Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06606535Recruiting
Effects of hormone therapy on thinking skills in breast cancer
This study examines how certain hormone-lowering drugs (aromatase inhibitors) used after breast cancer treatment may affect memory, thinking, and concentration. It may help patients understand potential side effects on cognitive function.
Genova, GEAges 18 years+ - NCT06613841RecruitingEarly Phase 1
Brain tumor imaging study for glioblastoma patients
This study uses special PET scans (fluciclovine and FDG) and advanced MRI to create a detailed metabolic profile of glioblastoma. It may help doctors better understand your tumor before surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06614309Recruiting
Non-invasive treatment for brain fog from long COVID
This study tests a non-invasive treatment to help with brain fog caused by long COVID. It may improve your symptoms if you have trouble thinking clearly or focusing.
Scottsdale, ArizonaAges 18 years+ - NCT06617845Recruiting
Optimizing brain stimulation for epilepsy
This study aims to find the best settings for brain stimulation devices already implanted in patients with epilepsy. It may help improve seizure control by adjusting how the device works.
Rochester, MinnesotaAges 6 years+ - NCT06618703Recruiting
Brain radiation in childhood: early hormone check
This study follows children who had brain radiation for cancer to check for early hormone changes. It aims to catch and treat any hormone problems sooner.
AngersAges 4–18 - NCT06623565Recruiting
Advanced imaging for extensive brain tumor removal
This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.
Amsterdam, North HollandAges 18 years+ - NCT06624371RecruitingPhase 1
Atovaquone with radiation for children with brain tumors
This trial tests adding atovaquone to standard radiation therapy for children with aggressive brain tumors like high-grade glioma (a fast-growing brain cancer) or medulloblastoma. The goal is to see if this drug, which targets energy production in cancer cells, can make radiation work better.
Atlanta, GeorgiaAges 2–25 - NCT06626308Recruiting
Early signs in Huntington’s gene carriers study
This study looks for early changes in the body and brain of people who carry the Huntington’s disease gene but don’t yet have symptoms. It may help find better ways to track the disease early.
GrenobleAges 18–70 - NCT06626789RecruitingPhase 1/Phase 2
Brain training to help control emotions in BPD
This study tests whether a brain-training technique (using fMRI to help you learn to control your emotions) can help people with borderline personality disorder who haven't improved with other therapies.
Freiburg im BreisgauAges 18–65 - NCT06628414Recruiting
Brain stimulation study for tinnitus relief
This study tests whether a gentle brain stimulation technique called tDCS can help people with tinnitus. Volunteers will receive either real or fake stimulation to see if it reduces tinnitus symptoms.
NottinghamAges 18 years+ - NCT06628505Recruiting
Auditory training study for people with mild brain injury
This trial tests a type of listening training to see if it can help people who have had a mild traumatic brain injury (concussion). It may improve how your brain processes sound.
San Antonio, TexasAges 18–55 - NCT06629324RecruitingPhase 2
Bone marrow cell transplant for cerebral palsy from brain hypoxia
This trial tests whether transplanting bone marrow cells can help children with spastic cerebral palsy caused by a lack of oxygen to the brain. It may improve movement and daily function.
HanoiAges 1–10 - NCT06630260RecruitingPhase 1/Phase 2
Avutometinib and Defactinib for brain tumors
This trial tests two oral drugs, avutometinib and defactinib, in people with aggressive brain tumors like glioblastoma. The goal is to see if this combination can shrink tumors or stop them from growing.
CambridgeAges 16 years+ - NCT06632236RecruitingPhase 1
Amivantamab for advanced brain tumors
This trial tests a new drug called amivantamab for people with advanced brain tumors, including glioblastoma. It aims to see if the drug can shrink or slow tumor growth.
CambridgeAges 16 years+ - NCT06633627Recruiting
Brain response study for tooth sensitivity
This study looks at how your brain responds to tooth sensitivity. Researchers will test a simple air puff on your teeth and measure brain activity to better understand nerve signals from sensitive teeth.
SheffieldAges 18 years+ - NCT06635291Recruiting
Better Diagnosis for Children with Brain Injury
This study tests new ways to evaluate children with severe brain injuries who are in a vegetative or minimally conscious state. The goal is to improve diagnosis and care for children with serious disorders of consciousness after a brain injury.
Bosisio Parini, LeccoAges 2 months–25 years - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT06664450Recruiting
Brain fog in sleep apnea
This study looks at brain fog (difficulty thinking or concentrating) in people with severe sleep apnea, both before and after starting CPAP therapy. It aims to understand how sleep apnea treatment affects brain function.
Milan, MIAges 18 years+ - NCT06666712RecruitingPhase 1
Chronic brain infusion of topotecan for recurrent glioma
This trial tests a treatment called topotecan that is delivered directly into the brain through a small tube (convection-enhanced delivery). It is for people whose IDH-mutant glioma has come back despite standard treatment. The goal is to see if this approach can help control the tumor.
New York, New YorkAges 18 years+ - NCT06667180RecruitingPhase 1/Phase 2
Low-Intensity Magnetic Stimulation for Major Depression
This study tests whether low-intensity transcranial magnetic stimulation can help treat major depressive disorder and looks at how it affects certain brain chemicals. It's for people currently getting depression treatment who are not pregnant and have no metal implants or certain health conditions.
León, GuanajuatoAges 18–60 - NCT06668077Recruiting
Impulse control training and brain stimulation for weight loss
This study tests whether a computer-based training to improve impulse control, combined with a gentle brain stimulation technique (called iTBS), can help people with excess weight. It also looks at how these treatments affect the brain using MRI scans.
GranadaAges 18–60 - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.