Clinical trials
Brain Tumor, Primary clinical trials
Below are recruiting brain tumor, primary clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07381959Recruiting
Brain injury markers in children with brain tumors
This study looks at markers of brain injury in children with brain tumors who have or have not received radiation therapy, compared to healthy children. It aims to better understand how treatments affect the brain.
UppsalaAges Up to 17 years - NCT01535430Recruiting
Mapping brain function in people with certain brain tumors
This study uses brain “mapping” tests (with MRI and possibly other methods) to identify important brain functions near a tumor. It may help your care team plan a safer surgery by understanding which brain areas do critical tasks.
Omaha, NebraskaAges 19 years+ - NCT07617168Recruiting
Education Support for First-Time Brain Tumor Surgery Patients
This study tests whether education and support for patients having their first brain tumor surgery—and their caregivers—helps them cope better and recover more smoothly. You and your caregiver would receive educational materials and support throughout your treatment journey.
Istanbul, IstanbulAges 18 years+ - NCT07003139RecruitingPhase 1/Phase 2
BNCT for High-Grade Malignant Brain Tumors
This trial tests a special type of radiation therapy called boron neutron capture therapy (BNCT) for people with high-grade malignant brain tumors. It aims to see if BNCT is safe and effective for tumors that have not been treated or have come back after standard treatments.
HsinchuAges 18 years+ - NCT05293197RecruitingPhase 1
Safety study of repeated blood-brain barrier opening for pediatric brain tumors
This Phase 1 study tests whether a device can safely and repeatedly open the blood-brain barrier (a protective shield in the brain) in children with malignant brain tumors. It aims to help the tumor treatment work better while watching for safety issues.
ParisAges 5–17 - NCT06442748RecruitingPhase 3
Short vs long seizure medicine in brain tumor patients
This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.
Udupi, KarnatakaAges 18 years+ - NCT07338526Recruiting
Proton therapy for children with brain tumors
This trial tests if a precise type of radiation called proton therapy is safe and effective for children with certain brain tumors. It aims to reduce side effects by focusing radiation only on the tumor.
Mumbai, MaharashtraAges 6–16 - NCT05521984RecruitingPhase 1
Dapagliflozin trial for children with hard-to-treat brain tumors
This Phase 1 trial tests whether dapagliflozin (an SGLT2 medicine) can help shrink or control certain pediatric brain tumors or other solid tumors that have come back or won’t respond. It’s designed mainly to check safety and early signs of effect in children and young adults who have limited treatment options.
St Louis, MissouriAges 6–21 - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT05976490Recruiting
Support program for people newly diagnosed with brain cancer
This study tests a “NeuroPathways” support intervention for adults who are within 6 weeks of being diagnosed with a malignant (cancerous) brain tumor. It may help patients cope and navigate care during the early, stressful period after diagnosis.
Boston, MassachusettsAges 18 years+ - NCT06099743Recruiting
ASCENT Support Program for Brain Tumor Patients
This trial tests a support program called ASCENT for people recently diagnosed with a malignant brain tumor. It aims to help patients and their families adjust and manage challenges soon after diagnosis.
Boston, MassachusettsAges 18 years+ - NCT02914067Recruiting
Testing brain scan and computer measures in young brain tumor patients
This study looks at “brain biomarkers,” meaning brain signals measured on MRI and thinking/learning tests on a computer. It may help researchers understand how brain tumors affect the brain and track changes over time.
St Louis, MissouriAges 4–18 - NCT06118723Recruiting
Supramaximal vs maximal surgery for brain tumors
This trial compares removing as much tumor as safely possible (supramaximal resection) with standard maximal resection in people with high-grade glioma (an aggressive brain tumor). The goal is to see if more extensive removal improves survival and quality of life.
San Francisco, CaliforniaAges 18–90 - NCT07420543Recruiting
Liquid biopsy during brain tumor surgery with 5-ALA
This trial is studying whether a 'liquid biopsy' (a blood test) can help guide brain tumor surgery. It uses a special dye called 5-ALA to help surgeons see the tumor during surgery, and researchers will look for tumor DNA in the blood to see if it matches what is found in the tumor.
MilanAges 18 years+ - NCT06381531Recruiting
Tracing brain tumors through imaging over time
This study looks at CT or MRI scans of people with primary brain tumors to understand how these tumors change over time. It may help you if you have imaging before and after surgery or before radiation.
Mumbai, MaharashtraAges Any age - NCT06962215Recruiting
Simulation training for paramedics caring for brain tumor patients
This study tests whether training paramedics with realistic simulations can improve the hospital experience for patients with malignant brain tumors. If you are staying in neurosurgery before your diagnosis is confirmed, you may be able to join.
Brest, Brittany RegionAges 18 years+ - NCT02824731Recruiting
Proton vs photon radiation for certain brain tumors
This study compares two types of radiation—protons and photons (X-rays)—for specific brain tumors or tumor returns. It aims to see which approach works best and is safest for you, based on how much and where the radiation is delivered.
DresdenAges 18 years+ - NCT06753136Recruiting
Electrochemotherapy for internal organ tumors
This trial tests a treatment called electrochemotherapy for tumors in internal organs (like the liver or pancreas) when standard treatments are no longer possible. It uses a drug called bleomycin plus electric pulses to target cancer cells.
PadovaAges 18–99 - NCT04135807RecruitingEarly Phase 1
Implantable device test for operable brain tumor patients
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
Boston, MassachusettsAges 18 years+ - NCT07130786RecruitingPhase 2
Preventing seizures with medication for brain tumors in movement area
This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.
Boston, MassachusettsAges 18 years+ - NCT04066465Recruiting
Testing how proton therapy affects thinking in young people
This study looks at how proton radiation therapy may affect thinking, learning, and brain function in children and teens with a primary brain tumor. It uses repeated short brain/learning tests to track possible changes over time.
Dresden, SaxonyAges 8–18 - NCT07085494Enrolling by invitation
Brain training for kids after a brain tumor
This study tests if a special computer training program, which uses brain activity (neurofeedback) and thinking exercises, can help children who survived a brain tumor improve their attention and memory. If your child struggles with focus or planning after treatment, this may offer extra support.
Hong KongAges 6–18 - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06914479RecruitingPhase 1
Gene therapy and valacyclovir for recurrent brain tumors in young people
This trial tests a new gene therapy that uses two special viruses and an oral antiviral drug (valacyclovir) to treat brain tumors that have come back in children and young adults. The therapy is given right after surgery to remove the tumor, with the goal of helping your immune system fight the cancer.
Ann Arbor, MichiganAges 3–39
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Common questions
- Are there clinical trials for brain tumor, primary?
- Yes. Clin2 currently lists 125 recruiting brain tumor, primary studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor, primary trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor, primary trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.