Advanced or Metastatic Breast Cancer clinical trials

Safety study of GenSci140 for advanced solid tumors

This trial tests a new drug, GenSci140, for people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and how well it works.

Study of GenSci143 for advanced solid tumors

This trial tests a new drug, GenSci143, for people with advanced solid tumors that have stopped responding to standard treatments. It may be an option if your cancer has spread or come back and you have no other standard options left.

Study of WJ22096 tablets for advanced solid tumors

This trial tests a new oral drug (WJ22096) for people with advanced solid tumors that have stopped responding to or cannot tolerate standard treatments. It may be an option if you are generally healthy enough to take part.

Implantable chip to test chemo in pancreatic cancer surgery

This trial tests a tiny implantable device that measures how different chemotherapy drugs work on your tumor during surgery. The goal is to find the most effective treatment for your specific cancer.

Comparing lung biopsy methods for suspected lung cancer

This study compares two ways of doing a lung biopsy with a needle guided by ultrasound. It aims to see which method gives better samples for diagnosing lung cancer.

A study of QLC5508 combinations for advanced solid tumors

This trial tests a new drug called QLC5508, given in combination with other treatments, for people with advanced solid tumors that have stopped responding to standard therapy or who haven't had treatment yet. The goal is to see if the combination can shrink tumors or slow their growth.

CEL001 injection safety study for advanced solid tumors

This trial tests a new injection called CEL001 for people with advanced solid tumors that have not responded to or cannot tolerate standard treatments. The goal is to see if it is safe and find the right dose.

Immunotherapy before surgery for localized cancers

This trial tests immunotherapy before surgery for people with localized solid tumors. It aims to improve how well the cancer is controlled and may help shrink tumors so they can be removed more easily.

Tumor testing to guide treatment for advanced cancers

This trial uses a patient's own tumor tissue to test which drugs might work best for cancers that have returned or not responded to previous treatments. It focuses on advanced gastric cancer and other solid tumors.

Testing BTM-3566 for advanced solid tumors

This trial tests a new drug, BTM-3566, for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective.

Study of a new drug (OTP-01) for advanced solid tumors

This trial is testing a new drug called OTP-01 that targets two proteins (PD-1 and VEGFR2) to help your immune system fight cancer and stop tumors from growing. It is for people with advanced solid tumors that have not responded to or cannot have standard treatments.

Tuvonralimab and Iparomlimab Based Regimens for the Neoadjuvant Treatment of Biliary Tract Cancer

JMT106 for advanced solid tumors

This trial is testing a new medicine called JMT106 for people with advanced solid tumors (cancers that have spread or can't be removed). It's for patients whose cancer has not responded to or can't use other treatments, and who have not had a therapy targeting a specific protein (GPC3) before.

Study of a targeted radiation therapy for small cell lung cancer

This trial tests a new drug called MP0712 that delivers radiation directly to cancer cells that have a marker called DLL3. It is for people with small cell lung cancer or other solid tumors that express DLL3, whose cancer has come back after prior treatments.

Coping help for ovarian cancer care providers

This trial tests a program to help doctors, nurses, and other clinicians who care for ovarian cancer patients manage burnout and stress. It aims to see if the adapted coping intervention improves well-being.

Study of ONC206 for advanced pheochromocytoma and paraganglioma

This trial tests an oral drug called ONC206 (JZP3507) for people with advanced pheochromocytoma or paraganglioma that cannot be removed with surgery. It may be an option if you've already tried standard treatments or cannot take them.

JS107 vs standard therapy for advanced stomach cancer

This trial tests a new drug, JS107, against standard treatments for people with advanced stomach or gastroesophageal junction cancer that has continued to grow after at least one prior treatment. The cancer must have a specific protein called CLDN18.2 on its cells.

TTFields and chemo for metastatic pancreatic cancer

This trial tests a wearable device (TTFields) combined with a specific chemotherapy (mFOLFIRINOX) for people whose pancreatic cancer has spread to the liver and other organs. The device sends gentle electrical fields to disrupt cancer cell growth, and the chemo attacks cancer cells throughout the body.

Study on sleep and advanced Parkinson's with foslevodopa/foscarbidopa

This study looks at how a Parkinson's drug delivered under the skin (foslevodopa/foscarbidopa) affects sleep problems in people with advanced Parkinson's. It is a real-world study that follows your usual treatment, no new experimental drug is being tested.

Study of AT1019 with radiation and immunotherapy for advanced solid tumors

This trial tests a new drug called AT1019 given together with targeted radiation (SBRT) and an immunotherapy drug for people with advanced solid tumors that are already being treated with immunotherapy. It aims to see if this combination can shrink or control tumors better.

Study of JSKN022 for advanced solid tumors

This trial tests a new drug, JSKN022, for people with advanced solid tumors that have stopped responding to standard treatments or are not eligible for them. The goal is to see if the drug is safe and effective.

Precision radiation to protect erectile function in prostate cancer

This trial tests a new radiation technique to better protect erectile function during prostate cancer treatment. It uses advanced imaging to precisely target the tumor while reducing harm to nearby structures.

An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors

Study of VBC103 for advanced solid tumors

This trial tests a new drug, VBC103, for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug can shrink or slow the growth of these tumors.