Quenching complement to protect brain cells after stroke
Treatments studied
Part of Blood & lymphatic, Brain & nervous system, Heart & circulation clinical trials.
This study tests a new drug (EMPAVELI) that may help protect the brain after a stroke. It is given after a procedure to restore blood flow, and the goal is to see if it can reduce damage and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 80 years old.
- Have had a large vessel occlusion stroke and a successful thrombectomy (procedure to remove the clot) within the last 24 hours.
- Weigh at least 50 kg (about 110 pounds).
- Have certain blood counts within an acceptable range (reticulocytes, platelets, and neutrophils).
- Be willing to get or have gotten vaccinations against meningitis, pneumonia, and Haemophilus influenzae type B within the timeframe.
- For women who can become pregnant: negative pregnancy test and agree to use birth control during the study and 90 days after; for men: agree to use birth control and not donate sperm during the study and 90 days after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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