Clinical trials
Bone Loss clinical trials
Below are recruiting bone loss clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT04246944Recruiting
Induced membrane bone repair study in critical defects
This study looks at how a specific bone-repair technique (called induced membrane reconstruction) works in people with large “critical-sized” bone defects. It may help doctors understand the results and properties of this method in both children and adults.
AmiensAges 9 months–60 years - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT04809064Recruiting
Compare open vs arthroscopic surgery for unstable shoulder with bone loss
This trial compares two surgery approaches for people with a traumatic, unstable (dislocating) shoulder when they also have moderate bone loss. It may help identify which method restores stability better and with fewer problems for the right patients.
Tempe, ArizonaAges 17–50 - NCT05533528Recruiting
Save gum tissue in surgery for severe periodontitis
This trial studies a way to preserve gum (periodontal) “granulation” tissue during surgical treatment for severe periodontitis (gum disease). It may help patients heal better after surgery, especially when deep gum pockets do not improve after non-surgical care.
MurciaAges 18 years+ - NCT04954664Recruiting
Bone graft particles to help dental implants fit in missing teeth areas
This study tests a bone-grafting approach (using processed donor bone particles, with or without a growth factor) to help dental implants work when the jaw bone is too narrow. It may help people get implants placed more safely and effectively in areas with missing teeth.
Birmingham, AlabamaAges 18–99 - NCT05658289Recruiting
Latarjet vs shoulder bone surgery after front dislocation
This trial compares two types of surgery that rebuild the front (anterior) shoulder bone when there has been significant bone loss. It may help find which operation works better to keep your shoulder from dislocating again.
Halifax, Nova ScotiaAges 16–40 - NCT06017193Recruiting
Ultrasound to check bone healing after tooth removal and graft
This study uses ultrasound to check how well your jawbone heals after a tooth is pulled and a bone graft is placed, as part of getting ready for a dental implant. If you have a tooth that needs to be removed and you're planning to get an implant, this trial may help monitor your healing.
Columbus, OhioAges 18 years+ - NCT06022549Recruiting
Mobile health for HIV patients with metabolic and bone issues
This trial tests a mobile health program designed to help people with HIV manage metabolic syndrome and bone loss. It aims to find if text messages and health tips can improve your health.
TaipeiAges 30 years+ - NCT06151028Recruiting
Menopause Symptoms in Women After Ovary Removal for Gynecologic Cancer
This study looks at menopause symptoms in women who have had their ovaries removed as part of gynecologic cancer treatment. It aims to understand how these symptoms affect patients over time.
Hefei, AnhuiAges 18–55 - NCT06315413Recruiting
Comparing two socket preservation methods after tooth extraction
This trial compares two methods for preserving bone after a tooth is pulled in the upper front (smile) area. It tests whether a special plug or a membrane does a better job keeping the bone ready for a future implant.
Cairo, Cairo GovernorateAges 20–70 - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT06362057Recruiting
3D dental implants for severe bone loss
This trial tests a new type of dental implant that sits on top of the jawbone under the gums, which may help people who have severe bone loss in the upper jaw and cannot get regular implants.
Al MansurahAges 30–70 - NCT06447792Recruiting
Success of dental implants for lower front teeth
This trial tests how well two dental implants support a bridge or partial denture in the lower jaw when you have loose or missing front teeth. The goal is to see how long the implants last with different loading schedules.
Al MansurahAges 25–65 - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT06513039RecruitingPhase 4
Erythropoietin for preserving jawbone after tooth extraction
This trial tests whether a medicine called erythropoietin can help preserve the bone in your jaw after a tooth is pulled. It may help keep the area strong for future dental work.
CairoAges 18–40 - NCT06514677Recruiting
Nonsurgical treatment for implant infection with ultrasonic carbon tip
This study tests whether using a special ultrasonic carbon tip (a gentle cleaning tool) can treat infection around a dental implant without surgery. It is for people with a single problem implant who are otherwise healthy and have good oral hygiene.
KütahyaAges 18–99 - NCT06527664Recruiting
Custom hip implant for failed arthritis treatments
This trial tests a custom-made hip socket implant for people who have had a failed hip replacement or arthritis treatment. It aims to see if a personalized implant can provide a better solution.
BolognaAges 18 years+ - NCT06930781Recruiting
Study of Ponto implants outside of the operating room
This study looks at how well Ponto implants work when placed in a clinic or office setting instead of a hospital operating room. It is for adults who already had this procedure in 2019 or later.
Sacramento, CaliforniaAges 18 years+ - NCT06666595Recruiting
Short vs standard implant for lower partial denture
This trial tests whether a shorter dental implant placed slightly below the bone works as well as a standard-length implant placed at the bone level to hold a lower removable partial denture more securely. It may help you if you have a loose denture and enough bone for one of these implants.
Al MansurahAges 50–70 - NCT07083531Recruiting
Bone health study for older Black women with sickle cell trait
This study looks at how carrying the sickle cell trait (not the disease) affects bone density, physical function, and frailty in older African American women. It aims to help understand bone loss risk and prevent fractures.
Farmington, ConnecticutAges 50 years+ - NCT07093853Recruiting
Comparing two ways to attach a lower denture to four implants
This trial tests two ways to attach a lower denture to four dental implants: using four small clips (locators) or a single bar that connects all four implants. The goal is to find which method is more stable and comfortable for people who are completely toothless in the lower jaw.
Al Mansurah, MenoufiaAges 40–70 - NCT07102758Recruiting
Comparing gum grafts for immediate dental implants
This trial tests two ways to support the gum around a new dental implant placed right after a tooth is pulled. It compares a special blood-clot material (L-PRF) to a connective tissue graft to see which heals better.
Kafr ash Shaykh, KafrelsheikhAges 21–45 - NCT07146776Recruiting
Injectable PRF and bone graft for gum disease bone defects
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
Istanbul, ÜsküdarAges 18–65
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Common questions
- Are there clinical trials for bone loss?
- Yes. Clin2 currently lists 97 recruiting bone loss studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone loss trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone loss trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.