Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06550245Recruiting
How babies' brains respond to strangers
This trial uses safe, non-invasive methods to study how healthy babies' brains react to seeing unfamiliar people. It may help us understand early social development.
Santa Cruz, CaliforniaAges 7 months–1 year - NCT05929898Recruiting
Brain training with MRI for motivation in healthy adults
This study tests whether a special MRI technique can help people learn to control brain areas linked to motivation. It may lead to better treatments for motivational problems.
Durham, North CarolinaAges 18–45 - NCT07752433Recruiting
Brain stimulation with augmented reality for lazy eye in adults
This trial tests a new treatment for adults with lazy eye (amblyopia) that combines brain stimulation with a special vision game using augmented reality. The goal is to improve vision in the weaker eye.
Porto, Porto DistrictAges 18–40 - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT05697874Recruiting
Rare brain tumor registry for children and young adults
This study is a global registry that collects information about people with rare or hard-to-classify brain tumors (including certain genetic tumor changes). It helps researchers learn more about these tumors and may guide future studies and treatments.
Los Angeles, CaliforniaAges Up to 45 years - NCT06620679Recruiting
Brain inflammation and stress in healthy men
This study explores how inflammation in the body affects the brain's response to stress. Healthy men will have brain scans and stress tests to understand this link better.
Leuven, Flemish BrabantAges 18–45 - NCT05975606Recruiting
Brain stimulation plus cycling to improve leg movement after spinal injury
This study tests whether a non-invasive brain stimulation paired with assisted “FES” cycling can improve walking-related leg movement in people after spinal cord injury. You may be able to take part if you can already walk short distances independently and your injury is stable (non-progressive).
London, OntarioAges 18 years+ - NCT05864274Recruiting
Cognitive training for people on chemotherapy
This trial studies a phone or tablet brain-training program to help with “cancer-related cognitive impairment,” or thinking and memory problems that can happen during chemotherapy. If you’re newly diagnosed with certain gynecologic cancers and are receiving chemotherapy, this may help you see whether the training improves cognitive symptoms.
Birmingham, AlabamaAges 18–90 - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT05026060Recruiting
Test for brain blood flow imaging in children with artery disease
This study uses a special MRI method to measure how much blood is reaching the brain in children with certain artery problems. It may help doctors better assess these conditions during routine care and imaging.
ParisAges Up to 18 years - NCT04781972RecruitingPhase 4
Brain scan study of ADHD effects from methylphenidate
This study uses brain imaging (MRI) to see how methylphenidate affects brain activity in people with ADHD. It may help doctors better understand how this medicine works and who benefits most.
Baltimore, MarylandAges 6–40 - NCT04699799Recruiting
Studies how the brain processes smells
This study looks at specific parts of the brain that help connect smells with emotion. You may be able to join if you’re an adult and there are no other limits on your health.
Chicago, IllinoisAges 18 years+ - NCT03807401Recruiting
Prismatic test study to support daily independence after brain injury
This study tests a new vision-related “prismatic adaptation” task to see if it could help people with daily independence after a brain injury. Because you’d be asked to do technical testing, the main goal is to understand how the test works in healthy people.
BronAges 18–70 - NCT07749378Recruiting
Brain stimulation study for healthy decision making
This study uses gentle, non-invasive brain stimulation (like a magnetic pulse) to understand how healthy people make decisions. If you join, you will perform simple tasks while your brain activity is briefly affected, which may reveal how your choices work.
Würzburg, BavariaAges 18–40 - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT06176261RecruitingPhase 2
Datopotamab deruxtecan for breast cancer with brain spread
This trial tests a new drug called datopotamab deruxtecan for people with HER2-negative breast cancer that has spread to the brain. It looks at how well the drug works against brain metastases.
Miami, FloridaAges 18 years+ - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT07326566RecruitingPhase 2
Silevertinib and chemo for a type of glioblastoma
This trial tests a new drug, silevertinib, combined with temozolomide (a chemotherapy) for people with a newly diagnosed glioblastoma that has certain genetic markers. It aims to see if this combination works better than standard treatment for tumors with these specific features.
Birmingham, AlabamaAges 18 years+ - NCT07643493Enrolling by invitationPhase 4
Saline vs. clot-busting drug for brain bleeding drainage
This study compares two methods to clear blood from the fluid chambers in your brain after a bleed. Researchers want to see if a clot-dissolving medication (TPA) works better than standard salt solution when delivered through a drainage tube.
Lexington, KentuckyAges 18–99 - NCT07227987Recruiting
Cognitive rehab for anger in Veterans with TBI and PTSD
This study tests a cognitive rehabilitation program to help Veterans with TBI and PTSD manage anger. You and a trusted support person will participate together to learn skills to reduce anger and improve thinking.
Durham, North CarolinaAges 18 years+ - NCT07074470Recruiting
New drug combo for relapsed brain lymphoma
This trial tests a new combination of drugs (teniposide, a PD-1 checkpoint inhibitor, and selinexor) for people with relapsed or refractory primary central nervous system lymphoma. It aims to see if this three-drug approach can shrink tumors or slow the disease when previous treatments haven't worked.
Suzhou, JiangsuAges 18–75 - NCT06981156Recruiting
Study of pediatric brain and spine tumor exams
This study tests a shorter way to check the brain and nervous system in children with brain or spine tumors. It aims to see if the new exam is as good as the standard one.
Madison, WisconsinAges 1–17 - NCT06922487Recruiting
Tiredness study during awake brain tumor surgery
This trial looks at tiredness during awake brain surgery for tumor removal. It might help understand how awake procedures affect patients.
LundAges 18 years+ - NCT06752434Recruiting
Comparing two brain stimulation methods for dystonic tremor
This trial compares PSA (a type of deep brain stimulation targeting a different brain area) versus traditional STN DBS for treating dystonic tremor. It aims to see which method provides better tremor control with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–70
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.