Clinical trials
Aortic Stenosis clinical trials
Below are recruiting aortic stenosis clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06168370Recruiting
Personalized blood thinners after TAVI vs. standard care
This trial tests whether a personalized plan for blood thinners after TAVI can reduce the risk of stroke or bleeding better than the current standard of one daily blood thinner. If you've had a successful TAVI and don't need specific other blood thinners, you might be able to join.
NieuwegeinAges 18–110 - NCT05603026Recruiting
MRI study for people getting a valve replacement
This study uses MRI (a type of scan) in people who are scheduled for a catheter-based aortic valve replacement through the groin. It aims to see how well MRI can work for these patients and potentially improve care planning around the procedure.
Cleveland, OhioAges 18–105 - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT06602609Recruiting
Remote heart monitoring after TAVI valve procedure
This trial tests whether patients can go home the same day after TAVI and use a smart device for remote monitoring. It aims to see if this approach is safe and effective for recovery.
LondonAges 18 years+ - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+ - NCT07107568Recruiting
Testing ways to check heart arteries before valve replacement
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
InnsbruckAges 18 years+ - NCT07309029Recruiting
ECMO support during high-risk TAVR heart valve procedure
This trial tests whether placing patients on ECMO (a heart-lung support machine) before a high-risk TAVR valve replacement can improve safety and outcomes. It is for people who are at very high risk due to low blood pressure, severe heart or lung problems, or complex valve anatomy.
Detroit, MichiganAges 18–100 - NCT06861361Recruiting
Surgery versus transcatheter valve replacement in younger patients
This trial compares two ways to replace a narrowed aortic heart valve in patients aged 65 to 75. It aims to find which approach—surgical valve replacement or a catheter-based procedure—works better for people in this age group.
GrazAges 65–75 - NCT05758662Recruiting
PET-CT and heart ultrasound study valve changes after TAVI
This study looks at whether certain valve blood clots (called “subclinical leaflet thrombosis”) and different valve types are linked to valve aging over time. It uses a special PET-CT scan and an echocardiogram to measure changes in the heart valve about five years after TAVI.
CopenhagenAges 18 years+ - NCT07596394Recruiting
Registry of Catheter-Based Aortic Valve Replacements
This registry collects information about patients who receive a new valve inserted through a catheter (a thin tube) rather than open surgery. It tracks how well the procedure works and any side effects to help doctors understand the long-term safety and effectiveness of this less invasive approach.
Pavia, PaviaAges 18 years+ - NCT06991517Recruiting
TAVR sizing study for bicuspid aortic valve patients
This study tests a special sizing method (ABC algorithm) to help doctors select the right valve for people with a bicuspid aortic valve. It aims to improve outcomes for those getting a Sapien 3 valve through a catheter (TAVR).
St Leonards, New South WalesAges Any age - NCT04552275RecruitingPhase 1
Biomarker study during valve replacement for older adults
This Phase 1 study looks at changes in the body’s “biomarkers” (measurable signs in blood/medical tests) in older people who are getting a specific type of valve replacement. Results may help doctors better monitor or understand outcomes after this valve procedure.
Boston, MassachusettsAges 65 years+ - NCT06129799Recruiting
Exercise heart MRI for low-flow aortic stenosis
This trial uses a special heart MRI scan before and after exercise to study blood flow in people with a type of aortic stenosis where the heart's pumping function may be reduced. It could help doctors better understand how to treat this condition.
GöttingenAges 18 years+ - NCT06756282Recruiting
Pacemaker use one year after TAVR
This study looks at people who need a permanent pacemaker after having a TAVR procedure (a type of heart valve replacement). It aims to see how many people still need the pacemaker one year later.
MontpellierAges Any age - NCT05866640RecruitingEarly Phase 1
Testing a filter to reduce debris during TAVR
This early feasibility study tests a device filter system used during a TAVR procedure to help protect the brain and other organs from debris that can break free. It looks mainly at whether the filter can be safely placed and delivered as planned.
TbilisiAges 22 years+ - NCT07343674Recruiting
Studying a new heart valve replacement system for aortic stenosis
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07240025Enrolling by invitation
TAVR outcomes for small aortic valves in Asian patients
This study looks at how well a minimally invasive heart valve replacement (TAVR) works for Asian patients with a small aortic valve opening. It aims to understand what affects the results.
Hong Kong, ShatinAges Any age - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT07205068Recruiting
Shockwave treatment for TAVR access site
This trial tests if using Shockwave IVL to break up calcium in the groin artery before a TAVR procedure can improve outcomes. It may help patients with significant calcium buildup at the access site.
Knoxville, TennesseeAges 18 years+ - NCT07194265Recruiting
A study of the DurAVR heart valve for aortic stenosis
This trial tests a new heart valve called DurAVR for people with severe aortic stenosis (a narrowed aortic valve) who need a valve replacement. It compares the new valve to standard valves to see if it is safe and works well.
Copenhagen, Capital Region of DenmarkAges 18 years+ - NCT07035847Recruiting
Transaxillary TAVR guided by ultrasound only
This trial is testing a new way to replace your aortic valve using a small tube through your armpit, guided only by ultrasound (echocardiography) instead of X-rays. It may be an option if you have severe aortic stenosis and are a good fit for this less invasive approach.
Beijing, Beijing MunicipalityAges Any age - NCT07006064Recruiting
Comparing oxygen methods during TAVI for older patients
This trial tests a new oxygen device (SuperNO2VA) against standard oxygen to prevent low oxygen levels in patients aged 65 and older who are getting a heart valve procedure (TAVI) while sedated. The goal is to see which method keeps oxygen levels safer.
AnkaraAges 65 years+ - NCT06911463Enrolling by invitation
Pain relief for TAVI valve procedure
This study tests two numbing injections for people having a new aortic valve placed through a leg artery (TAVI). One injection is near the hip bone, the other in the groin area. The goal is to see which one provides better pain control while keeping you awake and comfortable.
CairoAges 20 years+ - NCT06891079Enrolling by invitation
Guiding TAVI with a new angiographic method
This study tests a new way to use X-ray images during a TAVI procedure to check how well the new valve is working right away. It may help doctors make real-time adjustments to improve the outcome.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for aortic stenosis?
- Yes. Clin2 currently lists 198 recruiting aortic stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.