Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 401 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05025774Recruiting
Exercise program study for young heart, leukemia, and lung survivors
This study looks at how an exercise program affects fitness and lung function in young people who are survivors of certain conditions (heart transplant, leukemia, or lung disease from prematurity). The goal is to see whether exercise can improve breathing and overall physical function safely.
Minneapolis, MinnesotaAges 8–25 - NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+ - NCT05417685Enrolling by invitation
Digital physical therapy for musculoskeletal pain
This trial studies a smartphone/tablet-based care program to help people with neck, back, shoulder, elbow, wrist/hand, hip, knee, or ankle pain. It may help reduce pain and improve function using guided exercises, as long as it is safe for you to do light-to-moderate activity.
Draper, UtahAges 18 years+ - NCT06101862Recruiting
CT scan vs. angiogram for certain heart attacks
This trial compares two ways to look at heart arteries: a CT scan (noninvasive) versus a traditional angiogram (a tube put into an artery). The goal is to see which is better for people having a certain type of heart attack.
Copenhagen, HellerupAges Any age - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85 - NCT05728216Recruiting
Using a special eye-scan to study kidney biopsy samples
This study tests whether a noninvasive “eye-scan” during a kidney biopsy can help doctors tell the difference between acute kidney injury and chronic kidney disease. If it works, it may improve how kidney problems are diagnosed in routine practice.
Chalon-sur-Saône, Saône-et-LoireAges 18 years+ - NCT07645469RecruitingPhase 1
WT1-targeting T cells with azacitidine for AML
This trial tests a new type of cell therapy for people with acute myeloid leukemia (AML) that has minimal residual disease (small amounts of cancer left after treatment). The therapy uses your own immune cells, modified to target a protein called WT1 on leukemia cells, and combines it with a drug called azacitidine.
Seattle, WashingtonAges 18 years+ - NCT07170085Recruiting
Positioning for babies with breathing problems
This trial tests if different body positions help babies under 1 year old with breathing problems breathe better while on oxygen support (High-Flow or CPAP).
OdenseAges Up to 1 year - NCT07335341Recruiting
Liberant thrombectomy system case survey
This survey collects feedback from doctors who used the Liberant system to remove blood clots. The results help understand how well the device works in real-life procedures.
Washington D.C., District of ColumbiaAges 22 years+ - NCT06652776Enrolling by invitation
Italian COPD patient registry study
This study is creating a registry to better understand Chronic Obstructive Pulmonary Disease (COPD) in Italian patients. It will collect information from people with COPD to improve care and research.
Milan, MilanAges 40 years+ - NCT07674264Recruiting
Breathing therapy for thinking and movement in Parkinson's
This study tests whether a breathing-based therapy (short bursts of controlled air with higher carbon dioxide) can help with thinking and movement in people with Parkinson's disease. It may be an option for those who are not too advanced in their condition and are healthy enough to participate.
Gainesville, FloridaAges 40–75 - NCT07536035Recruiting
Comparing Hospital Care Pathways for Acute Medical Illness
This study compares two different hospital care pathways for adults admitted with acute medical emergencies like infections, falls, or COPD flare-ups. The goal is to see which pathway provides more appropriate and effective care.
SingaporeAges 21 years+ - NCT05443425RecruitingPhase 1
Leflunomide plus steroids for acute graft-versus-host disease
This early-phase trial tests whether adding leflunomide to standard steroid treatment can better control acute graft-versus-host disease (aGvHD) after a stem cell transplant. It may help reduce the immune reaction that damages the body while keeping treatment safe and manageable.
Duarte, CaliforniaAges 18 years+ - NCT04049539RecruitingPhase 1/Phase 2
Vyxeos for AML that stays after initial chemotherapy
This trial tests whether Vyxeos (a type of chemotherapy) can treat acute myeloid leukemia (AML) that did not fully go away after standard induction (“7+3”) chemotherapy. It targets people whose leukemia is still present in the bone marrow and need a stronger “re-induction” treatment.
Sacramento, CaliforniaAges 18–75 - NCT06690684Enrolling by invitation
Finding new blood markers for heart disease
This study is looking for people who have had a heart attack or have heart failure to discover new markers in your blood that could help doctors better understand and treat heart disease. By collecting samples and health data, researchers hope to find clues that improve care for future patients.
Shanghai, Jing 'an DistrictAges 30 years+ - NCT07613099RecruitingPhase 3
Testing a new PET scan to detect lung and heart scarring
This study tests a new imaging scan (called 18F-FAPI PET/CT) that may help detect scarring in the lungs, heart, or blood vessels. If you have a heart, lung, or blood vessel condition that could cause scarring, this scan might show damage earlier and help doctors plan better treatment.
Bethesda, MarylandAges 18–100 - NCT07159269Recruiting
Cardiac ultrasound training for emergency department providers
This study teaches nurse practitioners and physician assistants in the emergency department how to use a special type of heart ultrasound (called cardiac point-of-care ultrasound). The goal is to help these providers quickly and accurately check the heart at the bedside.
Durham, North CarolinaAges 18 years+ - NCT07231939Recruiting
Testing diabetes drugs to protect kidneys after heart procedures
This study is testing whether a class of diabetes medicines called SGLT2 inhibitors (specifically empagliflozin or dapagliflozin) can prevent kidney injury after heart procedures that use contrast dye.
BydgoszczAges 18 years+ - NCT07231835Recruiting
Coronary outcomes with drug-coated balloon treatment
This study tracks patients who receive a special balloon coated with medicine (paclitaxel) to open blocked heart arteries. It aims to understand how well this treatment works for various types of blockages.
AmsterdamAges 18 years+ - NCT07340723RecruitingPhase 2
New treatment study for grade II acute GVHD after transplant
This study tests a new first-line therapy for patients who develop grade II acute graft-versus-host disease (GVHD) after their first stem cell transplant. It aims to find better ways to treat this complication.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07509749RecruitingPhase 2
New treatments for severe acute GVHD after stem cell transplant
This trial tests new medications for people who develop severe acute graft-versus-host disease (aGVHD) within 100 days after their first stem cell transplant. The goal is to find safer, more effective ways to control aGVHD and improve recovery.
BeijingAges 14 years+ - NCT06026436Recruiting
Predicting clot and bleeding risk in kidney disease patients after a heart attack
This trial tests whether a blood test looking at platelets and tiny cell particles can help predict future blood clots or bleeding in people who have both chronic kidney disease and a recent heart attack. The goal is to improve treatment safety.
MarseilleAges 18–90 - NCT07493538RecruitingPhase 2
Blood stem cell transplant with lower-intensity chemo for blood cancers
This trial tests a stem cell transplant using milder chemotherapy (treosulfan and fludarabine) followed by a drug called cyclophosphamide to prevent graft-versus-host disease. It aims to make transplant safer for people with blood diseases who cannot handle standard high-dose chemotherapy.
Minneapolis, MinnesotaAges 2–75
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 401 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.