Treatment
Tramadol clinical trials
We’re tracking 18 recruiting studies that include Tramadol, each written for real people, not researchers, below.
Recruiting studies
- NCT07810816Recruiting
Genetic testing for personalized pain relief after surgery
This study looks at how your genes affect your body's response to tramadol, a painkiller given through a pump after surgery. The goal is to see if your genetic makeup influences pain relief and side effects, which could help personalize pain treatment in the future.
Medellín, AntioquiaAges 18 years+ - NCT07110051Recruiting
Pain relief after abdominal surgery in children with cancer
This trial compares two pain medicines, nalbuphine and tramadol, to see which works better for children with cancer after abdominal surgery. The goal is to find the safest and most effective way to manage pain.
CairoAges 3–12 - NCT06722742RecruitingPhase 3
Preventing shivering after spinal anesthesia for cesarean
This trial tests whether two common medicines, tramadol and ketamine, given through an IV, can prevent shivering that sometimes happens after spinal anesthesia for cesarean section. You may be able to join if you are having a planned cesarean and are generally healthy.
Karachi, SindhAges 18–40 - NCT07440069RecruitingPhase 4
Pain relief options for women during active labor
This trial compares the pain relief and effects of tramadol, paracetamol (also known as acetaminophen), and a placebo in women during active labor. It aims to find which option works best and is safest for mothers and babies.
Tegucigalpa, Francisco Morazán DepartmentAges 15–45 - NCT07264309Recruiting
Pain relief options for women in early labor
This trial compares two pain relief methods during the first stage of labor: a combination of tramadol and paracetamol given through an IV, versus pethidine given as a shot. The goal is to see which works better and has fewer side effects.
AfulaAges Any age - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal
This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.
Karachi, SindhAges 18–50 - NCT06274333RecruitingPhase 3
Easing bladder discomfort after kidney stone surgery
This trial tests if adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder pain and discomfort from the urinary catheter used during kidney stone removal. It may help patients feel more comfortable after their procedure.
Cairo, Cairo GovernorateAges 20–50 - NCT07840183RecruitingPhase 4
Epidural versus other pain relief for open ventral hernia repair
This study compares two ways to manage pain after hernia repair surgery: using an epidural (a small tube in your back that delivers pain medicine) versus other pain medications that aim to reduce opioid use. The goal is to see which method provides better pain relief and helps you recover more comfortably.
Chicago, IllinoisAges 18–80 - NCT07775053Enrolling by invitation
Pain relief study for breast cancer surgery
This study tests whether adding tramadol to a standard numbing medicine (ropivacaine) makes pain control better after breast cancer surgery. If you're having a mastectomy, this could help reduce pain and improve recovery.
Sargodha, Punjab ProvinceAges 20–70 - NCT07721571Recruiting
Numbing medicine around drainage tube for kidney stone surgery pain
This study tests whether injecting a local numbing medicine around the nephrostomy tube after kidney stone surgery can reduce pain after the procedure. If you are having this surgery, it may help you feel more comfortable during recovery.
Çorum, ÇorumAges 18–75 - NCT06656299Recruiting
Nerve block for gallbladder removal surgery
This study tests a nerve block called EOIB to see if it helps reduce pain after gallbladder removal surgery. If you are having planned gallbladder surgery, this might be a good option for you.
IstanbulAges 18–65 - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07289321Enrolling by invitation
Pain relief study for robotic prostate surgery
This trial tests if adding tramadol and magnesium to a local anesthetic (ropivacaine) improves pain control after robotic prostate removal. It may help reduce the need for strong painkillers after surgery.
Athens, AtticaAges 40–80 - NCT07241949Recruiting
Nerve block for gallbladder surgery pain relief
This study tests a nerve block called the external oblique intercostal block to reduce pain after laparoscopic gallbladder removal. If you are having this surgery, the block may help you need less pain medication and feel more comfortable after the procedure.
AdanaAges 18–65 - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT07060209RecruitingPhase 1
How food affects a new painkiller in healthy adults
This study tests how a meal affects the absorption of a combination painkiller (pelubiprofen and tramadol) in healthy adults. It helps understand if taking the drug with food changes how well it works.
Haiphong, Hai PhongAges 18–45 - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65
What Tramadol is being studied for
Conditions with recruiting Tramadol studies.
Common questions
- Are there clinical trials studying Tramadol?
- Yes. Clin2 currently lists 18 recruiting studies that include Tramadol, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Tramadol trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Tramadol an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Tramadol or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.