Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06079294Recruiting
Autoimmune encephalitis and brain glucose metabolism
This study looks at how autoimmune encephalitis affects brain metabolism using a special PET scan. It aims to better understand the condition in people who were recently diagnosed.
ParisAges 18 years+ - NCT06082648Recruiting
Brain and bowel recovery after ultra-low rectal cancer surgery
This trial studies how a noninvasive brain stimulation technique (TMS) and brain scans (fMRI) might help improve bowel function and quality of life after surgery for ultra-low rectal tumors. It is for patients who have had a specific surgery (intersphincteric resection) and a temporary ileostomy.
ShanghaiAges 18–75 - NCT06083467Recruiting
Brain imaging study for Parkinson's and related disorders
This study uses brain imaging and tests to better understand Parkinson's disease and related conditions. It aims to improve diagnosis by comparing scans across different groups of people.
Philadelphia, PennsylvaniaAges 40–85 - NCT06083948RecruitingPhase 2/Phase 3
Blood pressure medicines and brain blood flow during tumor surgery
This study tests how different blood pressure medicines affect blood flow to the brain and other organs during anesthesia for brain tumor surgery. It aims to find the safest way to keep your brain healthy while you are asleep.
AarhusAges 18–75 - NCT06087393Recruiting
Brain tumor surgery imaging study
This study tests a special microscope that helps surgeons see brain tumors more clearly during surgery. The goal is to see if it can help remove more of the tumor safely.
Manhasset, New YorkAges Any age - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06088732RecruitingPhase 1/Phase 2
Exercise and ibuprofen for bipolar depression
This study tests whether acute exercise and ibuprofen can improve symptoms of bipolar depression by studying their effects on the immune system and brain circuits. It may help if you are currently in a depressive episode and can do moderate physical activity.
Tulsa, OklahomaAges 18–55 - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT06090903Recruiting
MRI Study to Understand Glioblastoma Biology Before Surgery
This study uses MRI scans to learn more about the biology of glioblastoma before and after surgery. It may help doctors understand how the tumor behaves and improve future treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT06094205Recruiting
BrainGate2 speech study for people with tetraplegia
This study tests a brain-computer interface to help people with severe paralysis communicate by decoding attempted speech or movements. It may offer a new way to interact with devices using only brain signals.
Sacramento, CaliforniaAges 18–80 - NCT06094192Recruiting
Brain stimulation to improve memory in Alzheimer's
This study tests whether a gentle, noninvasive brain stimulation technique called tACS can help improve memory in people with Alzheimer's disease or mild cognitive impairment. It may also include healthy older adults for comparison.
Boston, MassachusettsAges 50–100 - NCT06098833RecruitingPhase 2
Sildenafil for newborn brain injury after birth asphyxia
This trial tests whether a liquid form of the medicine sildenafil can help repair brain damage in newborns who had a difficult birth and were treated with cooling. If your baby meets the cooling criteria and has brain injury on an MRI, this study may offer an additional treatment option.
Montreal, QuebecAges birth–2 days - NCT06104735Recruiting
Hand training with brain and spinal cord stimulation after spinal cord injury
This study tests whether combining hand exercises with stimulation of the brain and spinal cord can improve hand function after a spinal cord injury. You would attend about 53 study visits at the Bronx VA Medical Center.
The Bronx, New YorkAges 18–85 - NCT06105892Recruiting
Eye recovery program for mild brain injury symptoms
This study tests a home-based eye exercise program for people with mild traumatic brain injury who have ongoing vision problems like blurring or trouble focusing. It aims to help your eyes work together better and reduce symptoms.
Albuquerque, New MexicoAges 18–40 - NCT06111794Recruiting
Caregiver support program for veterans with TBI
This study tests a program called REACH that helps caregivers of veterans or service members with traumatic brain injury (TBI). You'll get phone-based support and training to reduce your stress and improve your caregiving skills.
Tampa, FloridaAges 18 years+ - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT06120361Recruiting
Primary care study for early cognitive decline
This research study looks at people who have noticed problems with memory or thinking (like trouble focusing or finding words) and visit their primary care doctor for help. It aims to better understand and diagnose conditions that cause these symptoms, such as Alzheimer's disease.
MalmöAges 40 years+ - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT06126627Recruiting
Brain and voice study for teachers with vocal fatigue
This study looks at how vocal fatigue affects the brain and voice in teachers. It uses MRI and voice tests to understand these changes.
BonnAges 21–39 - NCT06128148RecruitingPhase 1
Study of JYP0322 for ROS1 fusion-positive solid tumors
This trial tests an experimental drug called JYP0322 for people with advanced solid tumors that have a specific genetic change called a ROS1 fusion. The goal is to see if the drug is safe and effective against these tumors.
Guangzhou, GuangdongAges 18 years+ - NCT06133179Recruiting
Super-resolution brain ultrasound for stroke patients
This trial tests a new 3D ultrasound technique to get clearer images of blood flow in the brain after a stroke, which could help doctors better understand and treat the damage.
Paris, Île-de-France RegionAges 18 years+ - NCT06134219Recruiting
Course for brain fatigue after Graves' disease
This study tests a course designed to help with brain fatigue (mental tiredness) that can happen after Graves' disease. It is for people whose thyroid levels are stable but who still struggle with fatigue.
GothenburgAges 18–72 - NCT06136247Recruiting
Brain & thinking tests in opioid use disorder
This study tests whether brain scans and thinking tests can help understand opioid use disorder. It is for people on stable buprenorphine or methadone treatment.
Philadelphia, PennsylvaniaAges 18–60
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.