Clinical trials
Bladder Cancer clinical trials
Below are recruiting bladder cancer clinical trials, each written for real people, not researchers. We’re tracking 373 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06916494RecruitingPhase 1
Rutin plus immunotherapy and chemo before bladder cancer surgery
This trial tests a combination of the natural supplement rutin, an immunotherapy (tislelizumab), and two chemotherapy drugs (gemcitabine and cisplatin) before surgery for bladder cancer that didn't respond to initial chemo. It aims to see if this mix can shrink tumors better.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06242470RecruitingPhase 1
Study of MGC026 for advanced solid tumors
This trial tests a new drug called MGC026 that targets a protein called B7-H3 on cancer cells, aiming to shrink or slow different advanced solid tumors. It is an early-phase study to find the right dose and check safety.
Los Angeles, CaliforniaAges 18 years+ - NCT06040762Recruiting
Get moving before bladder cancer surgery
This study tests whether a home-based exercise program before surgery can help improve physical function in people with bladder or upper tract urothelial cancer. If you are planning to have surgery to remove your bladder or upper urinary tract, you may be able to join.
Seattle, WashingtonAges 18 years+ - NCT05646485Recruiting
Bladder cancer screening for people at higher risk
This trial tests screening for bladder cancer in people who have higher risk due to age, smoking, and certain job exposures. It may help find bladder cancer earlier when treatment can be more effective.
Dallas, TexasAges 50 years+ - NCT04861584RecruitingPhase 2
Immunotherapy plus chemo before bladder surgery for advanced cancer
This trial studies giving toripalimab (an immunotherapy) together with gemcitabine and cisplatin before bladder surgery. It aims to shrink locally advanced bladder cancer and make surgery more effective by using the immune system and chemotherapy together.
Guangzhou, GuangdongAges 18–75 - NCT04574960RecruitingPhase 3
Neoadjuvant chemotherapy before kidney/ureter cancer surgery
This Phase 3 trial studies giving cisplatin-based chemotherapy before surgery for certain newly diagnosed upper-urinary-tract urothelial cancers (kidney/ureter). It may help shrink the cancer and improve outcomes by treating microscopic disease earlier.
Ottawa, OntarioAges 18 years+ - NCT02609269Enrolling by invitation
Study using your Decipher genetic test results
This study uses the Decipher genetic test results you already had to help researchers learn how to improve cancer care. You may be included simply because you previously completed that specific test.
Ages Any age - NCT05962541RecruitingPhase 4
Using bladder scans to plan repeat surgery for bladder cancer
This trial checks whether a bladder scan and score (VI-RADS from MRI) can help doctors choose the right way to do a second look surgery for non-muscle-invasive bladder cancer. The goal is to reduce the chance of needing extra (“secondary”) resections while still catching important disease early.
Rome, LazioAges 18 years+ - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT02379429Recruiting
Collecting bladder/urothelial cancer tissue for future research
This study looks at urothelial cancer (often bladder cancer) samples taken during diagnosis or standard treatment. It may help researchers better understand the disease by using tissue that doctors already need to collect for care.
Bethesda, MarylandAges 18–120 - NCT06101277Recruiting
Local therapy for limited new cancer growth in digestive cancers
This trial tests a cancer treatment that uses local therapies (like radiation or targeted heat) to destroy a small number of growing spots. It is for people with certain gastrointestinal cancers whose main treatment is working well except for a few new spots, so they can avoid switching to a different drug right away.
Sacramento, CaliforniaAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT07327489Recruiting
Live tumor biopsy study to predict immunotherapy response
This trial studies how well immunotherapy might work by analyzing fresh tumor biopsies. It may help predict which treatments are best for your cancer.
Fort Smith, ArkansasAges 18 years+ - NCT07087860RecruitingPhase 2
Plasma exchange plus targeted therapy for advanced bladder cancer
This trial tests a procedure called therapeutic plasma exchange (TPE) combined with the drugs enfortumab vedotin and pembrolizumab for people with advanced bladder cancer that has stopped responding to standard treatments. The goal is to see if TPE helps the drugs work better.
Rochester, MinnesotaAges 18 years+ - NCT05792033Recruiting
Registry for early T1 bladder cancer after repeat bladder surgery
This study follows people with newly diagnosed early bladder cancer (T1) to better understand outcomes and guide follow-up care. You may be able to join if your cancer is confirmed after a second look bladder procedure and scans show no spread.
ViennaAges 18–90 - NCT07750470Recruiting
Pet scan to guide treatment for muscle-invasive bladder cancer
This study uses a special PET/CT scan to see how far your bladder cancer has spread. The results may help doctors plan the best treatment for you.
FerraraAges 18 years+ - NCT06679920Recruiting
New imaging probe to improve bladder cancer diagnosis
This trial tests a new optical probe that gives doctors a clearer view of bladder tumors during cystoscopy. It may help make diagnosis and treatment more accurate.
Amsterdam, North HollandAges 18 years+ - NCT07080333Recruiting
Bladder cancer and the gut microbiome study
This study looks at the bacteria in your gut and bladder to understand how they may relate to bladder cancer. It is for men who are having their first tumor removal for suspected bladder cancer, and helps researchers learn if the microbiome plays a role.
CannesAges 18 years+ - NCT07038928Recruiting
Treatment patterns and markers in bladder cancer in Russia
This study looks at how bladder cancer is treated and what biological markers are present in patients in Russia. If you join, you may help doctors learn more about which treatments work best based on your tumor type.
ArkhangelskAges 18 years+ - NCT07019220RecruitingPhase 2
Chemoablation for low-risk bladder cancer
This trial tests using chemotherapy directly into the bladder to treat low-grade bladder cancer that has come back, as an alternative to surgery. It may help people with small, low-grade tumors avoid the need for a more invasive procedure.
ViennaAges 18 years+ - NCT05000294RecruitingPhase 1/Phase 2
Atezolizumab plus tivozanib for hard-to-treat “cold” cancers
This early-stage study tests whether combining atezolizumab and tivozanib can shrink advanced, hard-to-treat cancers that do not strongly activate the immune system (“immunologically cold”). It is for people whose cancer has already been treated or has no good standard options.
Gainesville, FloridaAges 18–99 - NCT04585750RecruitingPhase 1/Phase 2
Studying a new drug for cancers with a specific TP53 change
This trial tests a new drug (rezatapopt) for people with advanced cancers that have a specific change in the TP53 gene, called Y220C. The drug is designed to target this change and may slow or stop cancer growth. Some participants may also receive an immunotherapy drug called pembrolizumab (Keytruda).
Irvine, CaliforniaAges 12 years+ - NCT07646145RecruitingPhase 2
Disitamab Vedotin Plus Mitomycin C for HER2-Positive Bladder Cancer
This trial tests a combination of two medications—disitamab vedotin (a targeted therapy) and mitomycin C (a chemotherapy)—for people with early-stage bladder cancer that has a specific protein called HER2. The goal is to prevent cancer from coming back after surgery in people who cannot or will not receive BCG treatment.
Taiyuan, ShanxiAges 18 years+ - NCT07324798Recruiting
Adaptive Radiation Therapy for Genitourinary Cancers
This trial tests a more precise form of radiation therapy (adaptive radiotherapy) for people with urological cancers. It aims to adjust the radiation beam in real time to better target the tumor and protect healthy tissues, which may lead to fewer side effects.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for bladder cancer?
- Yes. Clin2 currently lists 373 recruiting bladder cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bladder cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bladder cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.