Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,466 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05954442RecruitingPhase 3
Everolimus plus chemo for advanced triple-negative breast cancer
This Phase 3 study tests whether adding everolimus to chemotherapy (chosen by the treating team) can improve outcomes in advanced triple-negative breast cancer, specifically a subtype linked to PAM pathway changes. It may help patients who have not yet had treatment for advanced/metastatic disease.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05957068Recruiting
Exercise program for breast cancer after surgery
This study tests an exercise intervention for people with early-to-mid stage breast cancer soon after curative breast surgery (and after chemo and/or radiation if you had it). It may help improve recovery, physical strength, and overall wellbeing by making exercise safer and more structured during this period.
SingaporeAges 21–99 - NCT05959291Recruiting
Stopping long-term anti-HER2 therapy in stable metastatic breast cancer
This study asks whether some people with HER2-positive metastatic breast cancer who have been stable for a long time can safely stop their ongoing (maintenance) anti-HER2 treatment. It also uses blood testing and close imaging follow-up to watch for early signs that treatment needs to restart.
Miami, FloridaAges 18 years+ - NCT05964504Recruiting
Registry study for metastatic lobular breast cancer
This study collects health information from adults with invasive lobular breast cancer that has spread (metastatic) to help researchers understand factors linked to survival. Joining may help build better knowledge for future treatments and care planning.
San Diego, CaliforniaAges 18 years+ - NCT05972343Recruiting
Cooling treatment to shrink breast tumors without surgery
This trial tests a cooling-based procedure (called cryoablation) to destroy a breast cancer tumor in people who cannot or do not want surgery. It may help shrink the visible tumor without needing an operating room.
St Louis, MissouriAges 18 years+ - NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05977036Recruiting
Biomarker test to guide early treatment for HR+ HER2- breast cancer
This study uses a lab “biomarker” test to help doctors choose the best first treatment for people with HR+ (hormone-receptor positive), HER2-negative metastatic or unresectable breast cancer. The goal is to see if this biomarker-guided approach can improve which therapy you start with.
St Louis, MissouriAges 18 years+ - NCT05982093RecruitingPhase 2
Elacestrant with or without triptorelin for premenopausal breast cancer
This trial tests a new hormone-blocking pill (elacestrant) with or without a shot that temporarily stops ovaries (triptorelin) for premenopausal women with early-stage, hormone-sensitive breast cancer. It aims to find a gentler treatment option before surgery.
Badalona, BarcelonaAges 35 years+ - NCT05982496RecruitingPhase 2
PET/MRI scan for certain breast cancer types
This trial is studying if a special PET/MRI scan using a tracer called 18F FES can help doctors decide the best treatment for people with Luminal A or hormone-receptor-positive lobular breast cancer. The scan looks at estrogen receptors to see if your cancer might respond to hormone therapy.
Milan, MIAges 18 years+ - NCT05983432RecruitingPhase 1
Study of BL-B01D1 for advanced lung and other solid tumors
This trial tests an experimental drug called BL-B01D1 for people with several types of advanced solid tumors, especially non-small cell lung cancer and breast cancer. It's designed for those whose cancer has continued to grow after standard treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT05984888Recruiting
MIND diet study for women with breast cancer
This study is testing whether a special diet called the MIND diet can help women with hormone receptor-positive breast cancer who are getting treatment. The diet focuses on foods that are good for the brain, like leafy greens and berries.
Columbus, OhioAges 45–75 - NCT05989776Recruiting
Helping women with breast cancer preserve fertility
This study is testing a new way to help women with breast cancer learn about and access fertility preservation options before starting chemotherapy. It looks specifically at whether information materials are understandable and helpful for all patients, including those with intellectual disabilities.
NantesAges 18–40 - NCT06000917RecruitingPhase 2
Study of combination therapy before surgery for ER+/HER2+ breast cancer
This trial tests a combination of targeted therapies and chemotherapy given before surgery for women with a specific type of breast cancer that is both ER-positive and HER2-positive. The goal is to see if this treatment can shrink tumors and improve outcomes.
Wuhan, HubeiAges 18–75 - NCT06001086RecruitingPhase 2
Disitamab Vedotin plus Pyrotinib for HER2-positive early breast cancer
This trial tests a combination of two targeted drugs (Disitamab Vedotin and Pyrotinib) for people with HER2-positive early breast cancer. It aims to see if this treatment can improve outcomes before standard therapy.
Nanjing, JiangsuAges 18 years+ - NCT06001528Recruiting
Predicting lymph node spread in breast cancer
This study looks at whether substances called metabolites in your blood and breast tissue can help predict if breast cancer has spread to the first lymph node (sentinel node). If you are scheduled for breast cancer surgery and have not had prior treatment, the study team will use your blood and tissue samples to try to improve prediction.
Shantou, GuangdongAges 18 years+ - NCT06006390RecruitingPhase 1/Phase 2
CAR-T therapy for CEA-positive advanced solid tumors
This trial tests a new treatment called CAR-T cells that are designed to find and attack cancer cells carrying a protein called CEA. It is for people with advanced colorectal, esophageal, stomach, or pancreatic cancer who have already tried other treatments.
Taiyuan, ShanxiAges 18 years+ - NCT06006806Recruiting
Proton therapy skin effects study for breast cancer
This study looks at how proton therapy affects the skin in people being treated for early-stage breast cancer. It aims to understand skin reactions better so doctors can reduce side effects.
Knoxville, TennesseeAges 18 years+ - NCT06027632Recruiting
Brain training at home to help with chemo brain after breast cancer treatment
This study tests a supervised computer-based mental exercise program to help reduce memory and thinking problems after chemotherapy. It is for people who finished chemo for early-stage breast cancer and still have bothersome mental fogginess.
BordeauxAges 1.5 years+ - NCT06028724Recruiting
Looking for cancer mutations using a blood test
This study uses a blood test (liquid biopsy) to find genetic changes in advanced solid tumors. It may help doctors choose the right treatment and monitor how well it works over time.
Aviano, PordononeAges 18 years+ - NCT06035016Recruiting
Pyrotinib and capecitabine after surgery for HER2+ breast cancer
This study tests whether taking pyrotinib (a daily pill) with capecitabine (another pill) after breast cancer surgery can help prevent HER2-positive early-stage breast cancer from coming back. It is for women who have already had their cancer removed and meet certain risk criteria.
Beijing, Beijing MunicipalityAges 18–75 - NCT06039644Recruiting
Probiotics for breast cancer patients on chemotherapy
This trial tests whether taking a probiotic supplement can help breast cancer patients going through chemotherapy. If you are between 20 and 80 years old, have stage I-III breast cancer, and are receiving certain chemo drugs, this study may be for you.
TaipeiAges 20–80 - NCT06042894RecruitingPhase 2
Study of two drugs for advanced HER2-negative breast cancer
This trial tests two experimental drugs, SI-B003 and BL-B01D1 plus SI-B003, for people with HER2-negative breast cancer that has spread or cannot be removed by surgery. It is for those who have tried standard treatments or cannot have them.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06044623RecruitingPhase 3
Tailoring cancer pill dosing for older adults with breast cancer
This trial is testing whether adjusting the dose of a targeted therapy (CDK 4/6 inhibitor) based on a geriatric assessment can be as effective and safer for people aged 70 and older with advanced hormone receptor-positive, HER2-negative breast cancer. It aims to find the best dose to balance benefits and side effects.
HelsinkiAges 70 years+ - NCT06052488Recruiting
Strength After Breast Cancer
This study tests a strength training program for women who have finished primary treatment for early-stage breast cancer. The goal is to see if it helps improve muscle strength and overall recovery.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,466 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.