Treatment
Platelet rich fibrin clinical trials
We’re tracking 51 recruiting studies that include Platelet rich fibrin, each written for real people, not researchers, below.
Recruiting studies
- NCT07316582Enrolling by invitationPhase 4
Melatonin gel for gum disease treatment
This trial tests a new gel made with melatonin and platelet-rich fibrin to treat gum disease. It may help reduce pocket depth and improve gum health without surgery.
New CairoAges 20–60 - NCT07090694Enrolling by invitationPhase 1
Sinus lift with or without platelet-rich fibrin for dental implants
This trial compares two ways to place dental implants in the upper jaw where there is not enough bone: one uses a special clotting substance (PRF) and the other does not. The goal is to see which method works better.
RiyadhAges 25–65 - NCT07088809Enrolling by invitation
Nanoparticles with Platelet-Rich Fibrin for Gum Recession
This trial tests a new material to treat gum recession—tiny particles mixed with your own blood components (platelet-rich fibrin) placed as a membrane. The goal is to see if it helps cover exposed roots and improve gum health.
Tanta, Gharbia GovernorateAges 20–45 - NCT07045545Enrolling by invitation
Comparing two layers in hypospadias repair for young boys
This trial tests two ways to add an extra layer during hypospadias repair surgery in young boys. One method uses a material made from your child's own blood (platelet-rich fibrin), and the other uses a small flap of tissue from the penis. The goal is to see which method helps the healing better.
Tashkent, CityAges Any age - NCT07532161Recruiting
Fibrin and Laser Treatment for Gummy Smile Surgery
This study compares two treatment approaches—liquid fibrin (a clotting substance) and soft laser therapy—to help healing and prevent relapse after surgery to reduce a gummy smile caused by an overactive upper lip. The goal is to find which method works better for long-term results.
Damascus, Rif-dimashq GovernorateAges 18–50 - NCT07752849Recruiting
Platelet-rich fibrin gel for cleft palate repair
This study compares two types of gel made from the patient's own blood, with or without an antibiotic, applied during cleft palate surgery to see if they improve healing and reduce complications.
SanaaAges 3 months–18 years - NCT06516263Recruiting
Effect of L-PRF on dental implant stability and bone levels
This trial tests if a special blood concentrate (L-PRF) placed around dental implants can help them heal better and keep bone levels stable. It may be an option if you need one or more dental implants and have enough natural bone without needing a graft.
DublinAges 18 years+ - NCT06453330Recruiting
Does H-PRF improve dental implant healing?
This trial tests whether a special blood concentrate called H-PRF helps dental implants heal faster and stay more stable in the jawbone. If you need an implant and meet the health and bone requirements, you may be able to join.
DublinAges 18 years+ - NCT06768424Recruiting
Treating deep gum pockets with laser or scalpel and platelet gel
This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.
Budapest, BudapestAges 18–65 - NCT06347263Recruiting
Gum surgery technique for deep pockets between teeth
This trial tests a surgical technique to treat deep gum pockets between teeth. It compares using a special gum-saving method alone, with a bone graft, or with a platelet-rich fibrin injection to see which helps heal the bone best.
CairoAges 18–50 - NCT06657651Enrolling by invitation
Immediate Implant with Different Membranes for Lower Back Teeth
This study tests placing a dental implant and a special membrane right after removing a damaged lower back tooth. It looks at how well different types of membranes help the bone heal around the implant.
Al MansurahAges 18–60 - NCT07150858Recruiting
New bone graft material for sinus lift with implant
This trial tests a new combination of materials (erythropoietin, albumin, and platelet-rich fibrin) to help rebuild bone in the upper jaw during a sinus lift procedure. If you need a dental implant but have limited bone height, this approach may allow the implant to be placed at the same time as the lift.
AlexandriaAges 20–60 - NCT07562334Recruiting
Cheekbone Implants With Two Tissue Coverage Methods
This trial compares two ways to cover and support cheekbone implants (zygomatic implants) in patients with severe upper jaw bone loss. The study tests whether a natural fat pad from your cheek or a special fibrin product (made from your own blood) works better to protect the implant and keep soft tissue thickness stable.
Cairo, Cairo GovernorateAges Any age - NCT07742826Recruiting
Platelet-rich fibrin vs. steroids after wisdom tooth removal
This study compares two treatments to reduce pain and swelling after removing an impacted wisdom tooth: one uses a special blood clot (platelet-rich fibrin) placed in the socket, and the other uses steroid medication. The goal is to find which works better for healing and comfort.
NicosiaAges 18 years+ - NCT07707063RecruitingPhase 4
Gum disease treatment with I-PRF, iodine, or laser in smokers and non-smokers
This trial tests whether adding I-PRF (a concentrate from your own blood), povidone-iodine, or laser treatment to standard deep-cleaning helps smokers and non-smokers with gum disease. You may qualify if you have moderate to severe gum disease with at least one bleeding pocket in each area of your mouth.
Tunis, Mont FleuryAges 18 years+ - NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT06694168Recruiting
Gum surgery to repair bone loss, with or without your own healing proteins
This trial tests a gum surgery technique that preserves more of your gum tissue, with or without a special protein-rich material made from your own blood (L-PRF), to repair bone loss from gum disease.
Santiago, San BernardoAges 18 years+ - NCT06782035Recruiting
Effect of dressings on donor site comfort after gum graft surgery
This trial tests whether special dressings applied to the area where a gum graft is taken from can improve patient comfort and quality of life after surgery.
IzmirAges 18–85 - NCT07081230Recruiting
Albumin vs hyaluronic acid with growth factors for gum disease
This trial tests whether adding albumin or hyaluronic acid (both natural substances) to a special gum treatment helps heal gum pockets better. It is for people with moderate to advanced gum disease.
Al Mansurah, MansouraAges 25–45 - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65 - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT07293962RecruitingPhase 2
Liquid S-PRF for gum disease treatment
This study tests whether a special liquid made from your own blood (called liquid S-PRF) can improve gum health during deep cleaning for people with advanced gum disease. It lasts 3 months and may help reduce inflammation and promote healing without surgery.
Jenjarum, SelangorAges 18–65 - NCT07393997Recruiting
Tooth transplant with platelet-rich fibrin for young patients
This trial tests a tooth transplant method that uses a healthy tooth from elsewhere in your mouth to replace a missing tooth. A special protein-rich material (platelet-rich fibrin) is placed around the new tooth to help it heal and grow roots. It's designed for children, teens, and young adults who cannot get dental implants.
BariAges 10–80 - NCT07424716Recruiting
Bone healing with platelet-rich fibrin after cyst removal
This trial tests whether a natural blood concentrate (PRF) helps jawbone heal better after removing a dental cyst. It may improve recovery and reduce the need for additional bone grafting.
Sanaa, Sanaa GovernorateAges 18–80
Common questions
- Are there clinical trials studying Platelet rich fibrin?
- Yes. Clin2 currently lists 51 recruiting studies that include Platelet rich fibrin, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Platelet rich fibrin trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Platelet rich fibrin an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Platelet rich fibrin or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.