Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07279740RecruitingPhase 2
Brain stimulation plus medication for apathy in dementia
This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.
Toronto, OntarioAges Any age - NCT07239843Enrolling by invitation
Study of blood markers and mental health in brain diseases
This study looks at how social factors and blood markers relate to psychiatric symptoms in people with brain diseases or mental disorders. It aims to find new ways to understand and diagnose these conditions.
Barcelona, BarcelonaAges 18 years+ - NCT07234695RecruitingPhase 3
Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's
This trial tests if levetiracetam, a seizure medication, can prevent seizures in adults with Down syndrome who also have Alzheimer's disease. It aims to help manage a common complication and improve quality of life.
Granada, AndalusiaAges 40 years+ - NCT07235111Recruiting
Studying biomarkers for neurodegenerative diseases
This study is looking for people with neurodegenerative diseases (like Alzheimer's, Parkinson's, ALS) to help researchers find new markers in the body that could help understand these conditions better and possibly lead to better treatments.
Genoa, GenoaAges 18 years+ - NCT07222280Recruiting
Alzheimer's dementia and brain inflammation trial
This trial tests if treating brain inflammation can help older adults hospitalized with sudden confusion or cognitive issues. It may help those without a prior dementia diagnosis but who have toxic or metabolic causes for their symptoms.
Crossville, TennesseeAges 60–90 - NCT07222605Enrolling by invitation
MemorEM device study for brain diseases
This study tests a device called MemorEM to see how it works for people with brain diseases that cause memory and thinking problems (like Alzheimer's, Parkinson's, and ALS). It aims to understand your experience with the device.
Atlanta, GeorgiaAges 45–100 - NCT07213700Recruiting
Alzheimer's disease long-term study
This study follows people with Alzheimer's disease over time to learn more about the condition and improve future care. It is an observational study, meaning participants receive their usual care while researchers collect information.
MelbourneAges 18 years+ - NCT05374278RecruitingPhase 1/Phase 2
PET scan test for a dementia brain tracer
This early-phase study tests a new PET scan tracer that targets a brain chemical transport system involved in dementia. It aims to see if the tracer can safely and clearly show brain changes, which could help future dementia diagnosis or tracking.
San Francisco, CaliforniaAges 40–75 - NCT07182357Recruiting
Improving hospice transitions for advanced dementia
This study looks at how to improve the transition to hospice care for people with advanced dementia and their care partners. It will interview care partners and healthcare professionals to design better care management.
New York, New YorkAges 18 years+ - NCT07158905RecruitingPhase 1
Tau vaccine study for early Alzheimer's prevention
This study tests a vaccine that targets tau protein, which is linked to Alzheimer's disease. It is for older adults who have no memory problems yet but have biological signs of early Alzheimer's, to see if the vaccine can prevent or slow down the disease.
Boca Raton, FloridaAges 65–80 - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07143734RecruitingPhase 2
Brain stimulation for early Alzheimer's disease
This study tests a new, noninvasive brain stimulation method called Transcranial Pulse Stimulation (TPS) for people in the early stages of Alzheimer's disease. The goal is to see if it can help improve symptoms.
Hong KongAges 60–90 - NCT07049341Enrolling by invitation
A pilot trial of the MemorEM device for neurological diseases
This trial tests a device called MemorEM to see how patients with neurological diseases like Alzheimer's or Parkinson's experience it. It aims to understand if the device is comfortable and easy to use.
Tampa, FloridaAges 45–100 - NCT07036328Recruiting
Magnetic brain stimulation to slow memory loss in Alzheimer's
This study tests whether a noninvasive magnetic brain stimulation treatment can slow down cognitive decline in people with early Alzheimer's disease. You'll receive daily sessions over several weeks, and the goal is to see if it helps preserve memory and thinking skills.
AmsterdamAges 50–85 - NCT07027072RecruitingPhase 2
Testing KDS2010 for early Alzheimer's memory loss
This study tests a new drug called KDS2010 for people with early Alzheimer's or mild memory loss. It aims to see if the drug can slow thinking and memory decline. You will need a caregiver to help with visits and must have a special brain scan showing amyloid plaques.
Gwangju, GwangjuAges 50–85 - NCT06996730RecruitingPhase 2/Phase 3
Study of donanemab and RG6289 for genetic Alzheimer's disease
This trial tests two medications (donanemab and RG6289) alone or together in people who carry a specific genetic mutation (PSEN1 E280A) that causes early-onset Alzheimer's disease. It aims to see if these drugs can slow or prevent memory loss.
Medellín, AntioquiaAges 25–65 - NCT06965062Recruiting
Neck surgery for Alzheimer's: a first test
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
SingaporeAges 50–80 - NCT06936514Enrolling by invitation
Lymphatic surgery for Alzheimer's: a clinical study
This trial tests a surgery that targets the lymphatic system in the neck to help people with moderate-to-severe Alzheimer's disease. The goal is to see if it can improve cognitive function.
TianjinAges 50–80 - NCT06922188Recruiting
Screening for financial hardship in Alzheimer's and dementia
This study aims to develop a way to measure financial hardship in people with Alzheimer's disease, related dementias, and their caregivers. By taking part, you can help create a tool that may identify financial struggles and connect families with needed support.
Seattle, WashingtonAges 18 years+ - NCT06880406Recruiting
Study of cell energy in Alzheimer's and other dementias
This study looks at how energy production in cells (mitochondria) differs in people with Alzheimer's or other dementias compared to healthy volunteers. It involves a one-time spinal tap to collect fluid for analysis.
Nice, PACAAges 18 years+ - NCT06875986Recruiting
Study of REXULTI for agitation in Alzheimer's disease
This trial is studying how a medication called REXULTI works in patients with Alzheimer's disease who have symptoms like excessive activity, aggression, or mood swings. It aims to see if the drug helps manage these behaviors.
Osaka, OsakaAges 15 years+ - NCT06862557Recruiting
PEMF treatment for people with dementia
This study tests whether a pulsed electromagnetic field (PEMF) device can help people with mild to moderate Alzheimer's or related dementias. If you or a loved one has memory loss, this trial looks at a potential new way to support brain health without medication.
Boca Raton, FloridaAges 50–100
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 471 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.