Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 849 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07322094RecruitingPhase 1/Phase 2
Study of TORL-1-23 plus chemo before surgery for advanced ovarian cancer
This trial tests a new drug, TORL-1-23, given with chemotherapy before surgery for women with advanced ovarian cancer. It aims to see if this combination is safe and effective in shrinking tumors before they are removed.
Fullerton, CaliforniaAges 18–75 - NCT07542171Recruiting
Outcomes after incomplete early colon cancer removal
This study follows patients who had early colon cancer removed by endoscopy (a camera procedure) but the removal was incomplete. Researchers will track what happens when patients either have surgery afterward or are closely watched instead, to understand the best next steps.
Guangzhou, GuangdongAges 18–75 - NCT05827523RecruitingPhase 3
Surgery for ovarian cancer with or without heated chemotherapy
This trial studies whether adding a special heated chemotherapy treatment during surgery (called HIPEC) improves outcomes for some people with ovarian, fallopian tube, or primary peritoneal cancer. It compares surgery alone versus surgery plus HIPEC after you’ve had chemotherapy first.
Sejong, Chungcheongnam-doAges 18–80 - NCT03623958Recruiting
Image-guided minimally invasive lung surgery versus standard surgery
This study compares an image-guided version of a minimally invasive lung surgery to the standard approach for removing small lung nodules. It may help doctors improve planning and targeting of the nodule during surgery.
Boston, MassachusettsAges 18 years+ - NCT05429099Recruiting
Planning study for jaw reconstruction surgery
This study helps teams plan surgery for people who need part of the lower jaw removed and rebuilt using special tissue flaps. It mainly looks at whether having specific pre-surgery CT images is possible and useful for reconstruction planning.
Vancouver, British ColumbiaAges 18 years+ - NCT03711890Recruiting
Advanced imaging to detect early pancreatic cancer during surgery
This study tests a special high-resolution camera that can see tiny details during pancreatic surgery to help doctors detect early-stage pancreatic cancer or precancerous growths called IPMNs. The goal is to improve how well surgeons can identify and remove diseased tissue.
Columbus, OhioAges 18 years+ - NCT07788196RecruitingPhase 2
Adding anti-HER2 therapy after surgery for early-stage gastric cancer
This trial tests whether adding a targeted therapy (anti-HER2) to standard chemotherapy after surgery can improve outcomes for people with early-stage gastric cancer that has high HER2 levels. It aims to see if the combination is more effective than chemotherapy alone.
Xi'an, ShaanxiAges 18 years+ - NCT06037980RecruitingPhase 2/Phase 3
Chemotherapy before surgery for high-risk bile duct cancer
This trial tests whether receiving chemotherapy (cisplatin, gemcitabine, and nab-paclitaxel) before surgery can improve outcomes for people with high-risk bile duct or gallbladder cancer. It compares this approach to going straight to surgery.
AnconaAges 18–75 - NCT06652672Recruiting
Sentinel Node and Organ-Sparing Surgery for Early Colon Cancer
This trial tests a less invasive surgery approach for early-stage colon cancer. It uses a special dye to find and remove only the first lymph node (sentinel node) while removing just the part of the colon with the tumor, possibly avoiding a bigger surgery.
AmersfoortAges 18 years+ - NCT06392997Recruiting
Saliva test for gynecologic conditions before surgery
This study is testing a simple saliva sample to see if it can help detect gynecologic conditions (like endometriosis, fibroids, or ovarian/uterine/cervical cancer) before or during surgery. If you are having surgery or a biopsy for one of these issues, your saliva may help improve diagnosis.
AngersAges 18 years+ - NCT05633654RecruitingPhase 3
Test drug combo versus standard care for triple-negative breast cancer
This trial tests a cancer antibody-drug combination plus pembrolizumab (immunotherapy) versus standard treatment. It’s for people with triple-negative breast cancer that still has invasive disease in the breast or lymph nodes after surgery and chemotherapy before surgery.
Birmingham, AlabamaAges 18 years+ - NCT06498635RecruitingPhase 3
Immunotherapy after surgery for lung cancer with no remaining cancer
This trial tests whether giving immunotherapy (durvalumab) after surgery can help prevent lung cancer from coming back if you already had a complete response to chemo and immunotherapy before surgery. It is for people with early-stage non-small cell lung cancer who had no cancer left after treatment.
Jonesboro, ArkansasAges 18 years+ - NCT07436793RecruitingPhase 2
Progestin therapy before hysterectomy for endometrial cancer
This trial tests whether taking progestin (a hormone medication) before scheduled surgery can improve outcomes for women with a type of uterine cancer called endometrioid adenocarcinoma. You might be able to join if you are planning to have a hysterectomy and are open to hormone therapy before the procedure.
Iowa City, IowaAges 18 years+ - NCT02102477Recruiting
Surgery or radiation for prostate cancer in the pelvis
This trial compares surgery versus radiation for men with locally advanced prostate cancer that has not spread to distant sites. It aims to see which treatment works better and is easier to manage for people like you.
AalborgAges 18–75 - NCT05501353Recruiting
Study tumor biomarkers in recurrent metastatic colon cancer
This study looks for blood/tumor signals (“biomarkers”) that may help predict outcomes in people whose colorectal cancer returns and spreads after surgery. It mainly helps researchers understand who may do better or worse, which can guide future care.
Hangzhou, ZhejiangAges 18–99 - NCT06627634Recruiting
Surgery for stomach cancer that spread to the liver
This trial tests if removing the stomach tumor and liver spots together can help people with stomach cancer that has spread only to the liver. It is for those who are healthy enough for surgery and chemotherapy.
Aarhus, JyllandAges 18 years+ - NCT06598761Recruiting
Immunotherapy plus radiation after surgery for advanced UTUC
This trial is testing whether adding immunotherapy and radiation after surgery can improve outcomes for people with advanced upper tract urothelial cancer (UTUC) who cannot have chemotherapy. It compares the combination to surgery alone.
BeijingAges 18–80 - NCT07427043RecruitingPhase 3
Opioid-free pain plan for robotic prostate surgery
This trial tests a pain management strategy that avoids opioids during and after robotic prostate surgery. It aims to reduce opioid use and side effects while keeping you comfortable.
Boston, MassachusettsAges 45 years+ - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT07135817Recruiting
Pre-surgery radiation for spinal tumors
This trial tests whether giving focused radiation before surgery can improve treatment for spinal tumors that have spread from other cancers. It may help people who need surgery for a spinal tumor and have a life expectancy of more than 6 months.
GöttingenAges 18 years+ - NCT07073365RecruitingPhase 2
Adding local therapy after osimertinib plus chemo for EGFR lung cancer
This trial tests whether directly treating the remaining lung tumor with surgery or radiation, after initial chemo and osimertinib, can improve outcomes for people with advanced EGFR-mutant non-small cell lung cancer.
BusanAges 20 years+ - NCT04809025Recruiting
Testing biopsy samples vs surgery samples for stomach cancer testing
This study compares two ways of getting stomach cancer tissue: a camera-guided biopsy and a tissue sample taken during planned stomach surgery. The goal is to see which sample better supports molecular (gene-based) testing to guide diagnosis.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06258863Enrolling by invitation
Comparing incision types in breast reconstruction after mastectomy
This study compares different types of surgical cuts (incisions) used during breast reconstruction after mastectomy. It looks at which incision gives the best cosmetic result and causes the fewest problems. Researchers want to find out which technique is best for you.
Wuhan, Hongshan DistrictAges 18 years+ - NCT06071507Recruiting
Comparing treatments for stomach blockage in pancreatic cancer
This trial compares three ways to relieve a stomach or duodenal blockage caused by pancreatic cancer: placing a stent, performing a bypass with a thin tube (endoscopy), or surgical bypass. It aims to find which option helps patients eat and feel better sooner.
ParisAges 18 years+
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Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 849 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.