for salivary gland cancers that are HER2-positive or HER2-low. It aims to see whether the study drug can control cancer better and with acceptable side effects.
Birmingham, AlabamaAges 18 years+ - NCT05413616Recruiting
Personalized nutrition and activity therapy for older hospital patients
This study tests whether a tailored nutrition plan plus a step-by-step exercise program can improve physical strength and performance in older adults in the hospital. It compares these interventions to the usual hospital care you would normally get.
Nijmegen, GelderlandAges 65 years+ - NCT05424354RecruitingPhase 4
Test powder dressing vs usual care for recent burn wounds
This study compares a transforming powder dressing to the standard dressing for partial-thickness burn wounds. It aims to see whether the powder dressing helps wounds heal better and safely when used soon after the burn.
Orange, CaliforniaAges 18–65 - NCT05432466RecruitingPhase 3
Celiprolol vs placebo for vascular Ehlers-Danlos heart vessel fragility
This Phase 3 study compares celiprolol (a blood vessel–related medicine) versus placebo to see which better reduces vascular risks in people with vascular Ehlers-Danlos syndrome. It requires confirmed COL3A1 genetic findings and specific imaging before starting.
Culver City, CaliforniaAges 15–64 - NCT05436054RecruitingPhase 4
Plenvu vs Picoprep bowel prep for colonoscopy
This study compares two bowel-cleansing products (Plenvu and Picoprep) to see which works better and is easier to tolerate before a colonoscopy. It may help patients by improving the chance of a clear exam and reducing unpleasant side effects.
Aalborg, North JutlandAges 18 years+ - NCT05469659RecruitingPhase 2
Test drug to slow kidney damage in type 2 diabetes
This Phase 2 study compares tofogliflozin to metformin to see how well they reduce urine albumin levels (a marker of kidney stress) in people with diabetic kidney disease. You might benefit if your type 2 diabetes is affecting your kidneys despite standard blood-pressure medicines.
Matsumoto, NaganoAges 20 years+ - NCT05470127Recruiting
Testing a new prostate biopsy needle against the usual one
This study compares a new prostate biopsy system/needle with the standard biopsy needle during your scheduled prostate biopsy. It looks at how well the procedure collects tissue for diagnosis and how the tissue samples compare.
Cartersville, GeorgiaAges 18–90 - NCT05472792RecruitingPhase 2
Testing breast radiation after lumpectomy with or without hormone pills
This Phase 2 trial compares different “after-surgery” treatment plans for certain older women with hormone-sensitive early breast cancer. It looks at whether a standard hormone-pills approach or a faster, smaller-area radiation approach (given after lumpectomy) works best to prevent cancer coming back.
Chapel Hill, North CarolinaAges 65 years+ - NCT05477576RecruitingPhase 3
Lu-177–treated NET patients: new drug versus standard care
This Phase 3 trial tests RYZ101 versus standard of care in people with inoperable, well-differentiated SSTR-positive GI or pancreas neuroendocrine tumors (NETs) that keep growing after Lu-177 SSA. It may help by improving tumor control after your prior targeted radiation treatment.
Phoenix, ArizonaAges 18 years+ - NCT05480982Recruiting
Cognitive functional therapy versus Pilates for low back pain
This study compares two exercise-based approaches—cognitive functional therapy and Pilates—to help reduce chronic low back pain in older adults. It may help by improving how you move and manage pain, not just stretching muscles.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT05486546Recruiting
Compare two LASIK mapping methods for myopia and astigmatism
This trial compares two ways of mapping your eye to guide LASIK surgery for people with nearsightedness and mild astigmatism. It looks at how well vision (especially best-corrected vision) does after surgery one month later.
Bozeman, MontanaAges 21–38 - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT05507723Recruiting
Smartphone-guided tight gout control vs usual care
This study tests whether a “tighter” gout treatment plan guided through a smartphone app can reduce gout flare-ups compared with usual care. It may help people whose uric acid levels are still high despite treatment.
EdinburghAges 18 years+ - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05534724Recruiting
Compare early vs partial weight bearing after bunion surgery
This study compares whether it’s safer to put weight on your foot early versus only partly after bunion surgery. It may help your care team choose the best recovery plan for healing and comfort.
LuganoAges 18–85 - NCT05536011Recruiting
Pregnancy registry for women taking WAKIX (pitolisant)
This registry collects information about pregnancy outcomes in women who took WAKIX (pitolisant) or a similar comparison medicine during pregnancy. It helps doctors understand the safety and effects of these medicines in pregnancy.
Morrisville, North CarolinaAges Any age - NCT05540704Recruiting
Therapy support for eating problems in type 1 diabetes
This study compares three groups: Acceptance and Commitment Therapy, standard supportive diabetes counseling, or a waitlist. It aims to reduce binge eating and harmful weight-control behaviors, including insulin withholding, in people with type 1 diabetes.
Durham, North CarolinaAges 16–50 - NCT05561387RecruitingPhase 3
Drug combinations for newly diagnosed myeloma without transplant
This study compares different combinations of medicines for people newly diagnosed with multiple myeloma who cannot safely get a stem cell transplant. It aims to find which drug plan works best and is tolerable for people with “frail” or “intermediate fit” health.
Anchorage, AlaskaAges Any age - NCT05561907Recruiting
Endoscopic vs. surgical bypass for stomach blockage from cancer
This trial compares two ways to bypass a blockage in your stomach caused by cancer near the pancreas or duodenum. Both approaches create a new connection so food can pass through, but one uses a camera-guided tube (endoscopic) and the other is surgical. The study will see which works better for your symptoms and quality of life.
New Brunswick, New JerseyAges 18 years+ - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,754 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.