Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07070076Recruiting
Y-90 therapy vs chemo infusion for liver cancer
This study compares two liver-directed treatments—radioactive Yttrium-90 beads (SIRT) and a type of chemo infusion directly into the liver (HAIC)—for people whose liver cancer is advanced enough to need treatment but might still be removable with surgery. The goal is to see which approach can shrink the tumor best before surgery.
Guangzhou, GuangdongAges 18–75 - NCT07070700RecruitingPhase 2
Cryoablation with targeted therapy and immunotherapy for advanced bile duct cancer
This trial tests a combination of cryoablation (freezing tumors), lenvatinib (a targeted therapy), and QL1706 (an immunotherapy) for people with advanced intrahepatic cholangiocarcinoma (bile duct cancer) that has worsened after initial treatment. The goal is to see if this combination can help stop the cancer from growing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07085169RecruitingPhase 2
Low-dose chemo combo for advanced colorectal cancer
This trial tests a lower dose of a chemotherapy pill (trifluridine/tipiracil) combined with bevacizumab for advanced colorectal cancer that has not responded to at least two prior treatments. The goal is to see if this combination can help control the cancer with fewer side effects.
SanmingAges 60 years+ - NCT07086469RecruitingPhase 2
Surufatinib plus chemo-immunotherapy before chemoradiation for advanced esophageal cancer
This trial tests a new combination of treatments for people with advanced esophageal cancer that can't be removed by surgery. It uses a targeted therapy called surufatinib along with chemo-immunotherapy and radiation to see if it can shrink the tumor before further treatment.
Guangzhou, GuangdongAges 18–80 - NCT07091981Recruiting
Effect of file count on MB2 canal access and post-treatment pain
This trial tests whether using different numbers of rotary files affects the ability to find and clean a small extra canal (MB2) in upper first molars and how much pain patients feel afterward. It may help dentists choose a better treatment approach.
Antakya, HatayAges 20–65 - NCT07099027Recruiting
Lung Health Check Pilot For Smokers Aged 55-74
This study is a lung health check pilot to find lung cancer early in people who are at higher risk because of their age and smoking history. You will get a free, low-dose CT scan to check for any signs of lung cancer.
DublinAges 55–74 - NCT07100405Recruiting
TACE plus Immunotherapy for Advanced Liver Cancer
This trial tests a combination of two treatments for advanced liver cancer: TACE (a procedure that blocks the blood supply to the tumor) and an anti-PD-1 antibody (a type of immunotherapy that helps your immune system fight cancer). The goal is to see if this combination works better than either treatment alone and to understand how it affects the immune system around the tumor.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07105748RecruitingPhase 2
HAIC plus Camrelizumab and Rivoceranib for advanced mixed liver-bile duct cancer
This trial tests a combination of three treatments for a rare form of liver cancer that is both hepatocellular and cholangiocarcinoma: HAIC (chemotherapy given directly into the liver artery), Camrelizumab (an immunotherapy that helps your immune system attack cancer cells), and Rivoceranib (a targeted therapy that blocks blood vessel growth to tumors). It may be an option if you haven't had prior systemic therapy for this cancer and your liver function is stable.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07105852RecruitingPhase 2
A new drug combo for advanced bile duct cancer
This trial tests a combination of two drugs, sacituzumab tirumotecan and pucotenlimab, for people with advanced bile duct cancer (including gallbladder cancer) that cannot be removed by surgery or has spread. The goal is to see if this treatment is safe and works well, especially for those with a protein called TROP2 on their cancer cells.
Hangzhou, ZhejiangAges 18 years+ - NCT07112222RecruitingPhase 1/Phase 2
Study of LM-350 for advanced solid tumors
This trial tests an experimental drug called LM-350 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if the drug can shrink tumors or slow their growth.
Wollongong, New South WalesAges 18 years+ - NCT07114770Recruiting
Theta Burst Stimulation for Autism in Adults
This study tests whether a painless brain stimulation technique called theta burst stimulation (TBS) can help autistic adults when applied to the cerebellum. The goal is to see if one session or multiple sessions improve symptoms.
TaoyuanAges 18 years+ - NCT07121036RecruitingPhase 1
High-dose vitamin C infusion for advanced solid tumors
This trial tests a special high-dose vitamin C infusion, given based on how your body processes it, for people with advanced solid tumors. It aims to see if this vitamin C therapy can be safely combined with your current or new chemotherapy to help control the cancer.
Wuhan, HubeiAges 18–75 - NCT07126509Recruiting
Surgery for pleural mesothelioma that cannot be fully removed
This trial tests if a partial surgery called pleurectomy can help people with a specific type of mesothelioma that cannot be fully removed. You must have already completed at least 6 weeks of chemotherapy or immunotherapy without the cancer growing.
Chicago, IllinoisAges 18 years+ - NCT07126678Recruiting
Zanubrutinib, Bendamustine, and Obinutuzumab for advanced follicular lymphoma
This trial tests a 3-drug combination (Zanubrutinib, Bendamustine, and Obinutuzumab) for people with advanced follicular lymphoma who have not had treatment before. The goal is to see if a fixed-duration treatment plan can improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT07128641RecruitingPhase 2
Odronextamab for early follicular lymphoma without prior treatment
This trial tests a new immunotherapy drug, odronextamab, for people with slow-growing follicular lymphoma that hasn't been treated yet and isn't causing big problems. It aims to see if the drug can control the cancer with fewer side effects.
Boston, MassachusettsAges 18 years+ - NCT07134842RecruitingPhase 1
Immunotherapy before standard brain cancer treatment
This trial tests giving the immunotherapy drug ipilimumab before the usual treatment for newly diagnosed glioblastoma (a type of brain cancer). The goal is to see if this approach is safe and possible, and whether it might help the immune system fight the tumor better.
London, Greater LondonAges 18 years+ - NCT07137754Recruiting
Physiotherapy for minor injuries in the emergency department
This study tests whether a physiotherapy-led care model in the emergency department can help people with minor muscle or bone injuries recover better and at a lower cost. If you join, you'll see a physiotherapist instead of a doctor for your arm or leg injury.
Aarhus NAges 18 years+ - NCT07141121Recruiting
Testing a new imaging tool during prostate removal surgery
This study tests if a special microscope called confocal laser endomicroscopy can help doctors check for leftover cancer cells faster during prostate removal surgery. It is for patients with intermediate or high-risk prostate cancer who are scheduled for robot-assisted prostate removal and have not had prior treatment.
New York, New YorkAges 18 years+ - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07152249Recruiting
Improving nausea and vomiting care during surgery
This trial tests a new approach to prevent nausea and vomiting after surgery. It compares usual care to a structured plan that matches anti-nausea medicines to your personal risk factors.
Nashville, TennesseeAges 18 years+ - NCT07152678RecruitingPhase 2
Brachytherapy with radiation and immunotherapy for esophageal cancer
This trial tests combining brachytherapy (a type of internal radiation) with immunotherapy (nivolumab) for people with advanced esophageal cancer that has not fully responded to initial chemoradiation. The goal is to see if this targeted approach can improve outcomes.
Huwei, Yunlin CountyAges 18–85 - NCT07155226RecruitingPhase 1/Phase 2
Study of AZD3632 for advanced blood cancers with certain gene changes
This trial is testing a new drug, AZD3632, either alone or with other cancer treatments, for people with advanced blood cancers that have specific genetic changes (like KMT2Ar, NPM1m, or others that cause HOX over-expression). The goal is to see if it can help when standard treatments have stopped working.
Decatur, IllinoisAges 16 years+ - NCT07156565RecruitingPhase 1
Targeted radiation therapy for advanced sarcoma
This trial tests a new radioactive drug for people with advanced soft tissue sarcoma that has come back or not responded to prior treatment. The drug targets a protein found on sarcoma cells to deliver radiation directly to the tumor.
Los Angeles, CaliforniaAges 18 years+ - NCT07157969RecruitingPhase 2
Immunotherapy and anti-VEGF with or without local therapy for liver cancer
This trial tests a combination of immunotherapy (checkpoint inhibitors) and anti-VEGF therapy (which blocks blood vessel growth to tumors) with or without local treatments (like chemoembolization) for advanced liver cancer. It aims to see if the combination works better than current treatments.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,192 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.