Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,476 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT04743791RecruitingPhase 4
Dupilumab study for clearing mucus in moderate to severe asthma
This study tests whether dupilumab improves how well mucus is cleared from the airways in adults with moderate to severe asthma. It may help find better ways to reduce mucus-related breathing problems in people with a specific asthma type.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06461897RecruitingPhase 3
Comparing upadacitinib to dupilumab for eczema in children
This study tests whether an oral medicine (upadacitinib) works as well as a shot (dupilumab) for children aged 2 to 12 with moderate to severe eczema. It aims to see which treatment better controls symptoms like itching and skin rashes.
Little Rock, ArkansasAges 2–11 - NCT05002478Recruiting
Prone positioning for very sick babies with lung distress
This trial tests whether turning very sick, ventilated infants onto their stomach (prone positioning) can improve breathing when they have severe lung distress from likely pneumonia or bronchiolitis. It may help your baby get better oxygen levels and recover faster, while doctors closely monitor safety.
ViennaAges Up to 1 year - NCT07643766RecruitingPhase 2
Testing ENV-294 for moderate-to-severe atopic dermatitis
This study tests whether a new medication called ENV-294 can help adults with moderate-to-severe atopic dermatitis (eczema) that hasn't responded well to other treatments. The trial will check if the drug reduces itching and skin inflammation safely.
Encinitas, CaliforniaAges 18 years+ - NCT07219966RecruitingPhase 3
Study of Brenipatide for alcohol use disorder
This trial tests an injectable medicine called brenipatide to help people with moderate-to-severe alcohol use disorder reduce or stop drinking. It is for adults who are motivated to change their drinking habits.
Birmingham, AlabamaAges 18–75 - NCT06979531RecruitingPhase 2
A study of IMVT-1402 for Sjogren's disease with moderate to severe symptoms
This trial tests an experimental drug, IMVT-1402, in adults with primary Sjogren's disease who have moderate to severe symptoms. The goal is to see if it can reduce disease activity safely.
Covina, CaliforniaAges 18–74 - NCT05334940Recruiting
Care program for children and teens with multiple allergies
This trial is for people with moderate to severe allergic diseases who are about to start a biologic medicine (a targeted allergy treatment). It also looks at people who have more than one allergy condition, aiming to improve coordinated care across allergy problems.
BerlinAges 6 years+ - NCT06842199RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This trial tests an experimental drug called ICP-488 for people with moderate to severe plaque psoriasis. It aims to see if the drug can improve symptoms and is safe, and may be an option if you need stronger treatment than creams or light therapy.
Hefei, AnhuiAges 18–75 - NCT06934252RecruitingPhase 1
Study of TRB-061 for atopic dermatitis (eczema)
This trial tests an investigational drug called TRB-061 in healthy adults and people with atopic dermatitis (eczema). It aims to see if the drug is safe and how the body processes it. If you have moderate to severe eczema that started at least a year ago, you may be able to join the patient part of the study.
Belconnen, Australian Capital TerritoryAges 18–70 - NCT07132112RecruitingEarly Phase 1
GT719 injection for moderate to severe autoimmune disease
This trial tests an experimental cell therapy (GT719) for people with autoimmune diseases like lupus, inflammatory myositis, or systemic sclerosis that have not responded well to other treatments. It aims to see if this therapy can help control the disease.
Nantong, JiangsuAges 18–65 - NCT06369584Recruiting
Prone Position for Children on ECMO with Severe ARDS
This trial tests if lying face-down (prone position) helps children with severe ARDS who are already on ECMO, a machine that supports the heart and lungs. It aims to see if this position improves recovery.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT06805175Recruiting
Balance implant study for adults with dizziness
This study tests a new device that may help restore balance for people with long-term dizziness from inner ear problems. The implant is placed surgically to stimulate the balance nerve.
Antwerp, WilrijkAges 18 years+ - NCT06287970Recruiting
Testing a nerve stimulation device for chronic pelvic pain
This trial tests if a non-invasive nerve stimulation device (TaVNS) can reduce pain, urinary symptoms, and mood issues in men with moderate to severe chronic pelvic pain syndrome (CP/CPPS). It may offer a new drug-free option for symptom relief.
Beijing, Beijing MunicipalityAges 18–50 - NCT06273995Recruiting
Behavioral activation through telehealth for teens with depression
This trial tests if a telehealth program can help teenagers with depression feel better by increasing positive activities. You and a caregiver will attend weekly video sessions for 8 weeks.
Houston, TexasAges 12–18 - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT07402551RecruitingPhase 2
Testing RC1416 injection for COPD flare-ups
This trial tests an injection called RC1416 for people with moderate-to-severe COPD who still have flare-ups despite using triple inhaler therapy. It may help reduce those flare-ups and improve breathing.
Hefei, AnhuiAges 40–85 - NCT07693738RecruitingPhase 1
SSGJ-716 for healthy adults and people with atopic dermatitis
This trial tests a new medicine, SSGJ-716, in healthy adults and in people with moderate-to-severe atopic dermatitis (a type of eczema). It aims to see if the drug is safe and how the body reacts to it.
ShanghaiAges 18–45 - NCT07192146Recruiting
Patient experiences after dental emergency treatment
This study looks at how patients feel after receiving emergency dental treatment for tooth pain. It aims to understand what factors affect their recovery and satisfaction.
BangkokAges 18 years+ - NCT07558668RecruitingPhase 1
Testing SYX-5219 for atopic dermatitis in healthy people and patients
This trial tests a new drug called SYX-5219 to see if it is safe and how the body handles it. Part 1 and 2 use healthy volunteers, while Part 3 tests it in people with moderate to severe atopic dermatitis (eczema). The goal is to understand if this drug might help treat eczema symptoms like itching and skin inflammation.
Arkansas City, ArkansasAges 18–65 - NCT07311369RecruitingPhase 2
Testing a new pain tablet after abdominal surgery
This trial tests a new pain tablet (HL-1186) for people having abdominal surgery. It aims to see if the tablet is safe and works well to manage pain after the operation.
Changsha, HunanAges 18–75 - NCT07144111RecruitingPhase 1
Liver Function and Inavolisib Study
This study tests how the body processes the drug inavolisib when taken by people with moderate or severe liver problems compared to those with healthy livers. It helps doctors understand the right dose for patients with liver impairment.
Lake Forest, CaliforniaAges 18–80 - NCT06995352Enrolling by invitationPhase 4
Better pain relief after ankle surgery
This trial compares two methods of pain management after ankle surgery: a one-time injection of long-lasting numbing medicine (liposomal bupivacaine) versus a continuous nerve block via a small tube (catheter) placed near the nerve. The goal is to find which approach provides better pain relief with fewer side effects.
La Jolla, CaliforniaAges 18 years+ - NCT07474792RecruitingPhase 2
Study of ORKA-002 for moderate-to-severe plaque psoriasis
This trial tests an investigational drug called ORKA-002 for people with moderate-to-severe plaque psoriasis. It aims to see how well different doses work and if they are safe. You may qualify if your psoriasis covers at least 10% of your body or if it has not responded well enough to other treatments.
Birmingham, AlabamaAges 18–79
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,476 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.