Clin2
NCT04080440Possibly a fitRecruiting

Checking readiness to remove the breathing tube after brain injury

Mechanical Ventilator WeaningAcute Brain InjuryAltered Level of ConsciousnessMechanical VentilationAirway Control

Part of Brain & nervous system, Heart & circulation, Injuries & trauma, Mental health clinical trials.

This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
660 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 to 75 years old and were admitted to the ICU for a brain-related problem causing intubation
  • You have been on a mechanical ventilator for more than 48 hours
  • Your brain status is stable for safety (no dangerous pressure in the head) and you are on minimal sedation
  • You scored low on a basic brain-awareness scale and you passed a spontaneous breathing trial
  • This would be your first attempt to have the breathing tube removed under the study plan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05069441Recruiting
Predicting breathing trouble after removing a breathing tube

This study looks at patients who are ready to have their breathing tube removed and checks how to predict who might struggle after extubation. It’s observational, meaning your care won’t be changed—researchers are gathering information to improve future predictions.

Chongqing
NCT07120438Not yet recruiting
Using ultrasound to predict breathing tube removal in ICU patients

This study compares two ways to check if a patient on a breathing machine is ready to have the tube removed. It uses an ultrasound to look at the diaphragm muscle, which helps doctors decide when it's safe to take the tube out.

NCT06593288Not yet recruiting
Testing when to take a child off a breathing machine

This trial tests a procedure called a spontaneous breathing trial to see how well your child can breathe on their own after being on a ventilator. If successful, it may help doctors decide when to safely remove the breathing tube.

Ribeirão Preto, São Paulo
NCT07067671Not yet recruiting
Breathing support weaning in brain injury patients

This study looks at how well patients with brain injuries breathe on their own when doctors remove the breathing machine. It may help doctors find better ways to support recovery.

Paris, France
NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators

This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.

Iowa City, Iowa
NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients

This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.

Tanta, Mahala

Hear when a new Mechanical Ventilator Weaning trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.