Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00029965Recruiting
Natural history of inherited metabolic storage disorders
This study follows people with certain inherited metabolic conditions (like GM1 or GM2 gangliosidosis, sialidosis, or galactosialidosis) to learn more about how these diseases progress over time. Participating may help researchers understand the conditions better, which could improve future care.
Bethesda, MarylandAges 1 day–100 years - NCT07871071Recruiting
Brain-computer interface communication device for ALS
This trial tests a brain-computer interface (BCI) device that lets people with ALS communicate using brain signals, without needing to move. It may help those who have difficulty speaking or using eye-gaze devices.
Santa Barbara, CaliforniaAges 18 years+ - NCT07619534Recruiting
Collecting Spinal Fluid from Advanced Breast Cancer Patients
This study collects spinal fluid samples from people with advanced (metastatic) HER2-positive or triple-negative breast cancer who have never had, and currently do not have, cancer spread to the brain. Researchers want to understand how cancer cells might reach the nervous system and develop better treatments.
Bethesda, MarylandAges 18–120 - NCT03819608Recruiting
Brain stimulation and rehab after mild concussion with PTSD or cognitive issues
This trial studies whether brain stimulation plus targeted brain rehabilitation can improve symptoms after a mild concussion (mTBI). You may be invited if your concussion happened at least 3 months ago and your symptoms are affecting thinking or mood, with or without PTSD.
Chicago, IllinoisAges 18–80 - NCT07796061RecruitingPhase 1
Ultrasound plus immune cells for brain tumors
This trial tests a new way to treat a type of brain tumor called diffuse midline glioma. It uses focused ultrasound to open a tiny gap in the blood-brain barrier, which may help special immune cells (T-cells) reach and attack the tumor. The goal is to see if this combination is safe and helpful.
Washington D.C., District of ColumbiaAges 3–25 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT07493447RecruitingEarly Phase 1
Imaging dye to help see brain tumors during surgery
This study tests a special dye (panitumumab-IRDye800) that helps surgeons see brain lesions more clearly during surgery. The dye attaches to a protein on cancer cells and lights up under a special camera, which may help remove more tumor safely.
Nashville, TennesseeAges 18 years+ - NCT07875257Enrolling by invitation
Brain-based therapy for recovery after a left-side stroke
This study tests a new brain-computer system that helps people recovering from a stroke in the left side of the brain. It uses your thoughts to move a device, which may help improve arm and hand movement.
Buenos Aires, EscobarAges 18–65 - NCT07764718Recruiting
Brain stimulation for adults with drug-resistant epilepsy
This trial tests a new type of brain stimulation to find and treat the area causing seizures in adults whose seizures don't improve with medication. It is done during a standard monitoring procedure to help doctors better target treatment.
Durham, North CarolinaAges 18 years+ - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT07441421Recruiting
Improved pain relief for brain tumor surgery
This study tests a combination of pain-relief methods given before, during, and after brain surgery to see if they better control pain and help you recover with fewer side effects. It's for adults having surgery to remove a brain tumor.
BeijingAges 18–65 - NCT03005132Recruiting
Study for people with newly diagnosed brain cancer (GBM)
This trial looks at people with glioblastoma (GBM), a fast-growing brain tumor, to better understand it and how treatments might work. You may be able to join if you’re in a good general health range and have not had prior cancer chemotherapy.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05238272Recruiting
tRNS device to improve mirror therapy after stroke
This trial tests a brain-stimulation device (tRNS) paired with precision mirror therapy to improve arm movement after a stroke. It may help people with moderate to mild arm weakness regain more control, but you must meet several safety and health criteria.
TaoyuanAges 35–85 - NCT05307146Recruiting
Brain activity study during treatment for epilepsy
This study measures brain activity in people with epilepsy while doctors place temporary electrodes inside the brain. It may help researchers better understand seizures and how to improve treatment.
LeuvenAges 18–90 - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60 - NCT05357456Recruiting
Study of brain and memory changes in cortisol-producing adrenal conditions
This study tracks thinking and brain changes over time in people with adrenal findings that produce too much cortisol (a stress hormone) on their own. It may help doctors understand how different treatments or watchful waiting affect the brain and cognition.
Nanjing, JiangsuAges 20–65 - NCT03832712Recruiting
Study for adults with essential tremor not helped by beta blockers
This trial looks at people with essential tremor (a shaking condition) whose usual medicine—beta blockers—didn’t work well or couldn’t be tolerated. The goal is to test a treatment approach that may improve tremor control and daily function.
GothenburgAges 18–75 - NCT05459090Recruiting
Study of how brain “brakes” work in drug-resistant temporal epilepsy
This study looks at how the brain’s natural “braking” system works in people with drug-resistant temporal lobe epilepsy. It may help researchers better understand the condition in order to improve future treatments.
Pozzilli, IserniaAges Any age - NCT05493514Recruiting
Robotic training program for walking and balance
This trial studies whether a robotic training system (called G-EO) can help people with neurological conditions improve walking and balance. It may help by testing which factors predict who benefits most, and it requires regular training sessions.
MilanAges 18 years+ - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT02426255Recruiting
Study of serious injuries and complications after trauma
This study follows people with severe injuries (including head injuries and bleeding) to better understand serious complications that can happen after trauma. Your experience may help doctors predict and prevent these complications in the future.
AngersAges 15 years+ - NCT02714387Recruiting
Study of serious complications from non-traumatic blood vessel brain problems
This study follows people who have non-injury (non-traumatic) blood-vessel-related problems in the brain to understand serious complications. It may help researchers identify risks and improve care over time.
AngersAges 15 years+ - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.