Clinical trials
Brain Health clinical trials
Below are recruiting brain health clinical trials, each written for real people, not researchers. We’re tracking 232 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05483465RecruitingPhase 4
NAD supplement trial for brain blood vessel health in aging
This trial studies whether taking an NAD supplement can support brain blood vessel health as people age. Participants will be tested for brain and health changes and may help researchers understand how to keep the brain’s blood vessels healthier over time.
Oklahoma City, OklahomaAges 60–85 - NCT06070025Enrolling by invitation
Military life experiences and psychological health study
This study looks at how experiences before joining the military affect the mental health of active-duty service members. It may help understand what supports are needed for those currently serving.
Oceanside, CaliforniaAges 18 years+ - NCT06048094RecruitingPhase 1
PET scan study for brain metastases treated with radiosurgery
This trial tests a special PET scan (18F-fluciclovine) to see how well it shows brain metastases after stereotactic radiosurgery (a precise form of radiation). It may help doctors better understand treatment effects.
Miami, FloridaAges 18 years+ - NCT06705296RecruitingPhase 1
Deep brain stimulation for severe PTSD
This trial tests whether deep brain stimulation, a surgery that uses a small device to send electrical pulses to specific brain areas, can help people with severe PTSD that hasn't improved after trying several treatments. It aims to see if this approach is safe and effective for long-lasting symptoms.
Toronto, OntarioAges 18–70 - NCT06695910RecruitingPhase 4
Testing an omega-3 supplement for brain fog
This trial tests whether a special form of omega-3 (MAG-EPA) can help people with ongoing brain fog symptoms like mental fatigue, memory loss, or trouble concentrating. If you've had these issues for at least 28 days, you may be eligible.
Maria, QuebecAges 19–55 - NCT06923722Recruiting
Can eating grapes help protect your brain during stress?
This study tests whether eating grapes every day for a few weeks can reduce the negative effects of mental stress on your brain and blood vessels. If you are a healthy young adult who experiences stress, you may be able to join.
Birmingham, West MidlandsAges 18–40 - NCT07427563Recruiting
Cerebellar deep brain stimulation for ataxia
This trial tests whether stimulating a part of the brain called the cerebellum with a device can help improve balance and coordination in people with primary ataxia (a movement disorder you were born with or inherited). It aims to see if this treatment is safe and effective over one year.
Toronto, OntarioAges 20–70 - NCT04758624Recruiting
Study brain changes after deep brain stimulation for tremor
This study looks at how brain “wiring” (connectivity) and brain function change over time in people with essential tremor after successful deep brain stimulation. You might benefit by helping researchers better understand what DBS does in the brain, which can improve care for others with tremor.
Manhasset, New YorkAges 18–85 - NCT05887934Enrolling by invitation
Bone lead levels and mental health in adults
This study looks at whether the amount of lead stored in the body (from old exposures) is linked to brain activity and mental health. It may help researchers understand what kinds of brain/mental health symptoms are related to lead exposure.
Charleston, South CarolinaAges 18–70 - NCT05622409Recruiting
Tissue and genetic data registry for diffuse glioma in adults
This study collects tumor tissue and basic medical information to better understand the genes involved in adult diffuse glioma. It may help future treatments by building a detailed research database and matching patients to study arms.
Kaohsiung CityAges 20 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT00859794Enrolling by invitation
Study brain and movement functions in people with difficult epilepsy
This study looks at how the brain and body coordination work in people with epilepsy whose seizures do not fully respond to seizure medicines. Some participants may be people who are being evaluated for a possible epilepsy surgery because tests suggest they could benefit.
Great Neck, New YorkAges 5 years+ - NCT03213002RecruitingPhase 1/Phase 2
CAPTEM pills after brain radiation for newly diagnosed glioblastoma
This trial studies whether taking two chemotherapy pills (capecitabine and temozolomide) after the initial 6-week radiation-and-chemo phase can help people with newly diagnosed glioblastoma. It aims to test safety and early effectiveness right before the usual maintenance temozolomide phase.
New York, New YorkAges 18–74 - NCT05554302RecruitingPhase 2
PET scan study for brain metastases after surgery
This trial studies how well a special PET scan tracer (18F-fluciclovine) shows amino-acid changes in brain metastases after they are surgically removed. It may help improve how doctors detect and understand brain metastases and guide follow-up treatment like targeted radiation (SRS).
Miami, FloridaAges 18 years+ - NCT07082218Recruiting
Sleep program to help teens recover from concussion
This study tests whether a sleep-focused program can help teenagers recover from a concussion. If you have ongoing symptoms after a concussion, this program might improve your sleep and speed up recovery.
Aurora, ColoradoAges 10–19 - NCT06494319Recruiting
PTSD treatment app for veterans with combat trauma
This study tests a virtual training program and mobile app to help veterans manage PTSD from combat. It aims to reduce symptoms and improve daily life.
Houston, TexasAges 18–79 - NCT03136302Recruiting
Tracking brain signals during deep brain stimulation
This study compares two ways of measuring brain activity—MRI-based brain mapping and electrical brain testing—during deep brain stimulation. It may help doctors better target stimulation to improve symptoms like movement problems or long-lasting pain.
Halifax, Nova ScotiaAges Any age - NCT03559114RecruitingPhase 3
Preventing blood clots after severe brain injury
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Calgary, AlbertaAges 18 years+ - NCT07031544Recruiting
Deep brain stimulation for severe OCD
This study tests whether implanting a small device deep in the brain—like a pacemaker for OCD—can help people whose severe OCD hasn't gotten better with standard medications and therapy.
Guangzhou, GuangdongAges 18–65 - NCT05954858Recruiting
Surgical flap to help treat glioblastoma by bypassing the blood-brain barrier
This trial tests a surgical technique that places a tissue flap near a glioblastoma surgery site to help medicines reach the brain more effectively. You might be considered if you are planning major brain tumor surgery and meet specific health, imaging, and lab requirements.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for brain health?
- Yes. Clin2 currently lists 232 recruiting brain health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.