Treatment
Treatment as Usual clinical trials
We’re tracking 315 recruiting studies that include Treatment as Usual, each written for real people, not researchers, below.
Recruiting studies
- NCT07194083Recruiting
Study on a treatment for wandering in children with autism
This trial tests a function-based treatment to reduce elopement (wandering away) in children with autism. It may help if your child wanders regularly and you are looking for a behavioral approach.
Atlanta, GeorgiaAges 4–12 - NCT07263321Recruiting
Depression treatment choice in general practice
This study helps people with moderate depression decide between medication and therapy. Your doctor will work with you to pick the best option.
AalborgAges 18–65 - NCT03887559Recruiting
Group therapy for long-lasting trauma reactions in everyday clinics
This study tests a structured group program to help people manage long-lasting trauma-related symptoms such as feeling “on edge,” avoiding reminders, upsetting memories, strong emotions, or relationship problems. It may help you learn skills and stabilize symptoms while you continue care through regular outpatient clinics.
TrondheimAges 18–75 - NCT07073066Recruiting
Lymphatic surgery for Alzheimer's disease (CLEAN-AD trial)
This trial tests a surgical procedure that connects lymphatic vessels in the neck to help clear waste from the brain in people with moderate-to-severe Alzheimer's disease. The goal is to see if this can improve thinking and memory.
Dongguan, GuangdongAges 50–80 - NCT07303608Recruiting
Tracking progress in social services to improve outcomes
This study looks at whether regularly checking in on your progress and giving feedback to your social worker can help improve the support you receive. If you are getting help from social services, you may be able to take part.
LinköpingAges 15 years+ - NCT07015944Recruiting
Moving on after breast cancer: a depression trial for survivors in Pakistan
This study tests a program called "Moving on After Breast Cancer" for women in Pakistan who have finished breast cancer treatment and now have depression. The goal is to see if this program helps them feel better emotionally.
Karachi, SindhAges 18 years+ - NCT07501507RecruitingPhase 2/Phase 3
Methotrexate for hand osteoarthritis not helped by usual treatments
This trial tests if methotrexate, a medicine that reduces inflammation, can ease pain and improve function in people with hand osteoarthritis that hasn't gotten better with standard treatments like pain relievers or hand therapy.
NiceAges 40–85 - NCT07200713Recruiting
SMART therapy for trauma-affected youth
This trial tests a therapy called SMART for youth who have experienced trauma. It aims to help with emotional, behavioral, and relationship problems linked to that trauma.
Asker, AkershusAges 7–17 - NCT06928480Recruiting
Unified Protocol for Emotional Health in Long COVID
This study tests a program to help people with Long COVID manage emotional difficulties like depression or anxiety. It combines different therapy approaches into one treatment, which you can receive online from home.
Zaragoza, ZaragozaAges 18 years+ - NCT06390462Recruiting
Counseling for teens in school-based primary care
This study tests a brief counseling approach called Interpersonal Counseling for Adolescents (IPC-A) in school settings. It aims to help teens with emotional or social challenges before they become more serious, and it's designed for those who aren't already in mental health treatment.
HämeenlinnaAges 13–16 - NCT05973786RecruitingPhase 3
Six-week medicine boost for bipolar depression after first treatment fails
This trial tests whether a stronger, more active medication plan for six weeks helps people with bipolar depression who did not improve with their first prescribed treatment. It compares the intensified medication plan to usual care to see which approach works better.
InnsbruckAges 18 years+ - NCT05973851RecruitingPhase 3
Six-week medicine boost for depression after first treatment failure
This study tests a more intensive antidepressant medicine approach for people whose first tried treatment didn’t work well enough. It compares the intensified treatment with usual care, aiming to improve depression symptoms and daily functioning.
InnsbruckAges 18–65 - NCT05969080Recruiting
Therapy program to support recovery after self-harm
This study looks at a treatment and recovery approach for veterans who have had recent non-suicidal self-injury. It may help by testing ways to reduce self-harm urges and support safer recovery over time.
Durham, North CarolinaAges 18 years+ - NCT05169385Recruiting
Parent support for teens in residential treatment for substance misuse
This trial tests a parent-focused program (via interviews and texting) for families when a teen is leaving residential treatment. It aims to help parents/guardians support their teen after discharge and reduce substance-related risk.
Rockford, IllinoisAges 12–18 - NCT07097142RecruitingPhase 3
Shorter radiation for bladder cancer with chemo
This trial tests if a shorter course of radiation therapy works as well as the usual longer course for people with bladder cancer who are also receiving standard chemotherapy. The goal is to see if shorter treatment can reduce side effects while still being effective.
Fort Smith, ArkansasAges 18 years+ - NCT05846841Recruiting
Personalized quit-smoking support in primary care
This study tests a personalized tobacco (smoking) treatment plan delivered in primary care to help reduce cravings and smoking. It may help you quit or smoke less using options like nicotine patches/lozenges or varenicline, chosen to fit your needs.
St Louis, MissouriAges 18 years+ - NCT06616584RecruitingPhase 2/Phase 3
Cemiplimab plus standard care for advanced lung cancer after prior treatments
This trial tests whether adding the immunotherapy drug cemiplimab to standard treatment can help people with advanced lung cancer that has already progressed after both platinum chemo and a prior immunotherapy. It is designed for those who responded to their first immunotherapy for at least 12 weeks before the cancer started growing again.
Daphne, AlabamaAges 18 years+ - NCT05890352RecruitingPhase 2
Add new medicines to standard treatment for returning lymphoma
This Phase 2 study tests whether adding tafasitamab, lenalidomide, tazemetostat, and zanubrutinib (along with standard lymphoma treatment) can improve outcomes in people whose large B-cell lymphoma has returned or not responded. It may help control disease more effectively and improve response duration for eligible patients.
Tucson, ArizonaAges 18 years+ - NCT07463807RecruitingPhase 1/Phase 2
Comparing two drug combinations for multiple myeloma that returned quickly
This study tests a new combination of two drugs, teclistamab and pomalidomide, against the usual treatment of three drugs for multiple myeloma that has come back shortly after a standard treatment. The goal is to see if the new combination works better or is safer.
Duarte, CaliforniaAges 18 years+ - NCT06577441RecruitingPhase 2
Adding enasidenib to usual care for higher-risk MDS with IDH2 mutation
This trial tests whether adding enasidenib (a targeted pill) to the standard chemotherapy (cedazuridine-decitabine) works better than the chemotherapy alone for people with higher-risk myelodysplastic syndrome (MDS) whose cells have a specific change in the IDH2 gene.
Berkeley, CaliforniaAges 18 years+ - NCT07299695RecruitingPhase 3
IVIG for sudden worsening of IPF
This trial tests whether giving a medication called intravenous immunoglobulin (IVIG) can help people with IPF who are hospitalized for a sudden worsening of their lung condition. The treatment aims to reduce inflammation and improve recovery.
PátraiAges 18 years+ - NCT06917911RecruitingPhase 2
Testing two drug additions to standard chemotherapy for a type of acute myeloid leukemia
This trial tests whether adding venetoclax or gemtuzumab ozogamicin to the usual chemotherapy helps people with a specific genetic type of acute myeloid leukemia (AML) respond better. It may improve chances of remission.
Birmingham, AlabamaAges 18–59 - NCT07578116RecruitingPhase 3
Adding surgery and radiation for her2-positive breast cancer with a few spread spots
This trial tests whether adding surgery and radiation to the usual HER2-targeted treatment helps people with breast cancer that has spread to a few spots. You must have HER2-positive cancer that is newly spread, and you must be able to receive radiation to all tumor sites.
Jonesboro, ArkansasAges 18 years+ - NCT07466420Recruiting
Quercetin for fibrotic lung disease
This trial tests whether taking quercetin, a natural supplement, can help people with fibrotic interstitial lung diseases (a group of conditions that cause scarring in the lungs). If you have been diagnosed with idiopathic pulmonary fibrosis (IPF) or another fibrotic ILD and are on standard treatments, you may be able to join.
Heraklion, CreteAges 18 years+
Common questions
- Are there clinical trials studying Treatment as Usual?
- Yes. Clin2 currently lists 315 recruiting studies that include Treatment as Usual, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Treatment as Usual trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Treatment as Usual an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Treatment as Usual or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.