Clinical trials
Aortic Stenosis clinical trials
Below are recruiting aortic stenosis clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06008080Recruiting
Study following patients after Navitor valve implant
This study is checking how well the Navitor heart valve works in real-world patients. If you are scheduled to get this valve, you may be able to join.
AdelaideAges 18–100 - NCT07193888Recruiting
Navitor valve study for aortic stenosis
This study is testing the Navitor valve, a device to replace a narrowed aortic heart valve without open-heart surgery. It will track how well the valve works in people who are already good candidates for this procedure.
FukuokaAges 18–100 - NCT02023060Recruiting
Improving function and quality of life after heart valve repair
This study looks at how a less invasive heart valve procedure affects your day-to-day functioning and overall quality of life. If you’re already being considered for a transcatheter (catheter-based) valve replacement, you may be able to join to help understand what improvements patients experience.
JerusalemAges 18–110 - NCT06493994Recruiting
Looking at Myval valve placed through the armpit
This study collects information on people who have already received a new aortic valve through a small cut in their armpit using the Myval valve. Doctors want to see how well this approach works over time.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04414865Recruiting
Check a new heart valve treatment for older, high-risk patients
This study follows how the VitaFlow heart valve works in people age 70+ who have severe, narrowed aortic valves and cannot safely get open-heart valve surgery. It’s meant to see whether the device improves outcomes and is safe over time.
Shanghai, Shanghai MunicipalityAges 70 years+ - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT06557798Recruiting
Second TAVI for failing aortic valve replacement
This trial is for people who have already had a TAVI (a minimally invasive aortic valve replacement) and now need a second procedure because the valve is failing. The study will test how well a redo TAVI works to fix the failing valve.
AalborgAges 18 years+ - NCT06507579Recruiting
Aortic stenosis valve replacement study with Hydra device
This trial tests a new heart valve called Hydra for people with severe aortic stenosis who need a valve replacement through a leg artery. It aims to see how well the valve works in real-world patients.
Sheffield, YorkshireAges 18–99 - NCT06342635Recruiting
Study of Hydra Heart Valve in Copenhagen
This study is testing a new heart valve system called Hydra, used during a less invasive procedure called TAVI to replace a narrowed heart valve. It may help people with severe aortic stenosis who are already candidates for TAVI.
CopenhagenAges 18–99 - NCT06818435Recruiting
Registry study of the Myval heart valve for severe aortic stenosis
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
CarnaxideAges 18 years+ - NCT07350629Recruiting
Checking heart valve disease with a finger sensor
This study uses a finger sensor to measure artery waves to assess heart valve problems like aortic regurgitation or stenosis. If you have one of these conditions or are a healthy volunteer, you may help improve noninvasive heart disease detection.
Hefei, AnhuiAges 18–80 - NCT06753227Enrolling by invitation
Comparing ways to measure valve pressure after TAVI
This trial looks at how well a new method (using echo) compares to the standard invasive method for measuring pressure across the new valve after TAVI. It may help doctors monitor your valve function with less risk.
Munich, BavariaAges 18 years+ - NCT05172973Recruiting
New valve procedure for failing aortic bioprosthetic valves
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
Newport Beach, CaliforniaAges Any age - NCT06768008Recruiting
Integrated care model for newborns with critical heart disease
This trial tests a coordinated treatment plan for newborns with critical congenital heart disease, starting before birth and continuing after delivery. It aims to improve outcomes for babies who need two-ventricle repair surgery.
BeijingAges 1 day–4 weeks - NCT07752732Recruiting
Heart scans for amyloidosis in people with severe aortic valve stenosis
This study looks at how often cardiac amyloidosis occurs in people with severe aortic valve stenosis. It uses different heart scans to find out more. If you have both conditions, this research may help doctors understand your situation better.
TübingenAges 18 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06535659Recruiting
VitaFlow Liberty Valve Study for Severe Aortic Stenosis
This trial tests a new valve replacement device (VitaFlow Liberty) that is inserted through a tube in an artery, avoiding open-heart surgery. It is for people with severe aortic stenosis who are at high risk for traditional surgery.
GalwayAges 18 years+ - NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90 - NCT07045233Enrolling by invitation
Using a brain protection device during TAVR to prevent stroke
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
BeijingAges 18 years+ - NCT04227002Recruiting
Study for people with aortic valve problems
This trial is for people with aortic valve disease (aortic valve narrowing, leakage, or a worn-out valve). It tests what the doctors learn from following these patients, and it may help improve future care.
HamburgAges 18 years+ - NCT05788770Recruiting
CT scan and computer planning before TAVR valve replacement
This study uses a CT scan plus a personalized computer model to plan a less invasive valve replacement (TAVR). It may help doctors better prepare for the procedure using simulation before your valve is placed.
ViennaAges 18 years+ - NCT01805739Recruiting
Imaging tests for people before aortic valve replacement
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07359898Recruiting
Study of a new heart valve for aortic stenosis
This study is testing a new type of heart valve (Navitor or Navitor Vision) for people with aortic stenosis. The valve is placed without open-heart surgery, and the goal is to see how well it works in a real-world setting. If you've already been recommended for this procedure by your heart team, you may be able to join.
San Donato Milanese, LombardyAges 18 years+ - NCT04636684Recruiting
Study ATTR deposits in the aortic valve
This study looks at how common ATTR-related protein deposits are in the heart valve of people with age-related (degenerative) aortic stenosis. It may help doctors understand how important these deposits are and could guide future treatment decisions.
ToulouseAges 18–99
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Common questions
- Are there clinical trials for aortic stenosis?
- Yes. Clin2 currently lists 208 recruiting aortic stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.