Treatment
Estrogen clinical trials
We’re tracking 78 recruiting studies that include Estrogen, each written for real people, not researchers, below.
Recruiting studies
- NCT07649356Recruiting
Estrogen and Muscle Function in Menopausal Women
This study compares how estrogen affects muscle strength and fitness in women before and after menopause. It aims to understand how hormonal changes during menopause impact physical health and may help researchers develop better support for women during this life stage.
AarhusAges 47 years+ - NCT07617454Recruiting
Estrogen and Muscle Gain in Postmenopausal Women
This study looks at how estrogen affects muscle growth when postmenopausal women exercise for 12 weeks. Researchers want to understand whether estrogen plays a role in helping muscles develop stronger during strength training.
Aarhus, JutlandAges 40 years+ - NCT06713512Recruiting
Estrogen and its effect on lung tissue in obstructive lung disease
This study looks at how the hormone estrogen affects the lungs of people with asthma or COPD. It will help researchers understand why these diseases may be different in women.
LondonAges 18–99 - NCT06357442Recruiting
Comparing progesterone methods for young people on estrogen therapy
This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
Aurora, ColoradoAges 12–25 - NCT07467772RecruitingPhase 2
Elacestrant for estrogen receptor-positive uterine sarcoma
This trial tests whether elacestrant, a drug that blocks estrogen, can help people with certain types of uterine sarcoma that have strong estrogen receptors. It may slow or stop cancer growth in tumors that rely on estrogen.
Boston, MassachusettsAges 18 years+ - NCT07400419Recruiting
Resistance exercise for transgender individuals starting estrogen therapy
This study looks at whether doing resistance training (like lifting weights) can help people who are starting estrogen-based hormone therapy as part of their gender transition. It focuses on how exercise might affect body strength and health during this time.
Boston, MassachusettsAges 18 years+ - NCT05020860RecruitingPhase 2
Study how early breast cancer responds on imaging and under a microscope
This Phase 2 study looks at how well early breast cancer shrinks with treatment and how that matches with what doctors find after surgery under the microscope. The goal is to learn better ways to predict and assess treatment success.
Houston, TexasAges 18 years+ - NCT07361263Recruiting
Study of oxytocin response to oral estrogens
This trial looks at how the body's oxytocin level changes after taking estrogen pills. It includes healthy people and those with a condition called AVP-deficiency (a lack of a hormone that controls water balance). The study aims to understand how estrogen affects oxytocin.
BaselAges 18–50 - NCT07340541RecruitingPhase 2
Personalized cancer therapy trial based on tumor markers
This trial tests new treatments that are chosen based on specific markers in your tumor. Researchers want to see if these personalized therapies work better than standard options.
New Haven, ConnecticutAges 18 years+ - NCT07287098RecruitingPhase 2
Imlunestrant for premenopausal women with ER+/HER2- early breast cancer
This trial tests a new hormone-blocking pill (imlunestrant) in premenopausal women with early-stage ER+/HER2- breast cancer. Depending on whether you've had prior hormone therapy, the study will see if this treatment works better than standard options.
Birmingham, AlabamaAges 18 years+ - NCT07275463Enrolling by invitationPhase 2
Study of DB8 imaging in estrogen receptor positive and negative breast cancer
This trial uses a special imaging agent called DB8 to see how it builds up in breast tumors. It compares results between women with estrogen receptor-positive and estrogen receptor-negative cancers to help improve detection.
TomskAges 18–80 - NCT07262138Recruiting
Active monitoring for older women with early breast cancer
This trial studies whether active monitoring (watchful waiting) can be a safe option instead of immediate surgery or other treatments for women 70 and older who have a small, slow-growing type of breast cancer. If you join, you will not have surgery or other treatments right away, but your cancer will be closely watched.
Pittsburgh, PennsylvaniaAges 70 years+ - NCT07268183Recruiting
Estrogen changes and prolactinoma tumor size
This study looks at how changes in estrogen before diagnosis affect the growth of prolactin-secreting pituitary tumors (prolactinomas). The goal is to understand why some tumors are larger than others.
Bron, RhoneAges 18 years+ - NCT07222215RecruitingPhase 2
Capacitabine with or without elacestrant for ER+ breast cancer
This trial tests if adding a new oral targeted therapy (elacestrant) to standard chemotherapy (capecitabine) works better than chemotherapy alone for people with a specific type of advanced breast cancer that is hormone-sensitive (ER-positive) and has stopped responding to hormone therapy.
Boston, MassachusettsAges 18 years+ - NCT07222267RecruitingPhase 1
Study of BG-75202 for advanced solid tumors
This trial tests a new drug called BG-75202, alone or with other drugs, for people with advanced breast cancer or other solid tumors that have stopped responding to standard treatments. It may offer a new option when other treatments have failed.
Birmingham, AlabamaAges 18 years+ - NCT07214532Recruiting
Using a blood test to guide breast cancer therapy
This study tests whether a blood test can help decide when to start additional hormone-blocking therapy for early-stage breast cancer. It aims to see if starting therapy only when the test detects cancer DNA is as effective as giving it to everyone.
Phoenix, ArizonaAges 18 years+ - NCT07160504RecruitingPhase 4
Vaginal estrogen's effect on blood clotting in postmenopausal women
This trial tests if low-dose vaginal estrogen tablets affect blood clotting in postmenopausal women with vaginal atrophy. It includes women both with and without a past blood clot to see if the treatment is safe.
Aarhus NAges 50 years+ - NCT06969326RecruitingPhase 3
Estrogen cream after hysterectomy for transgender men
This study tests whether using a topical estrogen cream after hysterectomy surgery can help transgender men have a better recovery. Participants will be randomly assigned to use the cream or not, and researchers will follow up by text message.
Providence, Rhode IslandAges 18 years+ - NCT07100106RecruitingPhase 1/Phase 2
Study of GDC-4198 alone or with giredestrant for advanced breast cancer
This trial tests a new treatment (GDC-4198) alone or with another drug (giredestrant) compared to a standard combination (abemaciclib and giredestrant) for people with advanced hormone receptor-positive, HER2-negative breast cancer that has progressed after previous treatments.
Huntsville, AlabamaAges 18 years+ - NCT05333328RecruitingPhase 4
Test of ovarian function suppression for low-risk premenopausal node+ breast cancer
This trial studies whether ovarian function suppression (a treatment that lowers hormone production from the ovaries) helps women with hormone-receptor positive, HER2-negative breast cancer that has spread to lymph nodes, but who have a low-risk result on a genomic test. It may help reduce breast cancer recurrence while avoiding more intensive treatment for those who are lower risk.
Seoul, KoreaAges 20–50 - NCT07053982Recruiting
New scan to find endometriosis spots
This trial tests a new type of PET/CT scan that uses a special tracer to find endometriosis lesions. It may help surgeons see exactly where the disease is, which could lead to more complete treatment.
ToulouseAges 18 years+ - NCT07010146RecruitingPhase 2
Estrogen's Effect on Bone Health in FHA
This study tests how estrogen treatment affects bone strength in young women with Functional Hypothalamic Amenorrhea (FHA), a condition where periods stop due to stress, low weight, or over-exercise. Participants who have had very few periods will receive estrogen to see if it improves bone density.
Charlottesville, VirginiaAges 14–30 - NCT06905210RecruitingPhase 3
New hormonal pill for moderate acne in women
This trial tests a new combination hormonal pill (a progestogen and low-dose estrogen) to treat moderate acne in women. It may be an option if you have not had success with other acne treatments.
Itapevi, São PauloAges 14–45 - NCT06873971Recruiting
Laser plus vaginal estrogen for menopause symptoms
This trial tests if combining a special laser treatment with a vaginal estrogen cream can help relieve menopause symptoms like vaginal dryness, burning, and pain during sex. It may be a good option for women who have not used hormone therapy recently.
São Paulo, São PauloAges 45–70
Common questions
- Are there clinical trials studying Estrogen?
- Yes. Clin2 currently lists 78 recruiting studies that include Estrogen, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Estrogen trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Estrogen an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Estrogen or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.