Clinical trials
Bladder Cancer clinical trials
Below are recruiting bladder cancer clinical trials, each written for real people, not researchers. We’re tracking 374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06040762Recruiting
Get moving before bladder cancer surgery
This study tests whether a home-based exercise program before surgery can help improve physical function in people with bladder or upper tract urothelial cancer. If you are planning to have surgery to remove your bladder or upper urinary tract, you may be able to join.
Seattle, WashingtonAges 18 years+ - NCT06242470RecruitingPhase 1
Study of MGC026 for advanced solid tumors
This trial tests a new drug called MGC026 that targets a protein called B7-H3 on cancer cells, aiming to shrink or slow different advanced solid tumors. It is an early-phase study to find the right dose and check safety.
Los Angeles, CaliforniaAges 18 years+ - NCT06337942Recruiting
Bladder or kidney-bladder transplant from a deceased donor
This trial offers a first-in-human transplant of a bladder or a kidney combined with a bladder from a deceased donor. It is for people with severe bladder problems or bladder cancer who already need a new bladder or are on immune-suppressing medicines for a prior organ transplant.
Los Angeles, CaliforniaAges 18–70 - NCT02609269Enrolling by invitation
Study using your Decipher genetic test results
This study uses the Decipher genetic test results you already had to help researchers learn how to improve cancer care. You may be included simply because you previously completed that specific test.
Ages Any age - NCT05962541RecruitingPhase 4
Using bladder scans to plan repeat surgery for bladder cancer
This trial checks whether a bladder scan and score (VI-RADS from MRI) can help doctors choose the right way to do a second look surgery for non-muscle-invasive bladder cancer. The goal is to reduce the chance of needing extra (“secondary”) resections while still catching important disease early.
Rome, LazioAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT02379429Recruiting
Collecting bladder/urothelial cancer tissue for future research
This study looks at urothelial cancer (often bladder cancer) samples taken during diagnosis or standard treatment. It may help researchers better understand the disease by using tissue that doctors already need to collect for care.
Bethesda, MarylandAges 18–120 - NCT06101277Recruiting
Local therapy for limited new cancer growth in digestive cancers
This trial tests a cancer treatment that uses local therapies (like radiation or targeted heat) to destroy a small number of growing spots. It is for people with certain gastrointestinal cancers whose main treatment is working well except for a few new spots, so they can avoid switching to a different drug right away.
Sacramento, CaliforniaAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT07327489Recruiting
Live tumor biopsy study to predict immunotherapy response
This trial studies how well immunotherapy might work by analyzing fresh tumor biopsies. It may help predict which treatments are best for your cancer.
Fort Smith, ArkansasAges 18 years+ - NCT07087860RecruitingPhase 2
Plasma exchange plus targeted therapy for advanced bladder cancer
This trial tests a procedure called therapeutic plasma exchange (TPE) combined with the drugs enfortumab vedotin and pembrolizumab for people with advanced bladder cancer that has stopped responding to standard treatments. The goal is to see if TPE helps the drugs work better.
Rochester, MinnesotaAges 18 years+ - NCT07038928Recruiting
Treatment patterns and markers in bladder cancer in Russia
This study looks at how bladder cancer is treated and what biological markers are present in patients in Russia. If you join, you may help doctors learn more about which treatments work best based on your tumor type.
ArkhangelskAges 18 years+ - NCT07750470Recruiting
Pet scan to guide treatment for muscle-invasive bladder cancer
This study uses a special PET/CT scan to see how far your bladder cancer has spread. The results may help doctors plan the best treatment for you.
FerraraAges 18 years+ - NCT05792033Recruiting
Registry for early T1 bladder cancer after repeat bladder surgery
This study follows people with newly diagnosed early bladder cancer (T1) to better understand outcomes and guide follow-up care. You may be able to join if your cancer is confirmed after a second look bladder procedure and scans show no spread.
ViennaAges 18–90 - NCT06679920Recruiting
New imaging probe to improve bladder cancer diagnosis
This trial tests a new optical probe that gives doctors a clearer view of bladder tumors during cystoscopy. It may help make diagnosis and treatment more accurate.
Amsterdam, North HollandAges 18 years+ - NCT06972771Recruiting
Trop2-imaging dye helps find early bladder cancer during surgery
This study uses a special imaging dye that targets a protein called Trop2, which is often found on bladder cancer cells. During your surgery, the dye will help doctors see the cancer more clearly with advanced imaging so they can remove it completely.
Kunming, YunnanAges 18–80 - NCT07019220RecruitingPhase 2
Chemoablation for low-risk bladder cancer
This trial tests using chemotherapy directly into the bladder to treat low-grade bladder cancer that has come back, as an alternative to surgery. It may help people with small, low-grade tumors avoid the need for a more invasive procedure.
ViennaAges 18 years+ - NCT07080333Recruiting
Bladder cancer and the gut microbiome study
This study looks at the bacteria in your gut and bladder to understand how they may relate to bladder cancer. It is for men who are having their first tumor removal for suspected bladder cancer, and helps researchers learn if the microbiome plays a role.
CannesAges 18 years+ - NCT05000294RecruitingPhase 1/Phase 2
Atezolizumab plus tivozanib for hard-to-treat “cold” cancers
This early-stage study tests whether combining atezolizumab and tivozanib can shrink advanced, hard-to-treat cancers that do not strongly activate the immune system (“immunologically cold”). It is for people whose cancer has already been treated or has no good standard options.
Gainesville, FloridaAges 18–99 - NCT04585750RecruitingPhase 1/Phase 2
Study drug for TP53 Y220C-mutated advanced cancers
This early-phase study tests PC14586 (rezatapopt) in people with advanced or metastatic solid cancers that carry a specific TP53 mutation called Y220C. It mainly looks at safety and how well the treatment may work, sometimes combined with pembrolizumab.
Irvine, CaliforniaAges 12 years+ - NCT07646145RecruitingPhase 2
Disitamab Vedotin Plus Mitomycin C for HER2-Positive Bladder Cancer
This trial tests a combination of two medications—disitamab vedotin (a targeted therapy) and mitomycin C (a chemotherapy)—for people with early-stage bladder cancer that has a specific protein called HER2. The goal is to prevent cancer from coming back after surgery in people who cannot or will not receive BCG treatment.
Taiyuan, ShanxiAges 18 years+ - NCT07324798Recruiting
Adaptive Radiation Therapy for Genitourinary Cancers
This trial tests a more precise form of radiation therapy (adaptive radiotherapy) for people with urological cancers. It aims to adjust the radiation beam in real time to better target the tumor and protect healthy tissues, which may lead to fewer side effects.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07073703Recruiting
A personalized program for frailty in bladder or kidney cancer patients
This trial tests a personalized 6-month program to reduce frailty in older patients who are about to have surgery for bladder or kidney cancer. The program includes exercise and support, and aims to help patients stay stronger during and after treatment.
Saint-EtienneAges 65 years+ - NCT06781879RecruitingPhase 4
Comparing bladder medication vs surgery for returning low-grade bladder cancer
This trial tests whether a chemotherapy drug placed directly into the bladder (chemoablation) works as well as surgery followed by chemotherapy for people whose low-grade bladder tumors have come back. It aims to find a less invasive option that still controls the cancer.
AalborgAges 18 years+
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Common questions
- Are there clinical trials for bladder cancer?
- Yes. Clin2 currently lists 374 recruiting bladder cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bladder cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bladder cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.