Clinical trials
Atherosclerotic Disease clinical trials
Below are recruiting atherosclerotic disease clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06875973RecruitingPhase 3
Pelacarsen long-term extension study
This trial is for people who have already finished taking pelacarsen in a previous study. It offers continued access to the drug and checks long-term safety.
Birmingham, AlabamaAges 18–100 - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT06962488Recruiting
Personalized blood pressure care using genetic risk
This study uses your genetic information (a polygenic risk score) to guide personalized blood pressure management. It aims to help people with high blood pressure and overall poor heart health improve their levels through tailored advice.
Birmingham, AlabamaAges 18–55 - NCT07034690RecruitingPhase 4
Better cholesterol control for high-risk patients
This study tests whether an educational program can help people with high cholesterol and heart disease get their LDL cholesterol levels lower. It involves watching online videos and working with your doctor to adjust treatments.
Abu DhabiAges 18–100 - NCT07334834Recruiting
Better cholesterol management for people with artery disease
This study tests a team-based approach to help people with artery disease (like heart attacks or leg blockages) get their cholesterol to a healthier level. If your LDL is above 70, you may benefit from extra support to manage your medications.
Aurora, ColoradoAges 18 years+ - NCT06813339RecruitingEarly Phase 1
Testing a new drug in healthy people and those with heart condition
This trial tests a new medicine called UDP-003 in two groups: healthy volunteers and people who had a heart event (acute coronary syndrome) at least a year ago. The goal is to see if the drug is safe and how the body handles it, which could lead to better treatments for heart disease.
Adelaide, South AustraliaAges 18–79 - NCT07487363RecruitingPhase 1/Phase 2
TB-500 for heart health in stable artery disease
This study tests if TB-500 can improve blood markers of cardiovascular health in people with stable artery disease. It is an early-phase trial to see if the drug is safe and shows promise.
Shenzhen, GuangdongAges 40–75 - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT06025305Enrolling by invitation
Using AI to find dangerous heart plaque on CT scans
This study uses artificial intelligence to look at CT scans of the heart to find which fatty deposits (plaque) in the arteries might be dangerous. It may help doctors better predict heart attacks.
Nanjing, JiangsuAges 18 years+ - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+ - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT06313645Recruiting
Blood vessel aging and heart attack risk study
This study looks at how blood vessel aging relates to the type of fatty buildup in your arteries that can cause heart attacks. If you've had a recent heart attack, chest pain (angina), or minor artery disease and do not have advanced heart failure, kidney failure, active cancer, or prior bypass surgery, you may be able to join.
Milan, LombardyAges 18–75 - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT07352852Recruiting
Rapamycin-coated stent for narrowed brain arteries
This study tests a special stent that slowly releases a drug (rapamycin) to keep a narrowed brain artery open. It is for patients who have had strokes despite medical treatment.
Qingdao, ShandongAges 18–80 - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT07254572RecruitingPhase 4
Comparing diabetes drugs for heart health in prediabetes
This trial tests whether certain diabetes medications can help prevent worsening of heart disease in people who have prediabetes (higher than normal blood sugar, but not yet diabetes). It may be a good fit if you have known coronary artery disease and prediabetes.
WarsawAges 18–80 - NCT06734221Recruiting
Testing a paclitaxel-coated balloon for leg artery disease
This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.
Chrzanów, MalopolskaAges 18 years+
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Common questions
- Are there clinical trials for atherosclerotic disease?
- Yes. Clin2 currently lists 68 recruiting atherosclerotic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerotic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerotic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Atherosclerotic Cardiovascular Disease
- Atherosclerotic Cardiovascular Disease (ASCVD)
- Atherosclerotic Plaque
- Renal Artery Stenosis Atherosclerotic
- Intracranial Atherosclerotic Stenosis
- ICAD - Intracranial Atherosclerotic Disease
- Intracranial Atherosclerotic Stenosis (ICAS)
- Symptomatic Intracranial Atherosclerotic Stenosis
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.