Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 861 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07651553Recruiting
Transanal vs. Robotic Surgery for Rectal Cancer
This trial compares two surgical approaches to remove rectal cancer while preserving bowel function. Researchers want to see which method—performed through the anus or with robotic assistance—leads to better outcomes and quality of life.
Guangzhou, GuangdongAges 18–75 - NCT05894083RecruitingPhase 2
PET-Scan Tailored De-escalation for p16+ throat cancer
This trial tests a treatment plan that may lower (de-escalate) therapy intensity for certain p16+ or HPV-positive throat cancers. It uses PET scan results and tumor features to try to keep cancer control while reducing side effects.
Ann Arbor, MichiganAges 18 years+ - NCT05542706Recruiting
Extra support for caregivers after head and neck cancer surgery
This trial tests whether adding “paramedical” support (extra practical health help) for caregivers improves care after a patient has curative surgery for certain head and neck cancers. It’s designed for patient–caregiver pairs and may help families during the stressful period around surgery and follow-up treatment.
RouenAges 18–85 - NCT05492136Recruiting
Radiofrequency during liver surgery to reduce cancer coming back
This study looks at whether using radiofrequency (a heat-based treatment used during surgery) during liver surgery can lower the chances that cancer returns locally. It includes people with colorectal cancer that has spread to the liver and people with liver cancer (HCC).
BarcelonaAges 18 years+ - NCT06284070Recruiting
Comparing FDG and FAPI PET scans for cancer
This study compares two types of PET scans (FDG and FAPI) in people with suspected or newly diagnosed cancer. It aims to learn which scan gives better images of different cancers, potentially helping guide treatment decisions.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07616310Recruiting
Removing vs. Cutting Ovarian Cancer from the Bowel
This study compares two surgical approaches for removing advanced ovarian cancer that has attached to the rectosigmoid (lower bowel). Both methods aim to remove the cancer safely, but this trial tests whether one approach works as well as the other.
Hangzhou, ZhejiangAges 18–70 - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT04630496Recruiting
Walk Test Before Lung Surgery for Older Adults
This study is looking at a “walk and movement” challenge for older adults preparing for thoracic (chest) surgery. It may help the team understand mobility and support safer care before surgery.
Boston, MassachusettsAges 65 years+ - NCT07087366Recruiting
Enhanced recovery after gynecologic cancer surgery
This trial tests a program to help women recover faster after surgery for cervical, uterine, or ovarian cancer. It focuses on improving recovery steps to reduce hospital stay and make the process smoother.
DhakaAges 18–70 - NCT05984485RecruitingPhase 3
Surgery vs chemo before surgery for low-risk rectal cancer
This trial compares two approaches for low-risk locally advanced rectal cancer: going straight to surgery (TME) versus receiving chemotherapy before surgery. The goal is to see if upfront surgery works just as well, sparing patients from chemotherapy side effects.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT04665882Recruiting
Prediction tool for arm swelling after breast cancer surgery
This trial tests a prediction tool (a “nomogram”) to estimate who is at risk of developing breast cancer–related lymphedema, or long-term arm swelling, after surgery. If you fit the surgery and lymph node criteria, your information may help personalize follow-up and prevention.
Wuhan, HubeiAges 18–80 - NCT06375798Recruiting
Breast conservation with radiation during surgery for early breast cancer
This trial is for women aged 55 or older with very early-stage breast cancer (stage 0 or 1) who want to save their breast. It tests giving a single dose of radiation during the lumpectomy instead of weeks of daily radiation afterward.
Shijiazhuang, HebeiAges 55 years+ - NCT07313579Recruiting
Heated chemotherapy for stomach cancer during surgery
This trial tests giving heated chemotherapy directly into the belly during surgery for stomach cancer. It might help people with cancer that has spread to the lining of the belly but not to other organs.
KyivAges 18–80 - NCT07322094RecruitingPhase 1/Phase 2
Study of TORL-1-23 plus chemo before surgery for advanced ovarian cancer
This trial tests a new drug, TORL-1-23, given with chemotherapy before surgery for women with advanced ovarian cancer. It aims to see if this combination is safe and effective in shrinking tumors before they are removed.
Fullerton, CaliforniaAges 18–75 - NCT07542171Recruiting
Outcomes after incomplete early colon cancer removal
This study follows patients who had early colon cancer removed by endoscopy (a camera procedure) but the removal was incomplete. Researchers will track what happens when patients either have surgery afterward or are closely watched instead, to understand the best next steps.
Guangzhou, GuangdongAges 18–75 - NCT05827523RecruitingPhase 3
Surgery for ovarian cancer with or without heated chemotherapy
This trial studies whether adding a special heated chemotherapy treatment during surgery (called HIPEC) improves outcomes for some people with ovarian, fallopian tube, or primary peritoneal cancer. It compares surgery alone versus surgery plus HIPEC after you’ve had chemotherapy first.
Sejong, Chungcheongnam-doAges 18–80 - NCT03623958Recruiting
Image-guided minimally invasive lung surgery versus standard surgery
This study compares an image-guided version of a minimally invasive lung surgery to the standard approach for removing small lung nodules. It may help doctors improve planning and targeting of the nodule during surgery.
Boston, MassachusettsAges 18 years+ - NCT05429099Recruiting
Planning study for jaw reconstruction surgery
This study helps teams plan surgery for people who need part of the lower jaw removed and rebuilt using special tissue flaps. It mainly looks at whether having specific pre-surgery CT images is possible and useful for reconstruction planning.
Vancouver, British ColumbiaAges 18 years+ - NCT05597683Recruiting
Nerve block for pain after major abdominal cancer surgery
This trial studies whether a targeted nerve block (called a quadratus lumborum block) can improve pain control after cytoreductive surgery and heat-based chemotherapy put into the abdomen (CRS and HIPEC). It may help some people use less rescue pain medicine and feel more comfortable during recovery.
SeoulAges 19 years+ - NCT03711890Recruiting
Advanced imaging to detect early pancreatic cancer during surgery
This study tests a special high-resolution camera that can see tiny details during pancreatic surgery to help doctors detect early-stage pancreatic cancer or precancerous growths called IPMNs. The goal is to improve how well surgeons can identify and remove diseased tissue.
Columbus, OhioAges 18 years+ - NCT06037980RecruitingPhase 2/Phase 3
Chemotherapy before surgery for high-risk bile duct cancer
This trial tests whether receiving chemotherapy (cisplatin, gemcitabine, and nab-paclitaxel) before surgery can improve outcomes for people with high-risk bile duct or gallbladder cancer. It compares this approach to going straight to surgery.
AnconaAges 18–75 - NCT06652672Recruiting
Sentinel Node and Organ-Sparing Surgery for Early Colon Cancer
This trial tests a less invasive surgery approach for early-stage colon cancer. It uses a special dye to find and remove only the first lymph node (sentinel node) while removing just the part of the colon with the tumor, possibly avoiding a bigger surgery.
AmersfoortAges 18 years+ - NCT06392997Recruiting
Saliva test for gynecologic conditions before surgery
This study is testing a simple saliva sample to see if it can help detect gynecologic conditions (like endometriosis, fibroids, or ovarian/uterine/cervical cancer) before or during surgery. If you are having surgery or a biopsy for one of these issues, your saliva may help improve diagnosis.
AngersAges 18 years+ - NCT05633654RecruitingPhase 3
Test drug combo versus standard care for triple-negative breast cancer
This trial tests a cancer antibody-drug combination plus pembrolizumab (immunotherapy) versus standard treatment. It’s for people with triple-negative breast cancer that still has invasive disease in the breast or lymph nodes after surgery and chemotherapy before surgery.
Birmingham, AlabamaAges 18 years+
Hear when a new Cancer Surgery trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 861 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.