Clinical trials
Aphasia clinical trials
Below are recruiting aphasia clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04957537Recruiting
Speech and meaning therapy for primary progressive semantic aphasia
This study tests a “semantic rehabilitation” program—therapy focused on improving word meaning and understanding—for people with primary progressive semantic aphasia. If you qualify, it may help slow or improve language difficulties and daily communication.
ToulouseAges 18–100 - NCT04742894Recruiting
EEG and MRI study of speech problems after stroke
This study looks at brain activity during speech tasks to better understand why some people with aphasia have trouble coordinating speech. It compares people with long-term (chronic) left-stroke aphasia to healthy volunteers, using EEG and MRI.
Irvine, CaliforniaAges 21–75 - NCT04682223Recruiting
Online speech therapy for people with stroke-related aphasia
This study tests whether telerehabilitation (therapy done by video/remote technology) can improve communication after a stroke caused aphasia. It may help you practice speech and understanding skills at home or from a convenient location.
Columbia, South CarolinaAges 21–80 - NCT04375722Recruiting
Brain stimulation study for language problems after stroke
This trial tests whether gentle, noninvasive brain stimulation (tACS) can improve speech and language (aphasia) after stroke. You may be asked to do language and thinking tests before and after the stimulation to see if it helps.
Milwaukee, WisconsinAges 18–85 - NCT04433351Recruiting
Rehab training to improve speech after stroke in French speakers
This trial studies a sensory-and-movement training approach to help people relearn speech after stroke-related language difficulties. It may help if your type of post-stroke aphasia is mainly non-fluent and you can safely complete brain scans.
GrenobleAges 55–75 - NCT04432883Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests whether targeted mild brain stimulation (tDCS) can improve speech therapy results for people with long-lasting (chronic) aphasia after a stroke. It may help strengthen naming and communication when added to standard speech-language treatment.
Albuquerque, New MexicoAges 25–85 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT03887481Recruiting
Brain stimulation study for a language-loss dementia subtype
This trial tests whether a painless form of brain stimulation can improve language and thinking skills in people with the logopenic variant of primary progressive aphasia (a dementia that affects language). You may receive brain stimulation along with repeated clinic visits to track changes over time.
Baltimore, MarylandAges 50–80 - NCT03843463RecruitingPhase 2
Escitalopram plus language therapy after left stroke
This trial tests whether the antidepressant medicine escitalopram, along with language therapy, can improve language skills after a recent stroke that affected the left side of the brain. It may help some people with stroke-related aphasia (language difficulty) regain words and communication.
Baltimore, MarylandAges 18–99 - NCT00537004Recruiting
Study of language in primary progressive aphasia
This study looks at how language changes in people with primary progressive aphasia. It may help researchers better understand the condition and how it affects speech and communication over time.
Chicago, IllinoisAges Any age - NCT05891873Recruiting
Study delirium during ICU care for stroke patients
This study looks at “delirium,” a sudden confusion that can happen during critical care, in people receiving ICU treatment for stroke. It includes both adults and children in specific ICU settings and may help clinicians better prevent or manage confusion during recovery.
BrnoAges Any age - NCT07798700Recruiting
Biofluid research for brain and movement disorders
This study collects blood, spinal fluid, and other samples from people with brain or movement disorders, their family members, and healthy volunteers. The goal is to find better ways to diagnose and understand these conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07739875Recruiting
App-based therapy for post-stroke word-finding
This trial tests a therapy delivered through a smartphone app to help people with aphasia (trouble finding words after a stroke) improve their ability to name things. The therapy happens in daily life, not in a clinic, and is personalized to the words you need most.
Boston, MassachusettsAges 18–89 - NCT07650188Recruiting
Brain Stimulation to Help Aging Memory and Thinking
This study tests whether brain and sensory stimulation can help people with early memory loss or mild cognitive changes. Researchers will use non-invasive stimulation techniques to see if they improve thinking and daily function.
Milwaukee, WisconsinAges 45 years+ - NCT06700005Recruiting
Reading study for stroke survivors and healthy adults
This study looks at how reading is affected by stroke and by normal aging. Researchers hope to learn how the brain changes after a stroke and during aging, which could help improve reading therapy for stroke survivors.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07576647Recruiting
Improving stroke research recruitment for better outcomes
This study aims to make stroke research more inclusive by improving recruitment methods. It includes people with suspected TIA or minor stroke seen in urgent clinics, as well as those hospitalized for ischemic stroke or bleeding in the brain.
Calgary, AlbertaAges Any age - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07518576Recruiting
Testing New Language and Communication Assessment Tools
This study is developing and testing new scales to measure language and communication problems after stroke. If you've had a stroke affecting speech or understanding, this research could help doctors better assess and track your recovery.
Venice, VEAges 18–90 - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT06897176RecruitingPhase 4
Cerebrolysin for speech recovery after stroke
This study tests whether a medicine called Cerebrolysin can help improve speech in people who have trouble speaking after a stroke. It is for Korean speakers who had their first stroke within the last month.
SeoulAges 19–90 - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT06946082Recruiting
Stroke study: arm and language skills in Turkish speakers
This study looks at how arm movement, body control, and mental imagery (imagining movement without actually doing it) relate to Turkish language abilities after a stroke. It aims to understand how these functions work together to help recovery.
IzmirAges 18 years+ - NCT07158216Recruiting
Long-term effects of brain stimulation in primary progressive aphasia
This study tests whether brain stimulation can help people with primary progressive aphasia (a type of dementia that mainly affects language) maintain or improve their communication skills over time. It looks at two types of stimulation: transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).
MadridAges 18 years+
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Common questions
- Are there clinical trials for aphasia?
- Yes. Clin2 currently lists 90 recruiting aphasia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aphasia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aphasia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.