Clinical trials
Mechanical Ventilator Weaning clinical trials
Below are recruiting mechanical ventilator weaning clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT07750288Recruiting
Understanding breathing difficulty in children with lung injury
This study looks at how severe breathing difficulty (dyspnea) affects the recovery of children with a lung condition called acute respiratory distress syndrome (ARDS). It aims to improve care by tracking symptoms over time.
SantiagoAges 1 month–18 years - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT06465082Recruiting
Can diaphragm ultrasound predict successful breathing tube removal?
This trial uses ultrasound to measure how well your diaphragm (the main muscle you use to breathe) thickens when you breathe in. The goal is to see if this measurement can help doctors decide the best time to remove the breathing tube safely.
Al MansurahAges 18 years+ - NCT06391424Recruiting
Oxygen use and breathing effort during ventilator weaning
If you are on a breathing machine in the ICU and ready to try breathing on your own, this study looks at how much oxygen your body uses during that test. It may help doctors better understand when you are ready to come off the ventilator.
Leiden, South HollandAges 18 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT07630662Recruiting
Breathing Muscle Function and Ventilator Weaning Success
This study looks at whether testing the strength and function of your breathing muscles (diaphragm and chest wall muscles) can predict whether you're ready to come off a ventilator (breathing machine). The goal is to help doctors make better decisions about when patients are ready to breathe on their own.
CairoAges 18 years+ - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT07455214Recruiting
Heart rate variability and breathing trial success in ventilated patients
This study looks at whether heart rate patterns can help predict if a person on a breathing machine is ready to breathe on their own. It may help doctors decide the best time to try removing the breathing tube.
New Taipei CityAges 18–85 - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT07467265Recruiting
Testing a breathing test to safely remove ventilators
This study is testing a simple way to measure how well you breathe on your own when coming off a ventilator in the ICU. It helps doctors decide the best time to safely remove the breathing tube.
Cairo, AbbasiaAges 22 years+ - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT06754670Recruiting
How low phosphate affects breathing after ventilator use
This study looks at how low phosphate levels in the blood affect your ability to breathe on your own when coming off a ventilator. If you are already getting better and ready to start breathing without the machine, the results may help doctors understand and manage your recovery better.
BeijingAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65
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Common questions
- Are there clinical trials for mechanical ventilator weaning?
- Yes. Clin2 currently lists 67 recruiting mechanical ventilator weaning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilator weaning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilator weaning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.