Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05993351Recruiting
Concussion assessment using MRI and blood tests
This study uses MRI scans and blood tests to measure brain recovery after a concussion. It will help doctors understand how concussions affect the brain and find better ways to diagnose them.
Hamilton, OntarioAges 9–50 - NCT05995951Recruiting
Deep brain stimulation for severe OCD
This trial tests whether deep brain stimulation (a surgical implant that sends electrical pulses to part of your brain) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with standard treatments.
Petah TikvaAges 18–75 - NCT05996432RecruitingEarly Phase 1
Using imaging to guide radiation therapy for head and neck cancer or brain tumors
This trial uses a special PET scan tracer called 18F-FMISO to see areas of low oxygen (hypoxia) in your tumor. The results may help doctors adjust your radiation plan to target those areas more precisely.
Nashville, TennesseeAges 18 years+ - NCT05996900Recruiting
Brain stimulation study for adults with epilepsy
This study uses advanced brain monitoring and noninvasive magnetic stimulation to understand how repetitive brain stimulation works in people with epilepsy who are already scheduled for hospital monitoring. It may help develop better treatments for seizures.
Stanford, CaliforniaAges 18–65 - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT06005194Recruiting
Exercise therapy via telehealth for depression after brain injury
This study tests whether an exercise program delivered through video calls can help treat major depression in people who have had a traumatic brain injury. If you are at least one year past your injury and have symptoms of depression, you may be able to join.
Seattle, WashingtonAges 18–64 - NCT06012695RecruitingPhase 1/Phase 2
Study of an oral drug for solid tumors or glioblastoma
This trial tests an oral drug called NBM-BMX for people with advanced solid tumors that have not responded to other treatments, or for people with newly diagnosed glioblastoma (a type of brain cancer). The study aims to see if the drug is safe and effective.
Kaohsiung CityAges 18 years+ - NCT06027645Recruiting
Crawling therapy for very premature infants
This trial tests if early crawling practice on a special skate can help very premature babies at risk for developmental problems. It aims to improve their movement and brain development.
ParisAges 9 months–10 months - NCT06028334Recruiting
GetUp&Go: Helping you get active after a brain injury
This study tests a program to help people with traumatic brain injury become more physically active. You would use a smartphone app and get coaching to increase your daily movement, which may improve your recovery and quality of life.
Elkins Park, PennsylvaniaAges 18 years+ - NCT06030154Recruiting
Boosting positive feelings for people with alcohol use disorder
This study tests a program designed to help people with alcohol use disorder who also struggle with low mood or anxiety. It aims to increase positive emotions, which may make it easier to reduce drinking.
Tulsa, OklahomaAges 18–65 - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT06039787Recruiting
Exercise and Brain Insulin Sensitivity Study
This study checks if exercise training changes how your brain responds to insulin. You will do ergometer (stationary bike) training, and your brain activity will be measured before and after. It's for people who are not very active now and want to see how exercise affects brain metabolism.
TübingenAges 20–65 - NCT06040905Recruiting
Coenzyme Q10 for cognitive decline with high blood sugar and muscle loss
This trial tests whether Coenzyme Q10 supplements help people with mild memory loss or Alzheimer's who also have high blood sugar and early muscle weakness. It aims to see if CoQ10 can improve thinking and daily function.
TaichungAges 50–80 - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06044922Recruiting
Using heart rate to predict brain injury after cardiac arrest
This study looks at how your heart rate changes (heart rate variability) to predict brain injury after a cardiac arrest. It may help doctors identify brain damage earlier so they can provide better care.
Brest, Brittany RegionAges 18 years+ - NCT06045455Recruiting
CT scan to tell stroke from stroke mimics
This trial is testing whether a special type of CT scan can help doctors tell the difference between a stroke and other conditions that look like a stroke (called stroke mimics). If you have a sudden neurologic symptom within the past 24 hours, this study may help get a clearer diagnosis.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06048614Recruiting
Saline enema for meconium blockage in premature babies
This trial tests if giving a saline enema helps premature babies with meconium blockage pass stool, start feeding, and improve gut and brain health. It may reduce complications and help babies grow better.
SingaporeAges 1 day–8 months - NCT06048796Recruiting
Early stopping of sedation after cardiac arrest with normal EEG
This study is testing whether it is safe to stop sedation and temperature management early in cardiac arrest patients who have a normal-looking brain wave test (EEG). If you qualify, you would stop sedation sooner than usual, which may help you wake up faster.
Arnhem, GelderlandAges 18 years+ - NCT06056115Recruiting
Tislelizumab for lung cancer with brain metastases
This trial tests a drug called tislelizumab for people with advanced lung adenocarcinoma that has spread to the brain but is not causing symptoms. It is for those who have not had prior treatment and whose tumors do not have certain gene changes.
Shijiazhuang, HebeiAges 18–75 - NCT06059690RecruitingPhase 1/Phase 2
Imaging brain tumors to guide glioblastoma treatment
This trial studies a special imaging scan that combines MRI and PET to find active tumor areas in patients with glioblastoma. It aims to see if the scan can help identify the most aggressive parts of the tumor for surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06065046RecruitingPhase 2
Baricitinib for traumatic brain bleeding
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
Xi'an, ShaanxiAges 18–80 - NCT06068582Recruiting
Keep your memory sharp and stay at work with MS
This study tests a program of physical and mental exercises designed to slow down memory and thinking problems in people with multiple sclerosis, and help them stay employed longer.
AmsterdamAges 18–67 - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.