Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05297617RecruitingPhase 2
Shorter hormone therapy for low-risk postmenopausal breast cancer
This Phase 2 trial studies whether women with very low-risk, hormone-receptor positive breast cancer can safely take hormone therapy for a shorter time. It may help reduce side effects if shorter treatment works as well as the longer standard plan.
LimogesAges 51 years+ - NCT05658341Recruiting
Program of exercise, nutrition, and support for breast cancer survivors
This study tests a combined program of physical activity, nutrition guidance, and supportive resources to improve quality of life for breast cancer survivors. It may help you feel better physically and emotionally after completing (or nearly completing) treatment.
La Rochelle, Charentes-maritimesAges 18–72 - NCT05744687RecruitingPhase 2/Phase 3
Letrozole plus SPH4336 versus letrozole alone for breast cancer
This study tests whether adding SPH4336 to letrozole works better than letrozole plus a placebo for treating hormone-receptor–positive, HER2-negative breast cancer in people starting first-line treatment. It may help slow cancer growth more effectively if the added drug is beneficial.
Fuzhou, FujianAges 18–75 - NCT05831397Recruiting
Study tests tiny blood “packages” during breast cancer chemotherapy
This trial studies small particles in the blood (called extracellular vesicles) in people receiving chemotherapy before surgery for breast cancer. It may help doctors learn more about what those particles can tell them during neoadjuvant treatment.
Pavia, LombardyAges 18–80 - NCT05860465RecruitingPhase 2/Phase 3
Tested blood cancer medicine with hormone therapy for breast cancer
This trial studies SPH4336 given together with standard hormone (endocrine) therapy for breast cancer that has spread or cannot be treated with surgery. It aims to see whether the combination is safer and more effective than hormone therapy alone.
Guangzhou, GuangdongAges 18–75 - NCT05862064RecruitingPhase 3
Adding an immune drug and anti-blood-vessel treatment to chemo
This study tests whether adding an immune therapy (a PD-1 antibody) plus a blood-vessel–blocking treatment to standard chemo improves outcomes for people with surgically treated triple-negative breast cancer. Everyone gets chemotherapy, but some will also get the added drugs to try to reduce cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05891093RecruitingPhase 3
Fluzoparib plus hormone therapy after surgery for breast cancer
This Phase 3 trial tests whether fluzoparib added to standard hormone (endocrine) therapy after early breast cancer surgery can improve outcomes and safety. It may help patients whose tumors are ER-positive, HER2-negative, and a specific SNF3 subtype.
Beijing, Beijing MunicipalityAges 18–70 - NCT05989347RecruitingPhase 1
Dapagliflozin with chemo for breast cancer
This trial tests whether adding the drug dapagliflozin (a pill that lowers blood sugar) to standard chemotherapy before breast cancer surgery can improve outcomes. It is for women with high insulin levels and a higher BMI who are about to start chemotherapy.
New Haven, ConnecticutAges 18 years+ - NCT06085274Recruiting
SHINE: Using a special dye to find lymph nodes after breast cancer chemo
This study tests whether a special dye called indocyanine green (ICG) can help find sentinel lymph nodes during breast cancer surgery after chemotherapy. It may offer a safer and more effective way to check if cancer has spread.
Toronto, OntarioAges 18–80 - NCT06757621RecruitingPhase 3
Shorter Radiation for Intermediate-Risk Breast Cancer
This trial is testing a shorter course of radiation (called hypofractionated radiation) to the lymph nodes around the breast area after surgery for women with intermediate-risk breast cancer. The goal is to see if this approach works as well as standard radiation while possibly reducing side effects.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07032545Recruiting
Broccoli microgreens study for obese breast cancer survivors
This trial tests if eating broccoli microgreens can improve metabolism in obese breast cancer survivors. Participants will avoid other cruciferous vegetables during the study to see how the microgreens affect their health.
Baltimore, MarylandAges Any age - NCT07137793RecruitingPhase 2
Pentoxifylline to protect the heart during breast cancer chemo
This trial tests if a medicine called pentoxifylline can help prevent heart damage caused by doxorubicin, a common chemotherapy drug for breast cancer. If you are starting doxorubicin for the first time, this study may offer added heart protection.
DamanhūrAges 18–60 - NCT07166185Recruiting
Targeted therapy before surgery for HER2+ breast cancer
This trial tests a combination of two targeted drugs (trastuzumab and pertuzumab) given as a shot under the skin before surgery for women with a specific type of breast cancer called HER2-positive. The goal is to see if this treatment works well for women in Algeria.
BlidaAges 19 years+ - NCT07208149RecruitingPhase 1/Phase 2
Study of MR001 for advanced triple-negative breast cancer
This trial tests a new drug, MR001, for people with triple-negative breast cancer that has come back or spread. It's for those who've already tried at least one type of treatment.
BeijingAges 18–75 - NCT07237256RecruitingPhase 3
Testing less chemo for HR+ HER2- breast cancer with ribociclib
This trial tests whether some people with hormone receptor-positive, HER2-negative early breast cancer can safely receive less chemotherapy when also taking the targeted drug ribociclib after surgery. You may qualify if you have a specific stage of breast cancer and are planning to take hormone therapy for at least 5 years.
AmiensAges 18 years+ - NCT00437879Recruiting
Ultrasound and MRI scans to track breast cancer response early
This study uses ultrasound and/or MRI scans to see how breast cancer responds early while you start “neoadjuvant” treatment (chemotherapy, with or without radiation before surgery). It may help doctors spot response sooner and better understand which imaging changes match treatment benefit.
Toronto, OntarioAges Any age - NCT07461454RecruitingPhase 3
Comparing YL202 to other treatments for HR+/HER2- breast cancer
This trial tests a new drug called YL202 against other treatments chosen by your doctor for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to see if YL202 works better. You may join if your cancer has spread, you've already tried chemotherapy, and you meet other health criteria.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT07600957Recruiting
Polarized Light Therapy to Ease Radiation Skin Damage
This trial tests whether a special type of light therapy can reduce skin damage and irritation that happens during radiation treatment for breast cancer. If it works, it could help patients feel more comfortable during and after their radiation therapy.
Banī SuwayfAges 35–55 - NCT05329532RecruitingPhase 1/Phase 2
Modi-1 cancer vaccine for several hard-to-treat cancers
This Phase 1/2 study tests a cancer vaccine called Modi-1 Moditope in people with advanced triple-negative breast cancer, head and neck cancer, ovarian/high-grade serous cancer, or kidney cancer. It aims to help the immune system better recognize and attack the cancer.
Brighton, DefaultAges 18 years+ - NCT06172478RecruitingPhase 2
HER3-DXd for advanced solid tumors after prior treatment
This trial tests a new targeted drug called HER3-DXd for people with several types of advanced solid tumors that have stopped responding to standard treatments. The drug is an antibody-drug conjugate, designed to deliver chemotherapy directly to cancer cells that have a protein called HER3 on their surface.
Duarte, CaliforniaAges 18 years+ - NCT05427071Recruiting
Tracking a breast cancer marker to guide lymph node surgery
This study tests a special “marker” technique to help surgeons find affected lymph nodes in the armpit after chemotherapy. It may support more targeted surgery and help avoid unnecessary removal of healthy lymph nodes.
Hong KongAges 18 years+ - NCT05721976Recruiting
Grandmother–daughter lifestyle program for certain cancer survivors
This pilot study tests a supportive program for grandmothers who finished breast, endometrial, or ovarian cancer treatment and their adult daughters. It aims to encourage healthier habits, including physical activity, using phone-based support and Spanish/English materials.
Miami, FloridaAges 21 years+ - NCT05867966Recruiting
Testing a hypnosis-based program for symptom clusters in cancer
This trial studies whether a hypnosis-based approach can help reduce a selected set of troubling symptoms in people who have finished treatment for certain early-stage (non-metastatic) cancers. It aims to understand which symptom patterns improve and how well the intervention works.
LiègeAges 18 years+
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,192 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.