Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06615973Recruiting
Stroke recovery and social factors study
This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.
Bethesda, MarylandAges 18–99 - NCT07686393RecruitingPhase 1
Pet scan study of brain chemical norepinephrine
This study uses a special PET scan to look at the brain chemical norepinephrine, which may be linked to mood and anxiety. It helps researchers understand how the brain works by taking detailed pictures.
Bethesda, MarylandAges 18–105 - NCT06465199RecruitingPhase 1/Phase 2
Eflornithine and AMXT 1501 for Advanced Childhood Cancers
This trial tests a combination of two drugs (eflornithine and AMXT 1501) for children and young adults with certain types of cancer that have relapsed or not responded to standard treatment, or for a specific brain tumor (DIPG) at diagnosis. The goal is to see if this drug pair is safe and effective.
Birmingham, AlabamaAges Up to 26 years - NCT07166536Recruiting
Study on mental imagery and symptom worsening after concussion
This trial tests whether mental imagery tasks can trigger or worsen headaches and dizziness in people with long-lasting symptoms after a mild traumatic brain injury or concussion. If you still have headaches or dizziness more than 3 months after your injury, this study may help understand how your brain reacts to mental exercises.
Tel AvivAges 18–74 - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT05628207Recruiting
Test of an acceptable care-scaling plan for people with brain injury
This trial looks at a care approach to see if it is acceptable and workable for adults admitted to the hospital with a traumatic brain injury. It may help improve how care is scaled and delivered after TBI.
Minneapolis, MinnesotaAges 18 years+ - NCT05916313RecruitingPhase 1
Testing a new drug for brain tumors that have stopped responding to treatment
This trial tests a new drug called BI 764532 for people with a type of brain tumor called glioma that has not gotten better with standard treatments. The drug targets a protein on the tumor cells, which might help stop the tumor from growing.
Orange, CaliforniaAges 18 years+ - NCT07757308Recruiting
Brain and heart connection in type 2 diabetes
This study looks at how type 2 diabetes affects the link between your brain and heart. Participants will undergo tests of memory, thinking, and heart function to see how these are related in diabetes.
TunceliAges 40–75 - NCT07758270Recruiting
Brain scan study for multiple sclerosis treatment switch
This study looks at how a new pill for multiple sclerosis (MS) affects brain inflammation and immune cells. It may help people who are already taking an MS medication but want to switch to a different one.
St Louis, MissouriAges 40–70 - NCT05057702Recruiting
Personalized surgery-focused treatment plan for relapsed brain cancer
This study tests a personalized treatment plan for children and young adults whose medulloblastoma or ependymoma has come back. It aims to guide doctors using new tissue from surgery or biopsy after earlier treatments are fully finished.
Los Angeles, CaliforniaAges 1–39 - NCT07759063Enrolling by invitation
Self-paced walking study for stroke or brain injury survivors
This study tests a new way to help people who have had a stroke or brain injury walk with a more even step. It uses a treadmill that adjusts to your own pace, which may improve your walking symmetry.
Omaha, NebraskaAges 19–75 - NCT07177261Recruiting
Brain synchrony study for schizophrenia
This study looks at how brain activity syncs between people with schizophrenia and others. It aims to understand social interaction differences—potentially leading to better treatments.
Los Angeles, CaliforniaAges 18–65 - NCT06015451Recruiting
Exercise for concussion symptoms and headache
This trial tests whether a carefully supervised exercise program can help people who still have headaches or other symptoms weeks after a mild head injury. If you get symptoms when you try to be active, this study may offer a structured way to help you recover.
TrondheimAges 18–65 - NCT07636304Enrolling by invitationEarly Phase 1
Brain stimulation for inflammatory bowel disease remission
This study tests whether a non-invasive device that stimulates the vagus nerve (a major nerve in your neck) can affect brain function in people whose IBD is in remission. Researchers want to understand if this stimulation might help reduce inflammation or improve symptoms in the future.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT07755397RecruitingPhase 1
Study of JBI-778 for lung, brain, and salivary gland tumors
This trial tests a new oral medication, JBI-778, in patients with certain types of lung cancer, brain tumors, or salivary gland cancer. The drug is designed to target specific genetic changes in these tumors, and the study aims to assess its safety and effectiveness.
Surat, GujaratAges 18 years+ - NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT07755670Recruiting
Brain scans to understand hidradenitis suppurativa
This study uses MRI brain scans to see if brain activity differs in people with hidradenitis suppurativa (a painful skin condition) compared to healthy volunteers. It also tracks how treatment affects the brain over 3 months.
Changsha, HunanAges 18–45 - NCT07571486RecruitingPhase 1/Phase 2
Opening the blood-brain barrier for ALS treatment
This trial tests a device that temporarily opens the barrier between the blood and brain to see if it can help slow down ALS. It may allow treatments to reach the brain more effectively.
ParisAges 18–80 - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+ - NCT07143019Recruiting
A new device for treating wide-necked brain aneurysms
This trial tests a special device (p48/64 MW HPC) to treat certain brain aneurysms that are wide-necked or have a shape that makes them hard to treat. It might help people with aneurysms that haven't ruptured or that have been treated before and are now coming back.
Phoenix, ArizonaAges 18 years+ - NCT07383649RecruitingPhase 2
Anti-CMV therapy for breast cancer with brain metastases
This trial tests a treatment targeting a common virus (CMV) in breast cancer that has spread to the brain. The goal is to see if anti-CMV therapy can shrink or slow these brain tumors.
Houston, TexasAges 18 years+ - NCT00029965Recruiting
Understanding rare storage diseases over time
This study follows people with rare genetic conditions (GM1, GM2, sialidosis, or galactosialidosis) that affect how the body breaks down certain substances in cells. Researchers track how these diseases progress to better understand them and potentially help future patients.
Bethesda, MarylandAges 1 day–100 years - NCT06690892Recruiting
How eating beef affects brain health in young adults
This study looks at how eating beef affects thinking and brain health in young adults. You will eat beef daily and have brain scans to see if there are changes in memory or focus.
Lincoln, NebraskaAges 19–24 - NCT06677424Recruiting
Building a brain wave database for healthy people
This study uses a simple, non-invasive headband to record your brain's natural electrical signals while you listen to sounds. The goal is to collect data from healthy volunteers of all ages to create a reference database. This could help doctors better understand normal brain function and detect problems more quickly in the future.
Surrey, British ColumbiaAges 6 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.