Treatment
S-1 clinical trials
We’re tracking 802 recruiting studies that include S-1, each written for real people, not researchers, below.
Recruiting studies
- NCT05879926RecruitingPhase 3
Testing chemo after hormone therapy in premenopausal early breast cancer
This Phase 3 trial checks whether adding chemotherapy after standard hormone-blocking treatment works better for some premenopausal women with early-stage, ER-positive, HER2-negative breast cancer. It targets patients with limited lymph node spread and a lower-to-intermediate tumor “recurrence” risk score.
Birmingham, AlabamaAges 18–60 - NCT07428746RecruitingPhase 3
GLP-1 drug for bone health in older women with diabetes
This study tests whether a diabetes medication called a GLP-1 receptor agonist can help improve bone and muscle health in older women with type 2 diabetes who are at risk for osteoporosis. It aims to see if the drug can strengthen bones and prevent falls.
Atlanta, GeorgiaAges 65 years+ - NCT07740291Recruiting
Tirzepatide and lifestyle study for weight loss
This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.
Lubbock, TexasAges 18 years+ - NCT06547619RecruitingEarly Phase 1
Blood vessel health after pregnancy with diabetes
This study looks at how blood vessels work in women who had a healthy pregnancy or gestational diabetes. It tests if a substance called ET-1 affects blood vessel function.
Iowa City, IowaAges 18–50 - NCT07518979RecruitingPhase 2
EGFR-targeted drug plus immunotherapy for advanced penile cancer
This trial tests a new combination treatment for advanced penile cancer that hasn't been treated before. It combines a targeted drug (becotatug vedotin) designed to attack cancer cells with an immunotherapy drug (pucotenlimab) that helps your immune system fight cancer.
Chengdu, SichuanAges 18 years+ - NCT06413433RecruitingPhase 3
Solriamfetol for binge eating disorder
This study tests whether a drug called solriamfetol can help reduce binge eating episodes. It works on brain chemicals involved in mood and appetite control.
Encino, CaliforniaAges 18–55 - NCT06417892Recruiting
Fruquintinib combo with or without immunotherapy for stomach cancer
This trial tests a combination of two drugs (fruquintinib and albumin-paclitaxel) with or without an immunotherapy drug (PD-1 antibody) as a second-line treatment for advanced stomach cancer. It aims to see if adding immunotherapy improves outcomes for people who have already received immunotherapy before.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07726446RecruitingPhase 2
Freezing, immunotherapy, and chemo for bile duct tumors
This study tests a new treatment approach for bile duct or gallbladder cancer that has not been treated before. It combines a freezing procedure (cryoablation) with an immunotherapy drug (Relaforp Alpha) and chemotherapy to see if it can shrink tumors or slow disease progression.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06512454Recruiting
Study on inherited alpha-1 antitrypsin deficiency and related liver problems
This study looks at how alpha-1 antitrypsin deficiency affects the liver in adults. It aims to learn more about the liver problems caused by this condition and may help find better ways to manage them.
Gainesville, FloridaAges 18 years+ - NCT06568367RecruitingPhase 3
Solriamfetol for shift work disorder (SUSTAIN trial)
This study tests a medication called Solriamfetol (Sunosi) to see if it helps people with shift work disorder stay awake and alert during their shifts. It is a Phase 3 trial, which means it is being studied in a larger group to confirm how well it works and check for side effects.
Auburn, AlabamaAges 18–65 - NCT06134492RecruitingPhase 3
Acyclovir for pneumonia patients with HSV-1 on breathing support
This trial tests whether acyclovir, an antiviral drug, can help patients with pneumonia who are on breathing support and have herpes simplex virus in their lung fluid. The goal is to see if it improves recovery.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT07202546RecruitingPhase 2
New oral HIV drug trial for people new to treatment
This trial tests a new oral HIV medication (VH4524184) in people who have never taken HIV treatment before. It looks at how well the drug controls the virus and how safe it is.
Bakersfield, CaliforniaAges 18 years+ - NCT07723248RecruitingPhase 3
Oral Rinzimetostat for Advanced Prostate Cancer After Abiraterone
This study tests an experimental pill called rinzimetostat (ORIC-944) for men with advanced prostate cancer that has spread and stopped responding to abiraterone. It may offer a new option if you have not had many other treatments yet.
Charlotte, North CarolinaAges 18 years+ - NCT07699939RecruitingPhase 2
Perioperative immunotherapy plus chemo for advanced gastric cancer
This trial tests whether adding the immunotherapy drug HLX10 (serplulimab) to standard chemotherapy (S-1 plus oxaliplatin) before and after surgery can improve outcomes for patients with advanced gastric or gastroesophageal junction cancer that has a high level of PD-L1 protein.
Chiba, ChibaAges 18–80 - NCT06351592RecruitingPhase 1/Phase 2
Study of ALN-SOD for ALS with SOD1 gene mutation
This trial tests an experimental drug called ALN-SOD for people with ALS caused by a specific genetic mutation in the SOD1 gene. The goal is to see if it is safe and can help slow the disease.
Concord, New South WalesAges 18 years+ - NCT07225816RecruitingPhase 1
How fasting affects stomach food with GLP-1 drugs
This study looks at how long fasting and temporarily stopping certain diabetes or weight-loss medications (like semaglutide or liraglutide) affects how much food stays in your stomach. It may help understand how these medications work in people who are overweight.
Cypress, CaliforniaAges 18 years+ - NCT07711223RecruitingPhase 1/Phase 2
New HIV pill compared to standard treatment for untreated adults
This trial compares a new HIV medication (ACC017) to an existing one (dolutegravir) in adults who have HIV but have never taken HIV drugs before. The goal is to see if the new pill works as well and is safe.
BeijingAges 18 years+ - NCT07272837Recruiting
How semaglutide affects heart and muscle mass
This study looks at how semaglutide (Ozempic or Wegovy) changes heart muscle and body muscle. It may help people with type 2 diabetes or those taking the drug for weight loss understand if their heart is affected.
Edmonton, AlbertaAges 18–80 - NCT04301076RecruitingPhase 1
Testing lenalidomide with EPOCH for adult T-cell leukemia-lymphoma
This trial tests whether adding lenalidomide to a standard chemotherapy regimen (EPOCH) helps people with adult T-cell leukemia-lymphoma (ATLL). It aims to improve how well the treatment works.
Atlanta, GeorgiaAges 18 years+ - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Los Angeles, CaliforniaAges 6 months–26 years - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT03259867RecruitingPhase 2
TACE plus immune therapy for liver or stomach cancer
This trial tests a combination treatment using a targeted liver procedure plus an immune “checkpoint” medicine to slow cancer growth. It may help people with advanced liver cancer (HCC) or metastatic stomach cancer when standard treatments have not worked.
Orange, CaliforniaAges 18–80 - NCT03326921RecruitingPhase 1
T cell treatment for leukemia after a bone marrow transplant
This early-phase trial tests an immune “T cell” therapy made to recognize a specific leukemia target. It is for people whose acute leukemia has come back (relapsed) or did not fully respond after receiving a donor stem cell transplant.
Seattle, WashingtonAges Up to 80 years
Common questions
- Are there clinical trials studying S-1?
- Yes. Clin2 currently lists 802 recruiting studies that include S-1, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a S-1 trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is S-1 an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether S-1 or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.