Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07679906Recruiting
Nationwide digital study for Alzheimer’s prevention and trial readiness
This study uses a saliva sample and online tools to see if you have a genetic risk factor for Alzheimer’s. It aims to build a large group of people who may be at higher risk, so they can be invited to future prevention trials.
HuningueAges 45 years+ - NCT02414178Enrolling by invitation
Tau PET brain scan for inherited Alzheimer’s disease
This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.
St Louis, MissouriAges 18 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT06230783Recruiting
Speech test for early Alzheimer's detection
This trial uses speech pattern analysis to detect early signs of Alzheimer's. If you're already in a Wisconsin Alzheimer's study, you may help test if your voice can reveal memory changes.
Madison, WisconsinAges 40–80 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT06953167Recruiting
Dementia study for older adults with prior brain checks
This study follows older adults who have already had amyloid testing, to track changes in memory and thinking over time. It helps researchers understand how to prevent dementia.
LondonAges 65 years+ - NCT05048966Recruiting
Comparing two wellness support groups for brain injury and dementia
This study compares two group wellness programs for people with brain injuries or dementia and their caregivers. It aims to see which program helps improve well-being and quality of life for both the person with the condition and their support person.
East Hanover, New JerseyAges 18 years+ - NCT06784830Recruiting
Nursing care for Alzheimer's patients during PET/CT scans
This trial tests a special nursing care plan for Alzheimer's patients during PET/CT brain scans. The goal is to make the imaging experience more comfortable and safe for people with memory loss.
Chengdu, SichuanAges Any age - NCT05806697Recruiting
Study of brain scan clues in people worried about memory
This extension study looks for predictors—measurable clues—linked to memory changes in older adults who feel their memory is worsening. You may be asked to have an amyloid PET scan, which can help researchers understand what might be driving memory concerns.
Paris, Île-de-France RegionAges 70–95 - NCT05456503RecruitingPhase 3
PET scan study of tau buildup in memory and brain disorders
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06801639Recruiting
Brain stimulation at home for mood symptoms in Alzheimer's
This study tests if a gentle brain stimulation technique, called tDCS, can help improve mood symptoms like depression, anxiety, or irritability in people with Alzheimer's or mild cognitive impairment. A caregiver will help with the sessions at home, and all visits are done remotely.
San Antonio, TexasAges 60–85 - NCT07234851Enrolling by invitation
Brain tissue study of synaptic loss in mental and brain diseases
This study looks at how brain connections break down in people with psychiatric disorders (like schizophrenia, depression, or bipolar disorder) or neurodegenerative diseases (like Alzheimer's or frontotemporal dementia). It uses donated brain tissue after death to understand why symptoms occur.
BarcelonaAges 40 years+ - NCT06164262Recruiting
Dementia risk study for people with small vessel disease
This study tracks people ages 30 to 60 who have signs of small vessel disease on brain MRI. It aims to understand the risk of dementia over the next 10 years, so you can get early monitoring and care.
Hangzhou, ZhejiangAges 30–85 - NCT02564692Enrolling by invitation
APOE gene testing registry to find Alzheimer’s prevention studies
This program enrolls people to get a gene test (APOE) so researchers can match you to Alzheimer’s prevention studies in the future. If you qualify, you do the test but you would not receive your gene test results.
Phoenix, ArizonaAges 50–90 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT04524338Recruiting
At-home brain stimulation study for dementia
This study looks at using a home device that delivers a mild electrical current to the brain (“tDCS”) over time in people with Alzheimer’s disease or other dementias. It aims to learn whether this approach is safe and potentially helpful for symptoms.
Montreal, QuebecAges 50–100 - NCT07465783Recruiting
Music therapy for sleep and calm in dementia care
This study tests whether a music therapist working one-on-one with people who have dementia can help them fall asleep better and stay calmer during the day. It takes place in a locked dementia care unit.
Saint-EtienneAges 60 years+ - NCT07425106Enrolling by invitation
Comparing a low-cost eye scanner for Alzheimer's research
This study uses a special, low-cost eye scanner to look at the back of the eye (retina) in people with early Alzheimer's or mild memory problems. It aims to find changes that might help with early detection.
Durham, North CarolinaAges 18–85 - NCT07413744RecruitingPhase 1
Gut health and probiotics study for memory concerns
This study looks at how a probiotic supplement affects the gut and thinking in older adults, including those with mild cognitive impairment or Alzheimer's. It may help explain if improving gut health can support brain health.
Madison, WisconsinAges 60 years+ - NCT07392723RecruitingPhase 2
Flaxseed nutrition to protect memory in APOE4 adults
This study tests a special flaxseed-based nutrition drink to see if it can slow memory loss in older adults who have the APOE4 gene and mild cognitive impairment (early memory trouble). If you qualify, you'll take the drink daily for a year and have memory tests and brain scans.
New Brunswick, New JerseyAges 60 years+ - NCT07353502Recruiting
Early Alzheimer's brain connection study
This study looks at a specific brain pathway that may be linked to early memory loss in Alzheimer's disease. It compares people with early Alzheimer's to healthy older adults to understand how connections between brain cells start to break down.
Yiwu, ZhejiangAges 50 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 471 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.