Clinical trials · Boston, MA
Brain Injuries clinical trials in Boston
We’re tracking 22 recruiting brain injuries studies with a site in or near Boston — including Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06939348Recruiting
Ultrasound therapy for patients with consciousness disorders
This trial tests whether ultrasound stimulation can help people with disorders of consciousness, like coma or a minimally conscious state. It aims to improve brain function and recovery for patients who have been injured for over a month.
Boston, MassachusettsAges 18–79 - NCT06429007Enrolling by invitationPhase 1
Metformin for infants after brain injury from HIE
This trial tests whether metformin, a common diabetes medicine, can help heal brain injury in infants who had HIE (lack of oxygen at birth) and were treated with cooling. It aims to see if the drug is safe and possible to give to babies between 3 and 6 months old.
Boston, MassachusettsAges 3 months–6 months - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT06109909Recruiting
Brain training for light sensitivity after mild head injury
This study tests if a type of brain training called neurofeedback can help reduce sensitivity to light in people who have had a mild traumatic brain injury, also known as a concussion, at least 6 months ago.
Boston, MassachusettsAges 18–65 - NCT07277309Recruiting
Recovery after brain injury using focused ultrasound
This study tests whether focused ultrasound can help people recover from a brain injury that has left them with a disorder of consciousness. The treatment involves a non-invasive technique that uses sound waves to stimulate brain activity.
Boston, MassachusettsAges 18–79 - NCT06848140Recruiting
Brain stimulation for word-finding problems after TBI
This study tests whether non-invasive brain stimulation can help people with chronic traumatic brain injury (TBI) find words more easily. It involves sessions at Beth Israel Deaconess Medical Center in Boston.
Boston, MassachusettsAges 18–85 - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Boston, MassachusettsAges 50 years+ - NCT05724173Recruiting
Test of a brain-to-computer device for ALS hand paralysis
This study checks whether a brain-computer interface (a BrainGate2 system) is safe and workable for people with ALS. If you qualify, you may be asked to try the device and complete study tasks to help researchers learn how well it can support communication or control.
Boston, MassachusettsAges 18–80 - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Boston, MassachusettsAges 22–75 - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
Boston, MassachusettsAges 18–65 - NCT04400266RecruitingPhase 4
Buspirone and melatonin for depression after a brain injury
This trial studies whether the medicines buspirone and melatonin can reduce depression symptoms in people who had a mild or moderate traumatic brain injury (TBI) at least 3 months ago. It may help if you have ongoing depression after TBI and can safely take study medications and attend regular visits, including MRI scans.
Boston, MassachusettsAges 18–64 - NCT07131475RecruitingPhase 2
Brain injury detection in Navy SEALs with blast exposure
This study looks for early signs of brain injury in Navy SEALs who are repeatedly exposed to blasts. It uses advanced scans and biomarkers to find changes that might lead to problems later on.
Boston, MassachusettsAges 18–50 - NCT02793999Recruiting
Near-infrared monitoring to guide cooling in newborns
This study tests a special, non-invasive sensor (near-infrared light) to help doctors choose the best cooling treatment for some newborns after brain injury. It may improve how well cooling works and how safely it’s managed in the first week of life.
Boston, MassachusettsAges Up to 2 years - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT00912041Recruiting
Test of a brain-to-computer device for quadriplegia
This study tests whether a tiny brain computer interface can help people with quadriplegia (loss of movement in all four limbs) communicate or control technology. It’s mainly a feasibility study, meaning the goal is to see if the device can work safely and reliably in real life.
Boston, MassachusettsAges 18–80 - NCT06883006RecruitingPhase 1
Sleep extension study for recent concussion recovery
This trial tests whether extending sleep helps young adults recover from a recent concussion. If you are 18-35 and had your first or second concussion 2-3 weeks ago, you may be able to join.
North Andover, MassachusettsAges 18–35 - NCT07455136Recruiting
Blood test for traumatic brain injury diagnosis and monitoring
This study is testing a new blood-based test to help doctors diagnose traumatic brain injury (TBI) and track recovery or complications. If you have had a head injury and a CT scan as part of your care, you may be able to join.
Providence, Rhode IslandAges 18 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Providence, Rhode IslandAges 11–17
Hear when a new Brain Injuries trial opens near Boston, MA
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Brain Injuries trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting brain injuries studies listed above.
- Massachusetts General Hospital · 10 studies
- VA Boston Healthcare System Jamaica Plain Campus · 3 studies
- Beth Israel Deaconess Medical Center · 2 studies
- Boston Children's Hospital · 2 studies
- Boston Medical Center · 2 studies
- Spaulding Rehabilitation Hospital · 2 studies
- Boston University
- Brigham and Women's Hospital
What taking part in a brain injuries study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there brain injuries clinical trials near Boston?
- Yes. We're currently tracking 22 recruiting brain injuries studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a brain injuries study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a brain injuries trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New brain injuries studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.