Clinical trials
Bone Loss clinical trials
Below are recruiting bone loss clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07093853Recruiting
Comparing two ways to attach a lower denture to four implants
This trial tests two ways to attach a lower denture to four dental implants: using four small clips (locators) or a single bar that connects all four implants. The goal is to find which method is more stable and comfortable for people who are completely toothless in the lower jaw.
Al Mansurah, MenoufiaAges 40–70 - NCT07090694Enrolling by invitationPhase 1
Sinus lift with or without platelet-rich fibrin for dental implants
This trial compares two ways to place dental implants in the upper jaw where there is not enough bone: one uses a special clotting substance (PRF) and the other does not. The goal is to see which method works better.
RiyadhAges 25–65 - NCT07083531Recruiting
Bone health study for older Black women with sickle cell trait
This study looks at how carrying the sickle cell trait (not the disease) affects bone density, physical function, and frailty in older African American women. It aims to help understand bone loss risk and prevent fractures.
Farmington, ConnecticutAges 50 years+ - NCT04246944Recruiting
Induced membrane bone repair study in critical defects
This study looks at how a specific bone-repair technique (called induced membrane reconstruction) works in people with large “critical-sized” bone defects. It may help doctors understand the results and properties of this method in both children and adults.
AmiensAges 9 months–60 years - NCT06930781Recruiting
Study of Ponto implants outside of the operating room
This study looks at how well Ponto implants work when placed in a clinic or office setting instead of a hospital operating room. It is for adults who already had this procedure in 2019 or later.
Sacramento, CaliforniaAges 18 years+ - NCT06527664Recruiting
Custom hip implant for failed arthritis treatments
This trial tests a custom-made hip socket implant for people who have had a failed hip replacement or arthritis treatment. It aims to see if a personalized implant can provide a better solution.
BolognaAges 18 years+ - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT06457373Recruiting
Donated vs. your own tooth graft for bone preservation
This trial tests whether a special bone graft made from donated teeth works as well as a graft made from your own teeth to preserve the bone after wisdom tooth removal. It may help you keep more bone in your jaw for future dental work.
Damietta, New-DamiettaAges 25–35 - NCT05533528Recruiting
Save gum tissue in surgery for severe periodontitis
This trial studies a way to preserve gum (periodontal) “granulation” tissue during surgical treatment for severe periodontitis (gum disease). It may help patients heal better after surgery, especially when deep gum pockets do not improve after non-surgical care.
MurciaAges 18 years+ - NCT04954664Recruiting
Bone graft particles to help dental implants fit in missing teeth areas
This study tests a bone-grafting approach (using processed donor bone particles, with or without a growth factor) to help dental implants work when the jaw bone is too narrow. It may help people get implants placed more safely and effectively in areas with missing teeth.
Birmingham, AlabamaAges 18–99 - NCT04809064Recruiting
Compare open vs arthroscopic surgery for unstable shoulder with bone loss
This trial compares two surgery approaches for people with a traumatic, unstable (dislocating) shoulder when they also have moderate bone loss. It may help identify which method restores stability better and with fewer problems for the right patients.
Tempe, ArizonaAges 17–50 - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT06762730RecruitingPhase 4
Zoledronic acid to prevent bone loss from HIV treatment
This trial tests if zoledronic acid, a drug that strengthens bones, can prevent bone loss caused by starting HIV treatment. It is for people newly diagnosed with HIV who have not yet taken any HIV medication.
HaifaAges 18 years+ - NCT06077513Enrolling by invitation
Comparing two mesh frames for jawbone grafting
This trial tests two different metal mesh frames used to rebuild bone in the jaw before placing a dental implant. If you need a bone graft for a missing tooth, this study may help find the best option for you.
Boston, MassachusettsAges 18–80 - NCT07633665Recruiting
Safety and effectiveness study of dental implants
This study tests two types of dental implants (BIODENTOSS® and DWC®) to see how well they work and how safe they are in patients who need tooth replacement. If you have a missing tooth and want an implant, this study will track how your implant performs over time.
KonyaAges 18 years+ - NCT07788846Recruiting
Comparing methods to stop bone bleeding during finger or toe amputation
This trial tests different ways to stop bleeding from bone during finger or toe amputation surgery. It compares using collagen, bone wax, or pressure to see which works best and is safest.
Kolār, KarnatakaAges 18 years+ - NCT07817381Recruiting
Resistance and loading exercise for bone health
This trial tests a supervised exercise program with weights and jumping activities to improve bone health in males with one leg amputated below the knee. If you're already using a prosthetic leg and walking well, this study might help strengthen your bones.
LoughboroughAges 18–55 - NCT07604142Enrolling by invitation
Donor bone to close sinus opening after tooth extraction
This trial tests using sterilized donor bone to repair a hole that opens into your sinus when a severely damaged upper back tooth is removed. The goal is to rebuild the bone so a dental implant can be placed safely later.
TantaAges 20 years+ - NCT06606119Recruiting
Brain, bone marrow, and gut study after major injury
This study is looking at how the brain, bone marrow, and gut interact after a severe injury. It may help doctors understand how to better treat trauma patients.
Gainesville, FloridaAges 18–100 - NCT04070937Recruiting
Imaging findings and balance function in bilateral vestibulopathy
This study compares CT/MRI imaging results (radiological lesions) with balance system function tests in people with bilateral vestibulopathy. The goal is to see whether changes seen on scans match how well your inner-ear/balance nerves are working, which could improve understanding and future treatment decisions.
Hasselt, LimburgAges 18–90 - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+
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Common questions
- Are there clinical trials for bone loss?
- Yes. Clin2 currently lists 94 recruiting bone loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.