Hydrocortisone trial for adrenal symptoms after stopping steroid pills
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Hormones & metabolism, Immune system & allergy, Skin clinical trials.
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 50 or older
- You have had PMR or GCA, and you stopped prednisolone at least 2 weeks ago but less than 12 weeks ago
- You were on prednisolone for at least 12 weeks before stopping
- You do not already have adrenal insufficiency (from problems with the adrenal glands or the brain)
- You do not have Cushing’s syndrome (a condition caused by too much steroid effect)
- You are able to give written informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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