Clinical trials
Brain Tumor clinical trials
Below are recruiting brain tumor clinical trials, each written for real people, not researchers. We’re tracking 271 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04033497Recruiting
MRI study to tell tumor from dead tissue after brain radiation
This study uses MRI scans to figure out whether an enlarging spot in the brain after stereotactic (focused) radiation is still living tumor or dead tissue. It may help doctors better understand what’s happening after radiation and guide next treatment decisions.
Boston, MassachusettsAges 18 years+ - NCT02754544Recruiting
Brain mapping during tumor surgery while you are awake
This study uses special recording sensors during brain tumor surgery to map the brain areas that control movement and speech. It may help the surgical team protect these key functions while removing the tumor.
Houston, TexasAges 18 years+ - NCT05943262Recruiting
Microscope study using tumor samples during brain tumor surgery
This study tests a special imaging microscope on tumor tissue taken during brain tumor removal surgery. The goal is to better understand brain connections and how tumor cells signal, which may improve future diagnosis or treatments.
TaipeiAges 20 years+ - NCT07698665Recruiting
Ketamine vs dexmedetomidine in scalp block for brain tumor surgery
This trial compares two medicines, ketamine and dexmedetomidine, added to a scalp nerve block during brain tumor removal surgery. The goal is to see which provides better pain control and recovery after surgery.
Cairo, GovernorateAges 20–60 - NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27 - NCT05673928RecruitingPhase 2
Tucatinib and T-DM1 for HER2-positive brain-metastasis tumors
This Phase 2 study tests tucatinib plus T-DM1 (ado-trastuzumab emtansine) in people with HER2-positive metastatic solid tumors that have spread to the brain. It aims to shrink brain and body tumors and help control cancer that is progressing in the brain.
Houston, TexasAges 18 years+ - NCT05921786Recruiting
Study brain surgery samples to map brain connections and signals
This study uses a special microscope to study how brain tissues communicate and signal. It will look at brain tissue taken during surgery (from certain tumor or brain disease cases) to better understand brain wiring and improve reading of lab signals.
TaipeiAges 18 years+ - NCT07424092RecruitingPhase 2
Virus injection for children with recurrent brain tumors
This trial is testing a virus called DNX-2401, which is injected directly into the tumor, for children and young adults with high-grade brain tumors that have come back or are hard to treat. The goal is to see if this virus can shrink or control the tumor.
UtrechtAges 1–25 - NCT05686798RecruitingPhase 1
Gene therapy plus radiation for recurring brain tumor
This early-phase study tests a “suicide gene” therapy delivered by a virus along with radiation for adults whose high-grade brain tumor has come back or grown again. The goal is to see if the treatment is safe and can help control the tumor.
Detroit, MichiganAges 18 years+ - NCT07717827Recruiting
Brain tumor surgery guided by brain wiring maps
This trial uses advanced brain scans to create a detailed map of your brain's wiring before surgery. This helps surgeons remove more tumor safely while protecting important areas that control movement, language, and vision.
Palermo, PAAges 18 years+ - NCT07274397Recruiting
Early brain scan study after glioblastoma surgery
This study tests whether it is safe and possible to do a special brain scan (nuclear imaging) within the first 3 days after surgery for glioblastoma. It may help doctors understand how well the tumor was removed and guide future treatments.
CréteilAges 18 years+ - NCT07162246RecruitingPhase 2
Radiosurgery for large brain tumors and metastases
This trial tests a special high-dose radiation treatment for people who have up to two large brain tumors (metastases) and possibly other smaller ones. The treatment aims to control the tumors while limiting radiation to healthy brain tissue.
Toronto, OntarioAges 18 years+ - NCT07126821Recruiting
Brain disease diagnosis study using vision and language
This trial tests a new computer model that combines brain MRI scans and clinical data to help diagnose brain diseases. It may help doctors make more accurate diagnoses.
Changsha, HunanAges Any age - NCT07087002RecruitingPhase 1
GPC2-CAR T cells for children and young adults with relapsed medulloblastoma
This trial tests a new type of cell therapy called GPC2-CAR T cells for children and young adults whose medulloblastoma or related brain tumor has come back or not responded to standard treatment. The goal is to see if these specially designed immune cells can find and attack the tumor.
Palo Alto, CaliforniaAges 1–30 - NCT03067467Recruiting
MRI scan study of brain tumors using special carbon imaging
This trial uses a special MRI scan that shows how “metabolism” (how cells use fuel) differs in brain tumors. It may help researchers better understand tumor biology and how tumors may respond to treatment, without using chemotherapy or radiation as part of the study.
Dallas, TexasAges 18–70 - NCT07186556Recruiting
Exercise program for fatigue in young brain tumor survivors
This study tests whether a home-based exercise program (done through video calls) can help reduce fatigue in young adult brain tumor survivors. If you’re 18–39 and struggle with tiredness after treatment, this program may help you feel better.
Houston, TexasAges 18–39 - NCT07680439RecruitingPhase 2
CAR T cell therapy study for children with DIPG brain tumor
This trial tests a new CAR T cell therapy (BCB-276) for children and young adults with a type of brain tumor called DIPG. The therapy uses your own immune cells that are specially trained to attack the cancer.
Los Angeles, CaliforniaAges 1–26 - NCT05317858RecruitingPhase 3
Open the brain’s blood barrier to treat lung cancer brain spots
This trial tests whether using focused ultrasound to temporarily open the brain’s blood barrier—plus standard immune therapy—can better treat non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to help medicines reach the brain tumor spots more effectively, while still using the usual lung cancer treatment.
Phoenix, ArizonaAges 18–100 - NCT06922487Recruiting
Tiredness study during awake brain tumor surgery
This trial looks at tiredness during awake brain surgery for tumor removal. It might help understand how awake procedures affect patients.
LundAges 18 years+ - NCT06322602Recruiting
Brain tumor biopsy with Ommaya reservoir for fluid collection
This study places a small reservoir under your scalp during a brain tumor biopsy to collect fluid samples over time. It may help doctors learn more about your tumor and how it responds to treatment.
Rochester, MinnesotaAges 18 years+ - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT06165653Recruiting
Guided meditation during radiation for brain tumors
This trial tests whether guided meditation can help people with brain tumors feel better during radiation therapy. You'll be randomly assigned to either meditation sessions or standard care, and researchers will see how it affects your well-being.
Salt Lake City, UtahAges 18 years+ - NCT06314607Recruiting
Genetic study of brain lesions
This trial looks at the genetic and molecular features of brain lesions to better understand them. It may help find new ways to diagnose or treat these conditions.
ParisAges 18 years+ - NCT07675070Recruiting
Temozolomide (Amitzo) for grade III or IV brain tumors
This trial studies a new form of the chemotherapy drug temozolomide (called Amitzo) in people with aggressive brain tumors (grade III or IV gliomas). It aims to see if the drug is safe and effective, and is for patients who need treatment for a new diagnosis or for tumors that have come back after standard care.
TehranAges 18–80
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Common questions
- Are there clinical trials for brain tumor?
- Yes. Clin2 currently lists 271 recruiting brain tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.