Treatment
Ppi clinical trials
We’re tracking 31 recruiting studies that include Ppi, each written for real people, not researchers, below.
Recruiting studies
- NCT07691138RecruitingPhase 4
Stopping acid-reducing pills in stable IBD
This study tests whether it is safe to stop taking acid-reducing pills (PPIs) for people with inactive IBD. If you have been on a PPI for over 6 months and your IBD is stable, you may be able to join.
NottinghamAges 16 years+ - NCT04868578Recruiting
Vitamin PPI supplements for ectopic calcification in PXE
This trial studies whether taking PPI-type supplements can slow or reduce unwanted calcification in people with PXE. It’s meant to help manage disease changes caused by abnormal calcium deposits, based on your medical testing.
AngersAges 18–65 - NCT06300788Recruiting
Pyrophosphate study in children with kidney disease
This study looks at a natural chemical in the body called pyrophosphate (PPi) in children with chronic kidney disease. It aims to understand how kidney problems affect this chemical, which is important for bone health. The study needs kids with different kidney stages, including those on dialysis, with a transplant, or even healthy kids having surgery for comparison.
Nice, Alpes-MaritimesAges birth–18 years - NCT03647072RecruitingPhase 3
Test drug to reduce stomach side effects during lymphoma chemotherapy
This Phase 3 trial studies whether a proton pump inhibitor (a stomach acid blocker) works better than histamine-blocking medicines when added to chemotherapy for DLBCL lymphoma. The goal is to improve how well chemotherapy is tolerated or how the treatment works.
CairoAges 18 years+ - NCT05773443Recruiting
Digital program plus an oral drug for Lewy body dementia
This study tests an eHealth program together with a patient-and-caregiver support program, along with a medicine called ambroxol. It aims to see whether this combined approach is safe and helpful for people with dementia with Lewy bodies (or early memory changes from it).
Haugesund, RogalandAges 50–85 - NCT07791849Recruiting
Comparing two stomach protectors after stem cell transplant
This study compares two medications, GMPA and PPI, that protect the stomach during a stem cell transplant. It aims to see which one is better at preventing stomach problems and reducing the risk of a complication called graft-versus-host disease (aGVHD), where donor cells attack the patient's body.
HangzhouAges 12–70 - NCT07750379Recruiting
Acid-reducing medicine for aspiration in children with laryngomalacia
This study tests whether giving a common acid-reducing medicine (a proton pump inhibitor) to children with laryngomalacia can reduce choking and aspiration. It may help if your child has frequent choking episodes.
Minya, Minya GovernorateAges 6 months–5 years - NCT05484128Recruiting
Probiotic for kids taking acid-reducing medicine
This trial studies whether a specific probiotic (Lactobacillus reuteri) is helpful for children who need acid-reducing medicine for reflux or stomach discomfort. It may help improve stomach symptoms while they are on or need treatment with proton pump inhibitors.
BariAges 1–14 - NCT07467213RecruitingPhase 3
Acid reflux drug for heart attack recovery
This trial tests if a newer acid-reducing drug is better than standard care for preventing stomach problems in people who recently had a heart attack and a stent placed. It could help those who need stomach protection while on blood thinners.
SeoulAges 19 years+ - NCT07437768Enrolling by invitation
Vonoprazan test for acid reflux that doesn't respond to standard medicine
This trial tests a medicine called vonoprazan for people whose acid reflux symptoms (like heartburn or coughing) don't get better with usual treatment. It aims to see if vonoprazan can help control those symptoms.
New Taipei City, TaiwanAges 20–75 - NCT06248762Recruiting
App for parents: PPI and mindfulness for kids with NDD
This trial tests a digital app that combines PPI (positive psychology exercises) and mindfulness for parents of children with or suspected of a neurodevelopmental disorder (NDD). It aims to help you manage stress and feel better through daily use for about 15 minutes.
EnschedeAges 18 years+ - NCT07293910RecruitingPhase 2
Comparing stomach acid drugs for clearing H. pylori infection
This trial tests different combinations of stomach acid-reducing drugs, vitamin D or probiotics, to see which works best for clearing an H. pylori infection. H. pylori is a common stomach bacteria that can cause ulcers or stomach discomfort.
Shibīn al KawmAges 18–80 - NCT07291700Recruiting
Talcid for acid rebound after stopping long-term PPI therapy
This study tests whether Talcid chewable tablets can relieve the acid reflux symptoms that often happen when you stop taking a long-term daily acid-reducing medicine (like omeprazole). It is for people whose doctor says they no longer need that medicine.
LeverkusenAges 18 years+ - NCT07260006Recruiting
Bismuth therapy for H. pylori ulcers in children
This trial tests whether adding bismuth to standard treatment works better for children with stomach ulcers caused by H. pylori infection. If your child has been diagnosed with an H. pylori ulcer, this study could help find the best medicine.
Can ThoAges 5–15 - NCT07230743Recruiting
Using an interactive projector to reduce anxiety in children during anesthesia
This trial tests whether an interactive projector can help distract children aged 2 to 6 while they are going under anesthesia for surgery, with the goal of lowering their anxiety. It compares the projector to standard care to see if it makes the experience less stressful for the child and family.
Vitacura, Santiago MetropolitanAges 2–6 - NCT07120672Recruiting
Breathing tube removal success study
This study tests if a new method (PPI) can better predict when a patient is ready to have their breathing tube removed after a trial of spontaneous breathing.
IstanbulAges 18 years+ - NCT07063576RecruitingPhase 2/Phase 3
Baclofen for persistent heartburn or regurgitation
This trial tests whether the drug baclofen can help patients who still have acid reflux symptoms (heartburn or regurgitation) despite taking standard treatments like PPIs for 8 weeks. If you've tried PPIs and still have symptoms, this may be an option.
DhakaAges 18 years+ - NCT07045688Recruiting
Vonoprazan for Helicobacter pylori infection
This trial tests vonoprazan-based treatments to see if they can effectively clear H. pylori infection. It may help if you have not been treated for H. pylori before.
SohagAges 19 years+ - NCT07039955Enrolling by invitation
Preventing CPE germ spread in ICU patients
This trial tests whether daily cleansing with a special soap (chlorhexidine) combined with thoughtful use of antibiotics and stomach acid reducers can help prevent the spread of a tough germ called CPE (carbapenemase-producing Enterobacteriaceae) in the ICU. It aims to keep ICU patients safer from infection.
Chuncheon, Gangwon-doAges 19 years+ - NCT07005986Recruiting
Pyrophosphate as a biomarker for artery hardening in type 2 diabetes
This study looks at a substance in the blood called pyrophosphate that may help doctors detect a type of artery hardening (mediacalcinosis) in people with type 2 diabetes. It tests whether this substance can be a useful early warning sign.
Nice, FranceAges 40–70 - NCT06998966Recruiting
Improving PPI prescribing with electronic help
This study tests if a tool in the electronic health record can help doctors prescribe proton pump inhibitors (medicines for heartburn) more effectively. It may lead to better treatment decisions for patients like you.
Los Angeles, CaliforniaAges 50 years+ - NCT06999577RecruitingPhase 4
The Mechanism Versus PPI Trial for throat reflux
This study tests how well omeprazole (a common acid-blocking medicine) works for people with laryngopharyngeal reflux (LPR), a condition where stomach acid irritates the throat. If you have had throat symptoms for more than 8 weeks and are already scheduled for an endoscopy with acid monitoring, you may qualify to see if this medicine helps more than a placebo.
San Deigo, CaliforniaAges 18–89 - NCT06682533Recruiting
Comparing tegoprazan and PPI for H. pylori treatment
This trial compares two different types of stomach-acid-lowering medicines — tegoprazan and a proton pump inhibitor (PPI) — to see which works better at clearing H. pylori infection. It's for people who have not been treated for H. pylori before and can safely have a stomach scope.
SeoulAges 20–80 - NCT06543316Recruiting
Treating gastric bypass ulcers with low-thermal argon plasma
This study tests a new way to treat painful sores (marginal ulcers) that can happen after gastric bypass surgery. Doctors use a special tool (argon plasma) during an endoscopy to help the sores heal faster, and you will get standard ulcer medicine too.
Boston, MassachusettsAges 18 years+
What Ppi is being studied for
Conditions with recruiting Ppi studies.
Common questions
- Are there clinical trials studying Ppi?
- Yes. Clin2 currently lists 31 recruiting studies that include Ppi, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Ppi trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Ppi an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Ppi or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.