Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 448 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06777160Recruiting
Predicting bone cement risks with AI
This study uses artificial intelligence to predict a rare but serious reaction called bone cement implantation syndrome during hip and knee replacement surgeries. It may help doctors better prepare and protect you.
ErzurumAges 18 years+ - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT04729686RecruitingPhase 4
Nerve block during hip replacement for less postoperative pain
This trial tests whether a specific nerve block given during planned hip replacement surgery can reduce pain afterward. It may help you use less opioid pain medicine, but you must meet certain safety and medication criteria.
Baltimore, MarylandAges 18–80 - NCT06384651RecruitingPhase 4
Giving antibiotic through bone vs. vein during ankle replacement
This study tests whether giving the antibiotic vancomycin through a small needle in the bone instead of a vein is safe and works well during total ankle replacement surgery. It may help you if you are having this surgery and want to prevent infection in a new way.
Houston, TexasAges 18 years+ - NCT07456787Recruiting
Cold therapy after knee replacement surgery
This trial tests a cold therapy approach (cryopressotherapy) to improve recovery after total knee replacement. It may help reduce pain and swelling so you can move better sooner.
Milan, ItalyAges 18–80 - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT07452120Recruiting
Comparing two nerve blocks for pain after hip surgery
This trial studies two different nerve block methods to see which provides better pain relief after hip replacement surgery. If you are having hip surgery and want to help find the best way to manage pain, this study may be for you.
Sivas, SivasAges 18 years+ - NCT07449403Recruiting
Pain after hip replacement: testing a nerve block
This study tests a special numbing injection (called a PENG block) given around the hip joint to see how well it controls pain after hip replacement surgery. If you are having a hip replacement under spinal anesthesia and are in generally good health, this study may help find better ways to manage your post-surgery pain.
PoznanAges 65–100 - NCT07449468Recruiting
Nerve block to prevent confusion after hip replacement
This trial tests whether a nerve block (PENG block) can reduce confusion (delirium) after hip replacement surgery in older adults. It is for people 75+ scheduled for a first-time hip replacement under spinal anesthesia.
PoznanAges 75–100 - NCT07449442Recruiting
Pain relief study after knee replacement surgery
This trial tests a special injection around the knee to improve pain control after knee replacement surgery. It may help reduce the need for strong pain medicines.
PoznanAges 65–100 - NCT07439575Recruiting
Wound closure methods in hip and knee replacement
This study compares different ways of closing the wound after hip or knee replacement surgery. It looks at which methods heal best with fewer problems.
Istanbul, IstanbulAges 30 years+ - NCT07442721Recruiting
Comparing two types of nerve blocks for hip replacement pain
This study compares two different nerve block methods to see which provides better pain relief for people having a partial hip replacement. It will help doctors choose the best way to manage pain after surgery.
El Fayoum Qesm, Faiyum GovernorateAges 50–90 - NCT06040827Recruiting
Study of a knee implant extension for knee replacement
This trial is for adults having their first knee replacement surgery. It tests a special part (tibial extension) of a common knee implant system. Researchers will follow participants over time to see how well it works.
Fayetteville, ArkansasAges 18 years+ - NCT07432009Recruiting
Hip replacement and confusion risk in older adults
This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.
BrnoAges 65 years+ - NCT07429955Recruiting
Study on muscle and recovery after hip surgery in older adults
This trial looks at how muscle health affects your ability to get back to normal activities after hip replacement surgery for a broken hip or severe arthritis. By using MRI scans and other tests, researchers hope to understand if having less muscle makes recovery harder.
MontpellierAges 75 years+ - NCT07430228Enrolling by invitationPhase 2
Can oxytocin help you recover faster after hip replacement?
This study tests if a medicine called oxytocin, given through a vein during surgery, can help people recover more quickly after a total hip replacement. It is for adults in generally good health who are scheduled for a first-time hip replacement.
Winston-Salem, North CarolinaAges 18–75 - NCT06701474Recruiting
Knee replacement recovery: comparing body composition groups
This study looks at how well people recover after total knee replacement, comparing those with different body composition levels. The goal is to see if a measure called 'phase angle' affects recovery of strength and function.
Yongin-si, Gyeonggi-doAges 55 years+ - NCT05412615Recruiting
Meniscal graft surgery for wrist arthritis
This trial studies whether using a donor meniscus (meniscal allograft) during wrist replacement surgery can help people with painful wrist osteoarthritis. It’s mainly for certain types of arthritis changes in the wrist (SLAC or SNAC) and specific age ranges.
Englewood, ColoradoAges 30–80 - NCT07378215RecruitingPhase 4
Steroids for better recovery after hip replacement
This study tests whether a single dose of steroids (dexamethasone) given during hip replacement surgery can improve your recovery and quality of life. It may help reduce pain and swelling after the procedure.
Genk, LimburgAges 60 years+ - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT07371390Recruiting
Minimal sedation for knee replacement surgery
This trial tests whether less sedation during knee replacement surgery can improve recovery. It may help you if you are having your first total knee replacement and can have spinal anesthesia.
Rochester, MinnesotaAges 18 years+ - NCT07367789Recruiting
Predicting recovery after knee replacement using smart insoles
This study uses special insoles to measure how you walk before and after a knee replacement. The goal is to see if these measurements can help predict how well you will recover after surgery.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT07354542Recruiting
Relaxation therapy for pain and sleep after joint replacement
This trial tests if different relaxation methods, such as breathing exercises or virtual reality, can help reduce pain and improve sleep after hip or knee replacement surgery. It is designed for people who have had a joint replacement and are able to use a mobile phone or tablet.
Bartın, CenterAges 18 years+
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 448 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.