Cartilage, joint pain, and imaging in people taking tirzepatide
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Hormones & metabolism, Skin clinical trials.
This study follows people who are already taking tirzepatide (for diabetes, weight, or related conditions) and who also have joint or muscle problems, such as joint pain, psoriatic arthritis, or knee osteoarthritis. It uses special imaging and blood tests to see how tirzepatide affects joints and cartilage over a year.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are currently taking tirzepatide for any health reason and plan to continue it for at least a year.
- You have a history of joint or muscle problems, such as joint pain with signs of inflammation, psoriatic arthritis, knee osteoarthritis, or tendon/muscle attachment pain.
- You are willing to have blood drawn and stored for research, have two knee MRIs and two heart CT scans (without contrast dye) during the study, and allow researchers to look at your medical records.
- You are not pregnant or breastfeeding, and you are not planning to become pregnant during the next year.
- You do not have any metal implants or devices that are unsafe for MRI, and you are not too claustrophobic to have an MRI without sedation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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