Clinical trials
Bone Loss clinical trials
Below are recruiting bone loss clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04112992Recruiting
Registry for post-injury long bone bone defects
This study is a registry that collects real-world information about adults with bone gaps in the long bones caused by injury. It may help researchers understand what treatments work best and improve care for these defects over time.
Los Angeles, CaliforniaAges 18 years+ - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT05764733RecruitingPhase 4
How bone exercise, alendronate, and diet affect bone strength
This trial studies whether doing a structured bone-focused exercise program, taking alendronate (a medication that slows bone loss), and making a calorie-reducing diet can improve bone strength in people with low bone density. It also compares different combinations to see what helps most and is safest for you.
Aurora, ColoradoAges 60 years+ - NCT07526129Recruiting
Ridge Preservation After Back Tooth Extraction
This study looks at whether a procedure called ridge preservation, done after removing upper back teeth, helps prevent the need for sinus bone grafting later. Researchers will compare patients who had this procedure with those who didn't, using 10 years of X-ray records.
Beirut, BeirutAges 18 years+ - NCT06830187Recruiting
Bone density, vitamin D, and hearing loss in otosclerosis
This study looks at how bone density and vitamin D levels relate to hearing loss in people with otosclerosis, a condition where extra bone growth in the ear causes hearing problems. It may help doctors understand why some people lose more hearing than others.
AnkaraAges 18 years+ - NCT07419269Recruiting
Comparing donor vs. patient bone grafts for jawbone repair
This trial tests whether donated (allogenic) bone blocks work as well as your own bone to rebuild the jaw so dental implants can be placed. It's for people missing 1-4 teeth where the bone ridge is too thin.
Graz, StyriaAges 18 years+ - NCT07669792Recruiting
Bone shell vs fabric for narrow lower jawbone
This study compares two ways to rebuild a narrow lower jawbone so you can get dental implants. One method uses a special bone shell technique, and the other uses a strong fabric material. Your doctor will check if your jawbone is wide enough and healthy for this surgery.
CairoAges 18–65 - NCT04449211RecruitingEarly Phase 1
3D-printed implant for large bone defects
This trial studies whether a custom 3D-printed implant helps heal a large bone defect after injury or tumor removal. If you have a bone gap bigger than 5 centimeters and can safely have surgery, this may be a treatment option being tested.
Ho Chi Minh CityAges 18 years+ - NCT05005039Recruiting
Study how bariatric surgery may affect bone strength
This trial studies whether bariatric surgery (bypass or sleeve) changes bone loss in postmenopausal women with obesity. It may help doctors understand who is at higher risk for weaker bones and how to prevent it.
LilleAges 45–70 - NCT06221306Recruiting
Comparing narrow vs standard dental implants for jaw bone loss
This trial tests whether narrow dental implants can preserve jaw bone better than standard implants with bone grafting in people missing back teeth. If you have a narrow jawbone, this study may help determine which option works best for you.
Cairo, Greater CairoAges 18 years+ - NCT06559605Recruiting
Comparing 3D Zirconia Barrier vs Titanium Mesh for Bone Growth
This study tests a new 3D-printed zirconia barrier to see if it helps grow bone better than a standard titanium mesh. It may be an option if you need more jawbone for dental implants.
CairoAges 20–70 - NCT02469662Recruiting
Study of outcomes after Nexel total elbow replacement
This study looks at how well the Nexel total elbow replacement works over time for people who need an elbow replacement due to pain, damage, or instability. It may help the doctors understand which patients benefit most and what results to expect.
Golden, ColoradoAges 18 years+ - NCT07509281Recruiting
How implant parts affect healing and gum health
This trial compares different shapes and heights of the abutment (the connector piece between the implant and crown) to see how they affect gum and bone healing. It is for people who need a single or few back teeth replaced with a dental implant.
Valencia, ValenciaAges 18 years+ - NCT04713774Recruiting
Tracking bone and blood vessel changes after kidney transplant
This study follows people who recently received a kidney transplant to see how bone strength and blood-vessel calcifications change over time. It may help doctors better understand what to monitor after transplant and how best to protect bone and heart health.
LiègeAges 18 years+ - NCT07254117Recruiting
Study on gum tissue healing for severe gum disease
This trial tests whether special granulation tissue can help regenerate bone and gum support in people with severe gum disease who still have deep bone pockets after initial treatment. It may offer a better way to heal these defects.
RigaAges Any age - NCT07389681Recruiting
Bone loss repair: Masquelet technique vs transport nails
This study compares two surgical techniques for rebuilding bone in the lower leg or thigh after significant bone loss. If you need this type of surgery, you may be able to join and help doctors learn which method works best.
BordeauxAges 18 years+ - NCT07253493Recruiting
Bone loss and nerve activity study for postmenopausal women
This study looks at how bone loss in the hip might affect nerve signals to muscles. It compares postmenopausal women with weak bones (osteoporosis in the hip) to those with normal bone density.
Bahçelievler, IstanbulAges 18–65 - NCT06533397Recruiting
Testing a new bone graft for sinus lifts
This study tests a new bone graft material for sinus lifts, a procedure to add bone in the upper jaw so dental implants can be placed. It may help people who are missing bone in the back of their upper jaw due to enlarged sinuses.
Budapest, BudapestAges 18 years+ - NCT07483086Recruiting
Implant position for thin gum patients
This study tests whether the vertical position of a dental implant affects bone loss around it, specifically for people with thin gums. If you are missing a single upper front tooth or premolar, you may be a candidate.
CairoAges 18 years+ - NCT06798116Enrolling by invitation
Gum disease treatment with platelet-rich fibrin and albumin gel
This study tests a new treatment for severe gum disease. It combines a natural blood product (platelet-rich fibrin) with a special albumin gel to help repair bone defects around teeth. The goal is to see if this mixture helps the bone grow back better than standard treatment.
Al MansurahAges 25–55 - NCT07044310RecruitingPhase 2
Probiotics for preventing bone loss during breast cancer hormone therapy
This trial tests if a probiotic supplement can help prevent bone loss in women with HR-positive breast cancer who are starting an aromatase inhibitor. You would take the probiotic daily and provide blood and stool samples to see how it affects your bone health.
Jacksonville, FloridaAges 18 years+ - NCT07433322Recruiting
Preserving gum and bone after back tooth removal
This study tests a procedure to preserve the bone and gum after removing upper back teeth, which may help prepare the area for future dental implants.
Richmond, VirginiaAges 18 years+ - NCT06457373Recruiting
Donated vs. your own tooth graft for bone preservation
This trial tests whether a special bone graft made from donated teeth works as well as a graft made from your own teeth to preserve the bone after wisdom tooth removal. It may help you keep more bone in your jaw for future dental work.
Damietta, New-DamiettaAges 25–35 - NCT07488039Recruiting
Labral repair for shoulder instability with minor bone loss
This trial tests a surgery to repair a torn shoulder socket rim (labrum) in people with recurrent shoulder dislocations and minor bone loss. It aims to restore shoulder stability and prevent future dislocations.
Cairo, Cairo GovernorateAges 16 years+
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Common questions
- Are there clinical trials for bone loss?
- Yes. Clin2 currently lists 97 recruiting bone loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.