Clinical trials
Brain Diseases clinical trials
Below are recruiting brain diseases clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT06446505Recruiting
Decision aid for deep brain stimulation in Parkinson's
This study tests a decision aid to help people with Parkinson's disease who are being considered for deep brain stimulation (DBS) surgery. The goal is to see if the tool helps patients make more informed choices about their treatment.
Aurora, ColoradoAges 18 years+ - NCT06570681Recruiting
Video call assessment for acute stroke
This trial tests whether a video call with a doctor can help assess stroke symptoms quickly in the ambulance or emergency setting. It aims to see if this approach speeds up care and improves outcomes for people with possible stroke.
Aabenraa, Region SyddanmarkAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT07108712Recruiting
Using brain MRI to detect early white matter disease
This trial studies whether a special type of MRI can find brain white matter changes early. It might help people who have early symptoms or are at risk for diseases affecting the brain's wiring.
CairoAges 18–80 - NCT04286516Recruiting
Brain and robot training for arm movement after stroke
This study tests whether brain stimulation and robotic/arm training can improve arm movement in people who had a stroke. It may help strengthen movement and coordination by targeting brain pathways related to arm control.
Pittsburgh, PennsylvaniaAges 45–90 - NCT06959199Recruiting
Treating stroke beyond 24 hours with artery-opening procedure
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Hefei, AnhuiAges 18 years+ - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT05287750Recruiting
Brain disease study using 7.0T brain MRI scans
This study looks at people with brain conditions using a very strong MRI scanner (7.0T). It may help doctors understand brain diseases better and improve how scans are used, but you must be able to safely have the MRI (and possibly contrast dye).
BeijingAges 18–80 - NCT04222062RecruitingPhase 2
Compare Gliadel implant versus focused brain radiation
This Phase 2 study compares two ways to treat brain metastases: a Gliadel wafer placed during planned surgery versus focused stereotactic radiosurgery. It aims to see which approach works better and is safer for people with a limited number of brain tumor spots.
Detroit, MichiganAges 18 years+ - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT06543563Recruiting
Esketamine for anesthesia during Parkinson's brain surgery
This trial is testing whether a drug called esketamine (related to ketamine) can help make the anesthesia experience better for people with Parkinson's disease who are undergoing a specific brain surgery called bilateral STN-DBS. If you qualify, you would receive esketamine during your procedure to see if it improves outcomes.
Beijing, Beijing MunicipalityAges 50–80 - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT04396873RecruitingPhase 1
PET brain scan study of inflammation markers in neurodegeneration
This Phase 1 study tests a PET scan to measure inflammation-related changes in the brain using a medication called ketoprofen. It may help researchers understand which people with certain brain diseases could benefit from treatments aimed at inflammation.
Bethesda, MarylandAges 18–99 - NCT07026734Recruiting
Speech and Swallow Effects of Deep Brain Stimulation in Parkinson's
This study looks at how deep brain stimulation (DBS) affects speech and swallowing in people with Parkinson's disease. It aims to help understand changes so doctors can better support you after DBS surgery.
Gainesville, FloridaAges 45–85 - NCT06615973Recruiting
Stroke recovery and social factors study
This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.
Bethesda, MarylandAges 18–99 - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT04012411Recruiting
Testing brain fluid biomarkers in Huntington’s disease
This study looks at specific “biomarkers” (measurable signs) found in cerebrospinal fluid, to better understand Huntington’s disease. The results may help researchers track the disease and improve future tests or treatments.
MontpellierAges 18 years+ - NCT06876857Recruiting
UCF Cerebrospinal Fluid Biobank for Adults
This is a research biobank at the University of Central Florida that collects and stores cerebrospinal fluid samples for future studies. It is open to most adults who can give their consent.
Orlando, FloridaAges 18 years+ - NCT07253974Recruiting
Atrial Fibrillation Stroke Recovery Study
This study follows people who had a stroke linked to atrial fibrillation (an irregular heartbeat) and are in a rehabilitation program. Researchers want to see how recovery goes and what helps patients improve.
BarcelonaAges 18–99 - NCT07305948Recruiting
New MRI method for clearer brain images
This study tests a faster MRI technique that reduces blurring from breathing during brain scans. If effective, it could mean clearer images without needing to hold your breath.
Stockholm, SolnaAges 18 years+ - NCT02811653Recruiting
Brain movement and memory study in early dementia
This study looks at how “slower movement” and brain changes relate to memory and thinking problems in people with early dementia (and some related conditions). It may help researchers understand what brain differences go with these symptoms, using tests and an MRI scan.
AmiensAges 40–85 - NCT06936124Recruiting
Deep brain stimulation for Alzheimer's disease
This trial tests whether deep brain stimulation of a specific brain area can help people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and quality of life.
Toronto, OntarioAges 60 years+
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Common questions
- Are there clinical trials for brain diseases?
- Yes. Clin2 currently lists 336 recruiting brain diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.