Treatment
Midazolam clinical trials
We’re tracking 72 recruiting studies that include Midazolam, each written for real people, not researchers, below.
Recruiting studies
- NCT07565116Recruiting
Numbing Nose Spray vs. Calming Liquid Before Pediatric Surgery
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
Diyarbakır, Outside of the USAges 2–10 - NCT07608705RecruitingPhase 1
How HRS-1301 Affects Body Processing of Two Common Drugs
This study tests how a new drug called HRS-1301 changes the way your body processes two common medications: midazolam (a sedative) and atorvastatin (a cholesterol drug). Healthy volunteers help researchers understand drug safety and interactions before testing in patients with illness.
Jinan, ShandongAges 18–55 - NCT07426757RecruitingPhase 1
A study of PF-07994525 for advanced multiple myeloma
This trial tests an experimental drug, PF-07994525, for people with advanced multiple myeloma that has not responded to or could not tolerate at least 3 prior treatments. The goal is to see if it can help control the cancer.
Coral Gables, FloridaAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT05602636RecruitingPhase 4
Nerve-block pain options during forearm surgery
This trial compares three ways to control pain during forearm surgery: different nerve blocks versus using a PCA pain pump. It may help find the approach that gives better pain relief and comfort after surgery, especially for longer procedures.
DamiettaAges 18–70 - NCT04669457Enrolling by invitationPhase 4
Study of delirium risk in young children having ear surgery
This trial looks at confusion or “delirium” after anesthesia in babies and young children having a myringotomy (ear procedure). It may help doctors understand which children are more likely to experience delirium and how to reduce that risk.
Worcester, MassachusettsAges 3 months–9 years - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT05383495RecruitingPhase 3
Calming medicine during child laceration repair
This trial tests a calming/anxiety-reducing medicine to see if it helps children feel less scared during stitches for a skin cut. It may help make the repair process easier for children and their caregivers.
London, OntarioAges 2–12 - NCT07584434RecruitingPhase 1
Safety and Dosage Study of VX-433 in Healthy People
This is a first-in-human study testing a new drug called VX-433 to see how safe it is and how the body handles it. Vertex Pharmaceuticals is running this early-stage trial to understand the right dosage and side effects in healthy volunteers.
Salt Lake City, UtahAges 18–55 - NCT07476482Enrolling by invitation
Shared decision-making during planned C-section under spinal anesthesia
This trial tests whether involving you in decisions during your planned C-section can improve your experience. You will be awake under spinal anesthesia and the study focuses on helping you feel more in control.
AlexandriaAges 18 years+ - NCT07519863RecruitingPhase 2
Comparing sedation medicines for burned children during procedures
This study tests two different sedation medicine combinations to see which one reduces confusion and agitation (called delirium) when children with burn injuries need procedures done. The goal is to find the safest, most comfortable option for your child during treatment.
CairoAges 3–16 - NCT07600073Recruiting
Comparing two sedation medications for endoscopy procedures
This trial tests whether remimazolam, a newer sedative, works as well as midazolam (a common sedative) for keeping patients comfortable during endoscopy procedures that examine the stomach and pancreas. The study aims to see which medication has fewer side effects.
Lecco, LeccoAges 18 years+ - NCT07289776RecruitingPhase 1
Testing a new medicine in healthy volunteers
This first-in-human trial tests a new medicine called GRT7041 in healthy people to see how safe it is and how it works in the body. It helps doctors understand the right dose and any side effects before testing in patients.
ChristchurchAges 18–60 - NCT07665723RecruitingPhase 1
Study of afimkibart and other medicines in ulcerative colitis
This study looks at how afimkibart affects the way your body processes certain other medicines. It is for people with moderate to severe ulcerative colitis and helps researchers understand how to use this treatment safely.
Chula Vista, CaliforniaAges 18–60 - NCT07746505Recruiting
Remimazolam vs midazolam for anesthesia in older adults
This study compares two sedative medicines used to start general anesthesia in patients 65 and older having non-cardiac surgery. The goal is to see which one is safer and works better for older patients.
HangzhouAges 65 years+ - NCT07227454RecruitingPhase 3
Esketamine for teens with severe depression and suicidal thoughts
This trial tests if esketamine (a nasal spray) can quickly reduce symptoms of major depression and suicidal thoughts in teenagers who need urgent hospital care.
Birmingham, AlabamaAges 12–17 - NCT07569198RecruitingPhase 2
Ketamine plus therapy for depression with suicidal thoughts
This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.
Toronto, OntarioAges 18–70 - NCT07656792RecruitingPhase 1
Testing a new drug in healthy Japanese volunteers
This study tests how well a new drug (BI 3031185) is tolerated by healthy Japanese men. It also checks if the drug changes how a common birth control pill works in healthy Japanese women who cannot become pregnant. The goal is to find a safe dose and understand any interactions.
Fukuoka, FukuokaAges 18–64 - NCT07670377RecruitingPhase 1
Drug interaction study of GSK3772701 in healthy adults aged 18-55
This trial tests how a new drug (GSK3772701) interacts with another common drug (midazolam) in healthy volunteers. It aims to see if one affects how the other works in the body and will help determine safe dosing for future studies.
Miami, FloridaAges 18–55 - NCT05681572RecruitingPhase 3
Sedation before surgery to help kids feel better after anesthesia
This study tests whether giving a calming medicine before general anesthesia improves how children feel and experience anesthesia afterward. The goal is to see which pre-surgery approach works best and is comfortable for kids.
Montpellier, MontpellierAges 7–18 - NCT03016819RecruitingPhase 3
Test drugs anlotinib and catequentinib for advanced sarcoma
This Phase 3 study tests two anti-cancer medicines (anlotinib and catequentinib) for people with certain advanced soft-tissue sarcomas, including alveolar soft part sarcoma, synovial sarcoma, and leiomyosarcoma. It is designed for tumors that cannot be removed and that have either grown despite treatment or no longer respond to standard options.
Phoenix, ArizonaAges 18 years+ - NCT03343873Recruiting
Comparing anesthetics and brain connectivity on MRI
This study tests how different anesthesia medicines affect how brain areas communicate with each other, measured during an MRI scan. It may help researchers understand how anesthesia can change brain networks in both healthy people and people with brain tumors.
BeijingAges 18–65 - NCT04119180RecruitingPhase 4
Sedation vs protective positioning for kids' dental work
This study compares two ways of keeping children comfortable and safe during dental treatment: sedation or a protective positioning approach. It may help find which method works better for comfort and safety for children who need fillings or other cavity repair.
Goiânia, GoiásAges 1–7 - NCT04801589RecruitingPhase 3
Guided sedation for children on a breathing machine
This study tests a “goal-directed” approach to sedation (giving the right amount based on target goals) for children who need a breathing machine in the pediatric ICU. The goal is to reduce brain and recovery side effects while keeping children comfortable and safe.
Nashville, TennesseeAges 10 months–11 years
Common questions
- Are there clinical trials studying Midazolam?
- Yes. Clin2 currently lists 72 recruiting studies that include Midazolam, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Midazolam trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Midazolam an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Midazolam or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.