Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06683378RecruitingPhase 1
Parkinson's study: nerve implant during DBS surgery
This trial tests if implanting a small piece of your own leg nerve into the brain can improve Parkinson's symptoms. It is done at the same time as deep brain stimulation (DBS) surgery.
Lexington, KentuckyAges 45–75 - NCT06677840Recruiting
Probiotics and the gut-brain connection in autism
This study looks at how the gut and brain are linked in children with autism. It tests whether probiotics can help improve behavior and symptoms by studying the bacteria in the gut.
TaipeiAges 4–15 - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06673966Recruiting
Schizophrenia brain and immune health study
This study looks at how immune system health relates to brain changes in people with schizophrenia. It uses brain imaging and electrical activity tests to understand these connections.
Changsha, HunanAges Any age - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06673329RecruitingPhase 1
Brodalumab for immune-related side effects from cancer treatment
This trial tests if brodalumab, an antibody that blocks a specific immune pathway (IL-17), can help control side effects caused by immunotherapy cancer treatment. It is for people with advanced solid organ cancers who have immune-related side effects that are suspected to involve IL-17.
New York, New YorkAges 18 years+ - NCT06666712RecruitingPhase 1
Chronic brain infusion of topotecan for recurrent glioma
This trial tests a treatment called topotecan that is delivered directly into the brain through a small tube (convection-enhanced delivery). It is for people whose IDH-mutant glioma has come back despite standard treatment. The goal is to see if this approach can help control the tumor.
New York, New YorkAges 18 years+ - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06664450Recruiting
Brain fog in sleep apnea
This study looks at brain fog (difficulty thinking or concentrating) in people with severe sleep apnea, both before and after starting CPAP therapy. It aims to understand how sleep apnea treatment affects brain function.
Milan, MIAges 18 years+ - NCT06643858Enrolling by invitation
Normal Chinese Lifespan Brain Chart Study
This study creates a 'normal brain map' by taking MRI scans of healthy people of all ages. It helps doctors understand what a healthy brain looks like at different stages of life.
Beijing, Beijing MunicipalityAges 6–90 - NCT06638801Recruiting
Brain training to boost learning and development
This trial tests a brain training program to help babies born at UAB learn and develop better, focusing on those born after 35 weeks who are going home soon.
Birmingham, AlabamaAges 1 day–1 week - NCT06618703Recruiting
Brain radiation in childhood: early hormone check
This study follows children who had brain radiation for cancer to check for early hormone changes. It aims to catch and treat any hormone problems sooner.
AngersAges 4–18 - NCT05855525Recruiting
Brain scan study that uses real-time fMRI and quick prompts
This study uses an MRI brain scan that can monitor brain activity in real time while you answer brief experience questions. It’s meant to help researchers understand how brain signals relate to people’s moment-to-moment experiences.
Philadelphia, PennsylvaniaAges 18–35 - NCT06079294Recruiting
Autoimmune encephalitis and brain glucose metabolism
This study looks at how autoimmune encephalitis affects brain metabolism using a special PET scan. It aims to better understand the condition in people who were recently diagnosed.
ParisAges 18 years+ - NCT06628414Recruiting
Brain stimulation study for tinnitus relief
This study tests whether a gentle brain stimulation technique called tDCS can help people with tinnitus. Volunteers will receive either real or fake stimulation to see if it reduces tinnitus symptoms.
NottinghamAges 18 years+ - NCT06629090RecruitingPhase 2
Brain blood vessel responses to blood flow changes: younger adults
This study looks at how the brain's blood vessels respond to changes in blood flow in healthy younger adults. It helps researchers understand normal brain aging.
Madison, WisconsinAges 20–40 - NCT06629077RecruitingPhase 2
Brain blood vessel response to blood flow changes
This study looks at how blood vessels in the brain react when blood flow changes. It may help researchers understand how the brain adapts with age.
Madison, WisconsinAges 55–69 - NCT06629324RecruitingPhase 2
Bone marrow cell transplant for cerebral palsy from brain hypoxia
This trial tests whether transplanting bone marrow cells can help children with spastic cerebral palsy caused by a lack of oxygen to the brain. It may improve movement and daily function.
HanoiAges 1–10 - NCT06626789RecruitingPhase 1/Phase 2
Brain signal training to help regulate emotions
This study tests a new brain-training technique that may help people with borderline personality disorder manage their emotions better. You will do mental exercises while an MRI scans your brain, and the results will show whether this training can reduce emotional distress.
Freiburg im BreisgauAges 18–65 - NCT06624371RecruitingPhase 1
Atovaquone with radiation for children with brain tumors
This trial tests adding atovaquone to standard radiation therapy for children with aggressive brain tumors like high-grade glioma (a fast-growing brain cancer) or medulloblastoma. The goal is to see if this drug, which targets energy production in cancer cells, can make radiation work better.
Atlanta, GeorgiaAges 2–25 - NCT06628505Recruiting
Auditory training study for people with mild brain injury
This trial tests a type of listening training to see if it can help people who have had a mild traumatic brain injury (concussion). It may improve how your brain processes sound.
San Antonio, TexasAges 18–55 - NCT06630260RecruitingPhase 1/Phase 2
Avutometinib and Defactinib for brain tumors
This trial tests two oral drugs, avutometinib and defactinib, in people with aggressive brain tumors like glioblastoma. The goal is to see if this combination can shrink tumors or stop them from growing.
CambridgeAges 16 years+ - NCT06615973Recruiting
Stroke recovery and social factors study
This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.
Bethesda, MarylandAges 18–99 - NCT06606119Recruiting
Brain, bone marrow, and gut study after major injury
This study is looking at how the brain, bone marrow, and gut interact after a severe injury. It may help doctors understand how to better treat trauma patients.
Gainesville, FloridaAges 18–100
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.