New procedure vs standard pill for adrenal-related high blood pressure
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study tests if a new procedure (blocking tiny adrenal arteries) works as well as a standard pill (spironolactone) for lowering high blood pressure caused by too much aldosterone from both adrenal glands. It is designed for people whose high blood pressure is due to idiopathic hyperaldosteronism.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 15 and 60 years old.
- You have been diagnosed with a condition called primary aldosteronism (high blood pressure from too much aldosterone) and the specific type is idiopathic hyperaldosteronism (not a single nodule).
- Your kidney function is good (eGFR at least 45 and creatinine level normal).
- You have not had a stroke, heart attack, or stent placement in the last 3 months.
- You are not pregnant or planning to become pregnant.
- You are not severely allergic to contrast dye (used in imaging tests).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study uses a new, precise blood test to help diagnose primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. It compares results from healthy volunteers and patients with suspected primary aldosteronism to see if it works better than current methods.
This study is developing a better blood test to diagnose primary aldosteronism, a condition where the adrenal glands produce too much of a hormone called aldosterone, causing high blood pressure. Researchers are comparing results from healthy volunteers and patients suspected of having this condition to find the right cutoff numbers for the new test.
This study tests a procedure that blocks tiny arteries in the adrenal gland to treat high blood pressure and low potassium caused by aldosteronism. It may be an option if you cannot take medications or cannot have surgery.
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This study compares two treatments for primary aldosteronism (a condition causing high blood pressure due to an adrenal gland issue). One treatment is a minimally invasive procedure called superselective embolization, and the other is keyhole surgery. This trial aims to see which is better and safer for patients.
This trial studies whether a specific treatment (related to spironolactone/aldosterone support) can improve how well your blood vessels work in people with primary aldosteronism. It may help reduce blood pressure risk by improving blood vessel health.
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