Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06780319Recruiting
Digital rehab after hip replacement surgery
This trial compares a digital (app-based) rehabilitation program with standard care after hip replacement surgery. If you have a smartphone and speak French, this study could help you recover from home.
MérignacAges 18–80 - NCT06740214RecruitingPhase 3
Different doses of liposomal bupivacaine for knee replacement pain
This trial tests different doses of a long-acting painkiller (liposomal bupivacaine) injected into a nerve block in the thigh to see which dose works best for pain after knee replacement surgery. It may help you have better pain control and recover faster.
Hong Kong, Hong KongAges 18–80 - NCT06733480Recruiting
Band Connect for physical therapy after shoulder surgery
This study tests a new physical therapy tool called Band Connect, which may help people follow their rehab exercises better after shoulder surgery. Researchers want to see if it improves satisfaction and recovery outcomes.
Cleveland, OhioAges 18–89 - NCT06729294Recruiting
Does music help during knee replacement surgery?
This study tests if listening to music during knee replacement surgery under spinal anesthesia can lower anxiety, pain, and stress hormone levels. It may help make the experience calmer for patients.
Kocasinan, KayseriAges 18 years+ - NCT06342843Recruiting
Comparing two ways to do hip replacement surgery
This trial compares two different surgical approaches for total hip replacement: the direct superior approach and the posterolateral approach. It aims to see which one leads to better recovery and outcomes for people with severe hip arthritis.
Breda, North BrabantAges 18–99 - NCT06687109Recruiting
Joint replacement surgery registry study
This study collects information from people having joint replacement surgery to track how they do over time and improve care.
Spokane, WashingtonAges 18 years+ - NCT06634654Recruiting
AI-guided knee replacement study
This trial tests whether using artificial intelligence can improve recovery from total knee replacement by tailoring care to your body's needs. It may help people with severe knee arthritis who have not had major knee surgery before.
Rome, ItalyAges 18 years+ - NCT06580899Enrolling by invitationPhase 4
Knee pain pump study for single knee replacement surgery
This study tests whether a small pain pump placed in your knee joint during surgery can help control pain after a single knee replacement. It is for people who are having outpatient knee replacement surgery and have not been taking strong pain medicines recently.
Charlotte, North CarolinaAges 18 years+ - NCT06565377Recruiting
Pre-surgery program for knee replacement patients
This trial tests a program of exercise, education, and support to help you prepare for knee replacement surgery. It aims to improve your recovery and quality of life.
Geel, AntwerpenAges 18 years+ - NCT06287021Recruiting
Bone healing after hip replacement with two types of titanium cups
This trial compares how bone grows around two different titanium cups used in hip replacement surgery. It aims to see which cup design leads to better bone remodeling and stability after the procedure.
MilanAges 40–85 - NCT06447922Enrolling by invitation
Metal Levels After Knee Replacement
This study measures metal levels in the blood after knee replacement surgery. It may help researchers understand how metal from the new joint affects the body.
Rochester, MinnesotaAges 18–100 - NCT06293352Recruiting
Comparing two antibiotic spacers for knee infection
This trial compares two types of antibiotic spacers for people with a long-term knee replacement infection. It tests whether a spacer made entirely of antibiotic cement or one with a metal core works better to treat the infection before a new knee replacement.
Chicago, IllinoisAges 18 years+ - NCT06133933Enrolling by invitation
Shoulder replacement and pain medication study
This study looks at how your pain tolerance before a total shoulder replacement might relate to how much pain medication you need after surgery. The goal is to help doctors better manage pain medication after surgery.
Camden, New JerseyAges 18 years+ - NCT05845021Recruiting
Screening and referral for bone health after hip or knee surgery
This study looks at a simple plan for surgeons to identify people with low bone strength (osteoporosis) and refer them for bone health care after hip or knee replacement surgery. It may help you get evaluated and treated earlier if you have osteoporosis.
Columbia, MarylandAges 50 years+ - NCT06083480RecruitingPhase 4
Reducing stress to prevent long-term pain after knee replacement
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
Nashville, TennesseeAges 50 years+ - NCT05993845Recruiting
Hip replacement surgery study
This study looks at how doctors plan and perform hip replacement surgery using a special front approach. It may help improve how the surgery is done.
Baden, Canton of AargauAges 18 years+ - NCT05876143Recruiting
Study of a knee implant with patient follow-up surveys
This trial follows people who already have (or are receiving) a specific partial knee implant to see how they do over time using questionnaires after surgery. It may help improve care for future patients with knee arthritis who get this type of implant.
Pierre-BéniteAges 18 years+ - NCT05789784Enrolling by invitation
Using a shoulder-mobility app after shoulder replacement
This trial tests whether the Zimmer Biomet mymobility smartphone app improves outcomes after a reverse total shoulder replacement. It may help by supporting follow-up exercises and tracking progress after surgery.
Palm Beach Gardens, FloridaAges 18 years+ - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT05288803Recruiting
Personalized rehab after knee replacement for veterans
This study tests a personalized rehabilitation program for veterans who have had a total knee replacement. It aims to improve recovery by tailoring therapy to each person's progress.
Aurora, ColoradoAges 40–90 - NCT05290818Recruiting
Robotic vs standard knee replacement for inner-joint wear
This trial compares robotic-assisted knee replacement with the usual (non-robotic) approach for people with severe arthritis on the inner (medial) side of the knee. It aims to see which method works better for pain and function while matching the right knee anatomy for certain implant types.
Edinburgh, LothianAges 50–75 - NCT05097976RecruitingPhase 4
Medrol tablets to reduce pain after knee replacement
This trial tests whether a short course of Medrol (methylprednisolone) can improve recovery after outpatient total knee replacement done for osteoarthritis. You would be randomly assigned to receive Medrol or a comparison treatment.
Oak Brook, IllinoisAges 18 years+ - NCT04868305Recruiting
Compare two surgery types for unstable hip fractures
This trial compares an intramedullary nail versus a hip replacement for unstable hip fractures. It may help guide which operation works best to restore walking and function after injury.
StavangerAges 65–120 - NCT04848896Recruiting
Safety and outcomes study of a smart knee replacement
This trial studies whether a “smart” knee replacement system (CORI) is safe and works well for people getting a total knee arthroplasty (TKA). If you’re a good candidate for a cemented standard knee replacement, the study follows you for two years to check results after surgery.
EppingAges 18 years+
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 450 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.