Clinical trials
Brain Health clinical trials
Below are recruiting brain health clinical trials, each written for real people, not researchers. We’re tracking 232 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06016387RecruitingPhase 2
Drug combo with radiation for HER2+ breast cancer spread to spinal lining
This trial tests a combination of three targeted drugs (tucatinib, trastuzumab, and capecitabine) along with radiation to the brain or spine for people whose HER2-positive breast cancer has spread to the lining of the brain or spinal cord. The goal is to see if this treatment is safe and effective.
Ottawa, OntarioAges 18 years+ - NCT06087393Recruiting
Brain tumor surgery imaging study
This study tests a special microscope that helps surgeons see brain tumors more clearly during surgery. The goal is to see if it can help remove more of the tumor safely.
Manhasset, New YorkAges Any age - NCT06819904Recruiting
Combined talk therapy and balance rehab for mild TBI
This trial tests a new type of therapy that combines acceptance and commitment therapy (a counseling approach) with vestibular rehabilitation (exercises for balance and dizziness). It's designed for people with mild traumatic brain injury who still have symptoms like dizziness, anxiety, or memory problems.
Pittsburgh, PennsylvaniaAges 18–49 - NCT04982731Enrolling by invitation
Testing reassurance support after a concussion in teens
This study looks at whether a specific reassurance program (“Positive Assurance”) helps teens recover better after a mild concussion. Teens are checked for concussion symptoms, then assigned to different support approaches to see which helps most.
Falls Church, VirginiaAges 13–21 - NCT07162246RecruitingPhase 2
Radiosurgery for large brain tumors and metastases
This trial tests a special high-dose radiation treatment for people who have up to two large brain tumors (metastases) and possibly other smaller ones. The treatment aims to control the tumors while limiting radiation to healthy brain tissue.
Toronto, OntarioAges 18 years+ - NCT05681195RecruitingPhase 2
Zanubrutinib plus pemetrexed for recurrent brain lymphomas
This trial tests zanubrutinib (a targeted lymphoma medicine) together with pemetrexed (chemotherapy) for lymphoma that has come back or did not respond well in or around the brain. It may help shrink measurable lymphoma and improve control of disease after prior treatments.
Miami, FloridaAges 18 years+ - NCT06163625Recruiting
Brain activity and memory in treatment-resistant depression
This study looks at how the brain's frontal lobe (DLPFC) works during memory tasks in people with treatment-resistant depression. It compares brain activity between depressed patients and healthy controls using MRI and possibly a brain stimulation technique (rTMS). It aims to understand why some people don't respond to standard treatments.
Toronto, OntarioAges 18–65 - NCT06562127Recruiting
Water exercise and cognitive training for veterans with TBI
This trial tests if combining water-based exercise with cognitive training over eight months can help improve thinking and memory in veterans with a past mild or moderate brain injury. It may benefit veterans aged 50-89 who have ongoing cognitive complaints.
Palo Alto, CaliforniaAges 50–89 - NCT06697808Recruiting
Using Ultrasound to Detect Brain Issues in Children
This trial tests if a portable ultrasound can spot brain problems in children needing a head CT in the emergency room or ICU. If effective, it could offer a faster, radiation-free way to check for issues.
Charlotte, North CarolinaAges Up to 18 years - NCT06995313Recruiting
Biofeedback training for hemianopia
This trial tests a biofeedback training program for people with hemianopia (vision loss on one side) that started more than 6 months ago. The training uses visual and sound cues to help you make better use of your remaining vision.
Toronto, OntarioAges 18–90 - NCT07418775Recruiting
Meningioma Study: Genes, Health & Life
This study looks at how your tumor's genes, personal health habits, and other factors affect your long-term health after a meningioma diagnosis. You'll be asked to complete surveys about your health and experiences—no new treatments or procedures are involved.
San Francisco, CaliforniaAges 18 years+ - NCT06188364RecruitingEarly Phase 1
Helping caregivers of traumatic brain injury patients
This trial tests if mobile health support (texts and calls) helps caregivers of people with traumatic brain injury after rehab. You may join as the main caregiver if you supervise daily care and have a smartphone or can get one.
Richmond, VirginiaAges 18 years+ - NCT06897553Recruiting
ACT for Better Mental Health with Neurologic Illness
This study tests a type of talk therapy (ACT) to help people with neurological conditions like Parkinson’s, MS, or epilepsy feel better emotionally. It's for those who are struggling with depression, anxiety, or stress and are ready to work on their mental health.
BielefeldAges 18 years+ - NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT05474066Recruiting
Testing brain function changes before and after deployment
This study looks at how the brain’s attention and information-processing skills change around major military changes. It may help researchers better understand who is affected and how to support performance and recovery.
Ottawa, OntarioAges 18–65 - NCT06148324Recruiting
Wellness program for traumatic brain injury recovery
This study tests a wellness program for people who had a moderate or severe traumatic brain injury (TBI) at least a year ago. The program is done online, so you can join from home, and it aims to help you with your recovery and well-being.
New York, New YorkAges 18–70 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07473505Recruiting
Nerve block for PTSD in special operations veterans
This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.
Strongsville, OhioAges 18 years+ - NCT07355348Recruiting
Cognitive support program for brain metastases
This study is testing a program to provide step-by-step cognitive support for adults whose cancer has spread to the brain. It aims to help people think more clearly and manage any memory or attention problems.
Toronto, OntarioAges 18 years+ - NCT04197297RecruitingPhase 2
Brain scan tests for biomarkers in people with brain metastases
This trial studies brain scan findings to see if specific imaging markers can help understand or predict outcomes in people with brain metastases. It may help researchers improve how brain metastases are evaluated before radiation treatment.
Toronto, OntarioAges 18 years+ - NCT06866691RecruitingPhase 4
Seizure prevention after traumatic brain injury
This trial tests two medicines, levetiracetam and lacosamide, to see which works better at preventing seizures in people who have had a traumatic brain injury. The goal is to find the safest and most effective way to protect your brain after injury.
Winston-Salem, North CarolinaAges 18 years+ - NCT07572734Recruiting
Breathing exercises to help after a concussion in teens
This study tests whether special breathing exercises can help the nervous system recover better after a concussion. Kids ages 9–18 who come to the emergency room within 3 days of a concussion may qualify if they have symptoms like dizziness, nausea, tiredness, confusion, anxiety, or sleep problems.
Montreal, QuebecAges 9–18 - NCT05912270Recruiting
Music lessons to boost thinking skills in primary school
This trial studies whether an “orchestra in class” music program can improve kids’ thinking and brain development. It’s meant for younger primary school children and may help with skills like planning and attention.
GenevaAges 6–8
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Common questions
- Are there clinical trials for brain health?
- Yes. Clin2 currently lists 232 recruiting brain health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.