Clinical trials
Ablation clinical trials
Below are recruiting ablation clinical trials, each written for real people, not researchers. We’re tracking 658 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05021601Recruiting
Ablation method comparison for rheumatic valve and ongoing AF
This study compares two heart procedures—targeting one or both upper heart chambers versus only the left upper chamber—to treat people with ongoing atrial fibrillation caused by rheumatic mitral valve disease. It aims to see which approach works better and is safer for restoring normal rhythm.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05023772Recruiting
Laser and targeted radiation for spine metastases
This trial tests a combination treatment that uses a laser and focused radiation to shrink tumors in the spine and help stabilize the area near the spinal cord. It’s meant for adults with certain types of solid cancers that have limited spread in the spine and who are not good candidates for surgery.
Detroit, MichiganAges 18 years+ - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT05444478Recruiting
Microwave ablation plus lenvatinib for recurrent liver cancer
This trial tests whether combining heat treatment to kill liver tumors (microwave ablation) with the medicine lenvatinib can better control recurrent hepatocellular carcinoma (HCC). It may help shrink tumors or slow growth for people whose cancer has come back but who have limited tumor burden.
Changsha, HunanAges 18–75 - NCT05717725RecruitingPhase 3
Pulsed heart ablation vs fake procedure for irregular heartbeat
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
PragueAges 18 years+ - NCT05961982Recruiting
EUS-guided heat treatment for pancreatic cysts
This study tests whether an endoscopy-based “radiofrequency ablation” (controlled heating) can manage certain pancreatic cysts that look high-risk. It’s designed for people who are not good candidates for surgery, aiming to shrink or control the cyst safely.
Columbus, OhioAges 18 years+ - NCT05991856Recruiting
Comparing ablation vs. surgery for adrenal tumors causing high blood pressure
This trial compares two treatments—ultrasound-guided ablation and laparoscopic adrenalectomy—for a type of adrenal tumor called aldosterone-producing adenoma (APA) that causes high blood pressure and low potassium. The goal is to see which treatment works better for patients with a single, non-cancerous tumor.
Guangzhou, GuangdongAges 18 years+ - NCT06145906Recruiting
Optimizing catheter ablation for atrial fibrillation
This trial is studying a way to improve the entire process of catheter ablation for atrial fibrillation. It may help people who are having this procedure for the first time and have a normal-sized left atrium and good heart function.
Zhengzhou, HenanAges 18–80 - NCT06165510Recruiting
Convergent ablation and left atrial appendage isolation for persistent AF
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
LondonAges 18–80 - NCT06356779Recruiting
Studying local treatment for a few cancer spots
This study is for people with solid tumors that have spread to a few spots (5 or fewer) in the body. It tests whether using a focused treatment like radiation or ablation on those spots can help control the cancer long-term.
Copenhagen, Capital Region of DenmarkAges 18 years+ - NCT06383975Recruiting
Two new treatments for AF that returned after first procedure
This trial tests two new treatments for persistent atrial fibrillation that came back after an initial procedure. One uses a targeted chemical injection, the other uses a special energy field to re-isolate the veins involved.
BrugesAges 18 years+ - NCT06402617Recruiting
Ablation of active spots in atrial fibrillation
This trial is testing a new way to treat atrial fibrillation by using a catheter to target the specific areas in the heart that trigger the irregular heartbeat. If you have persistent atrial fibrillation and haven't had prior catheter ablation, you may be eligible to join.
LondonAges 18–85 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Atlanta, GeorgiaAges 18–65 - NCT06426992Recruiting
Microwave ablation for small liver tumors
This study tests a microwave ablation device to destroy small liver tumors (up to 4 cm) using heat, without major surgery. It is designed for patients with limited disease (1 or 2 tumors) and good liver function.
SeoulAges 20–85 - NCT06506149Recruiting
Microwave ablation for relapsed Graves' disease
This study tests if microwave ablation (a heat-based treatment) can help people whose Graves' disease returned after medication. It is a non-surgical option that may avoid lifelong medication or surgery.
Hong KongAges 18 years+ - NCT06514703Recruiting
CT vs. X-ray Guided Nerve Ablation for Knee Arthritis
This study compares two different image-guided techniques (CT scan vs. fluoroscopy) to perform a nerve ablation procedure that blocks pain signals from the knee. It aims to find which method works better for reducing pain in people with knee osteoarthritis.
Zagazig, Sharqia ProvinceAges 45–80 - NCT06556485Recruiting
Early ablation for heart failure patients with heart pumps or on transplant list
This trial tests whether doing a catheter ablation early (before dangerous heart rhythms start) can help people with severe heart failure who need a heart transplant or already have an ICD. The goal is to see if this can improve outcomes.
Bad OeynhausenAges 18–99 - NCT06557876Recruiting
Pulse field ablation for atrial fibrillation mechanics
This study tests if a new type of energy called pulse field ablation (a procedure that uses short bursts of electric pulses) works as well as standard ablation for restoring normal heart rhythm in patients with episodes of irregular heartbeat. It may help your heart pump more normally.
Paris, FranceAges 18 years+ - NCT06573853Recruiting
Comparing two types of ablation for fast heart rhythm
This trial compares two ablation methods (pulsed field vs. radiofrequency) to treat a fast heart rhythm called PSVT. It aims to see which works better and has fewer risks.
Ningbo, ZhejiangAges 18–80 - NCT06609850Recruiting
Comparing TACE plus lenvatinib with or without ablation for recurrent liver cancer
This trial compares two treatments for people whose liver cancer has come back (recurrent intermediate-stage hepatocellular carcinoma). One group gets TACE plus lenvatinib (a targeted therapy), the other gets TACE plus lenvatinib plus ablation (a procedure that destroys tumors with heat or cold). The goal is to see which combination works better.
Beijing, None SelectedAges 18–75 - NCT06609876Recruiting
Donafenib after ablation for recurrent liver cancer
This trial tests whether taking the drug donafenib after a procedure called ablation (which destroys liver tumors) can help keep your liver cancer from returning. It is for people whose liver cancer has come back within the past year and who have small, treatable tumors.
Beijing, None SelectedAges 18–75 - NCT06644430Recruiting
Burning lung spots plus systemic therapy for liver cancer
This trial tests whether burning away a few cancer spots in the lungs (called ablation) can help people with liver cancer who are already on a systemic treatment. If you have stable liver cancer and only a few lung spots that haven't grown, you may be eligible.
Beijing, Beijing MunicipalityAges 18–80 - NCT06647251Recruiting
Comparing different radiofrequency modes for atrial fibrillation ablation
This trial tests three different ways of delivering radiofrequency energy using a specific catheter (QDOT) during a first-time procedure to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to find which method works best for patients with recent or short-lasting AF episodes.
Paris, ParisAges 18 years+ - NCT06703489Recruiting
New catheter for ventricular tachycardia
This trial tests a new catheter system (Sphere-9 and Affera) to treat a fast, dangerous heartbeat called ventricular tachycardia (VT) in people with heart scarring. It aims to see if this system is safe and effective at stopping VT, especially if past treatments haven't worked.
Boston, MassachusettsAges 18–85
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Common questions
- Are there clinical trials for ablation?
- Yes. Clin2 currently lists 658 recruiting ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.