Treatment
Comparator clinical trials
We’re tracking 1,754 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT05161091Recruiting
Orosol® mouth treatment for chemo or radiation mouth sores
This trial tests whether Orosol® can reduce mouth sores caused by chemotherapy or radiation. If you have moderate to severe mouth sores from these treatments, it may help improve comfort and healing.
Clermont-FerrandAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT05197192RecruitingPhase 3
New treatment for high-risk CLL using two medicines plus chemo-free pills
This trial tests whether adding acalabrutinib to obinutuzumab plus venetoclax works better than the standard combo (obinutuzumab plus venetoclax) for people with untreated, high-risk CLL. It’s designed to see if the stronger mix can improve control of the leukemia with an acceptable safety profile.
Bad SaarowAges 18–120 - NCT05203003Recruiting
Testing whether measurable cancer leftovers predict outcomes
This study looks at whether small leftover signs of multiple myeloma in blood or bone marrow (called measurable residual disease, or MRD) can predict how well treatment works. It involves people already taking study treatment in a larger trial and checks results about two years later to see who benefits most.
ParisAges 18 years+ - NCT05215353RecruitingPhase 4
Music therapy or talk therapy for anxiety after cancer
This study compares music therapy and cognitive behavioral therapy (CBT) to see which better reduces anxiety in people who have had cancer. You may be randomly assigned to one of the two therapy programs and will join sessions by video call.
Miami, FloridaAges 18 years+ - NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Scottsdale, ArizonaAges 18 years+ - NCT05226637Recruiting
Shockwave plus botox-like treatment versus standard care for arm spasticity
This study tests whether adding shockwave treatment to botulinum toxin type A (a botox-like injection) improves outcomes for people with stiff, tight upper-arm muscles after brain injury, stroke, or cerebral palsy. It also compares this to standard botulinum toxin care alone.
Edmonton, AlbertaAges 18–99 - NCT05232604Recruiting
Exercise vs local pain exercises for jaw and neck pain
This study compares two types of treatment: aerobic exercise versus exercises aimed at the painful jaw/neck area. It may help people with long-term jaw and neck pain by testing which approach improves pain and function.
Osnabrück, Lower SaxonyAges 18–60 - NCT05237258Recruiting
Compare palliative care approaches for people with high-risk AML
This study tests a specialized (targeted) palliative care program versus usual oncology care for people hospitalized with high-risk acute myeloid leukemia (AML). The goal is to see if this palliative approach improves comfort, support, and care planning during intensive treatment.
Birmingham, AlabamaAges 18–120 - NCT05245656RecruitingPhase 2
Rituximab plus chemo plans for older mantle cell lymphoma
This Phase 2 trial studies whether an “extra chemo” schedule (adding cytarabine) can work better than a standard rituximab-bendamustine plan in older people with mantle cell lymphoma. It compares two treatment sequences to see which one helps patients live longer and respond better with acceptable safety.
Seoul, Gangnam-GuAges 60 years+ - NCT05255471RecruitingPhase 3
Olaparib after surgery for recurrent ovarian cancer
This trial tests whether olaparib (a pill cancer medicine) works better than standard platinum chemotherapy after a second surgery for recurrent ovarian cancer. It’s for people whose cancer returned after initial PARP-inhibitor (PARPi) maintenance and aims to see if treatment can control the cancer for longer with acceptable side effects.
NaplesAges 18 years+ - NCT05271240RecruitingPhase 3
Targeted brain-artery drug added to standard treatment for new GBM
This Phase 3 trial tests whether delivering a cancer drug directly into brain blood vessels, along with standard radiation and temozolomide, works better than standard treatment alone in newly diagnosed glioblastoma (GBM). The goal is to improve control of the tumor while comparing side effects between the two approaches.
New York, New YorkAges 18 years+ - NCT05275335Recruiting
Study how germs in burn wounds are best identified
This study compares two ways of finding germs (microbes) in burn wounds: traditional tissue swabs/cultures versus a newer DNA-based method. It may help improve how clinicians understand burn infections and tailor care.
Galveston, TexasAges 18–100 - NCT05282108Recruiting
Generic imatinib vs Glivec for newly diagnosed CML
This trial studies whether a generic version of imatinib (Carcemia®) works as well and is as safe as Glivec® in real-life care for people newly diagnosed with chronic phase chronic myeloid leukemia (CML). It may help confirm that the generic option is effective for controlling the disease.
CairoAges 18 years+ - NCT05292742RecruitingPhase 2
Continue targeted breast cancer therapy or switch to a new combo
This Phase 2 study compares two treatment plans after breast surgery when cancer did not fully disappear before surgery. It tests whether adding trastuzumab, pyrotinib, and capecitabine works better than continuing the original targeted therapy.
Fuzhou, FujianAges 18–75 - NCT05297734Recruiting
Study compares two cancer support care plans
This study tests two different ways of providing supportive care for adults with cancer to see which one works better. It may help improve comfort, support, and care coordination during treatment.
Birmingham, AlabamaAges 18 years+ - NCT05301543Recruiting
Program to improve long-term insomnia symptoms
This study tests a behavioral (non-medication) program to help people with chronic insomnia sleep better. It may help if you regularly use sleep medications but still struggle with staying asleep or falling asleep.
Philadelphia, PennsylvaniaAges 55–85 - NCT05303337Recruiting
Study of gut and HIV changes after switching to long-acting shots
This trial compares how HIV “reservoirs,” inflammation, and the gut microbiome change when people switch from daily HIV pills to long-acting injectable treatment. It may help you and your team understand what to expect with the switch and how your body responds.
MarseilleAges 18 years+ - NCT05313945Recruiting
Compare comfort after passive vs active catheter removal
This study tests which method of removing an in-place urinary (bladder) catheter is more satisfying and comfortable for patients after certain urologic procedures. If you qualify, you may be randomly assigned to one of two removal approaches and asked about your experience.
GrenobleAges 18 years+ - NCT05344612Recruiting
Testing CT scan first to guide treatment for chest pain
This trial studies whether doing a special heart scan (CTCA) right away can better guide treatment for people with chest pain who might have coronary artery disease. It compares this “scan-first” strategy to standard care to see which approach leads to better outcomes and fewer unnecessary procedures.
Amsterdam, North HollandAges 18 years+ - NCT05344651Recruiting
Compare two glaucoma drainage devices and cornea effects
This study compares two surgical drainage devices used for glaucoma and looks at how they affect the clear front window of the eye (the cornea). It may help you understand which device is gentler on the cornea over time.
RotterdamAges 18–100 - NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT05348564Recruiting
Family genetic screening methods for heart rhythm risk
This study compares two ways to find relatives who may carry a specific inherited genetic change. It may help your family learn faster who should get follow-up testing and care.
Lancaster, PennsylvaniaAges 18 years+ - NCT05366452Recruiting
Early heart pump implant for shock after a heart attack
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Marseille, Bouche DU RhoneAges 18–80
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,754 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.