Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06980077RecruitingPhase 2
Ivonescimab for advanced thymic carcinoma
This trial tests a new drug called ivonescimab for thymic carcinoma that has come back or isn't responding to other treatments. It aims to see if this drug can shrink the cancer and help you feel better.
Davis, CaliforniaAges 18 years+ - NCT07287748RecruitingPhase 1
Studying AF-001 for advanced thyroid cancer
This trial tests a new drug called AF-001 for people with thyroid cancer that has spread and can't be removed with surgery. It's for those who didn't benefit from or can't take standard treatments, or who haven't had radioactive iodine therapy yet.
KashiwaAges 18 years+ - NCT07622953Recruiting
Vaginal Fluid Markers for Early Detection of Gynecological Cancer
This study collects vaginal fluid samples to test whether certain biological markers (substances in the fluid) can help detect gynecological cancers earlier or track how they change during treatment. You may qualify if you're being evaluated for, currently receiving treatment for, or receiving comfort care for a gynecological cancer.
SouthamptonAges 18 years+ - NCT05073848Recruiting
Study how activity affects fatigue in cancer survivors
This study looks at whether physical activity changes different ways cancer fatigue shows up in people who are currently in cancer treatment or recently finished. You may be able to join if you’re already in the BfitBwell Cancer Exercise Program and have enough fatigue to measure meaningful changes.
Aurora, ColoradoAges 18 years+ - NCT05759546RecruitingPhase 2
Test a PARP and CDK4/6 medicine plus hormone therapy
This Phase 2 study tests whether combining a PARP inhibitor with a CDK4/6 inhibitor and hormone (endocrine) therapy can help people with advanced HR-positive, HER2-negative breast cancer. It’s for certain patients who have not yet had chemotherapy or targeted therapy for metastatic disease.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06496295Enrolling by invitation
Testing a new speculum for cervical cancer screening
This trial tests a new kind of vaginal speculum (the tool used to look inside the vagina during a pelvic exam). It is for people who have never had this exam before, to see if it works well for cervical cancer screening.
Englewood, ColoradoAges 18–65 - NCT07441369Enrolling by invitationPhase 2
Abemaciclib with chemotherapy for advanced colorectal liver metastases
This trial tests combining the targeted drug abemaciclib with standard chemotherapy (FOLFOX or FOLFIRI) for people whose colorectal cancer has spread to the liver and cannot be removed surgically. It may be an option if you've already tried two or three prior treatments without success.
ShanghaiAges 18–75 - NCT06943781Recruiting
Gastric cancer screening using high-risk gene detection
This trial is testing a new way to identify people at higher risk for stomach cancer using a gene test for Helicobacter pylori. It may help detect cancer early in people aged 40 and older.
TonglingAges 40 years+ - NCT06547710Recruiting
Surgery for lung cancer that has spread to the lining of the lung
This trial tests if removing the main lung tumor can help patients whose cancer has spread to the lining of the lung (M1a stage) but not to other organs. It is for people who have not had any prior treatment for lung cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06875258RecruitingPhase 4
Penile rehab after nerve-sparing prostate surgery
This trial tests a penile rehabilitation program for men who have nerve-sparing prostate cancer surgery. It aims to help improve erections and sexual function after the procedure.
Nijmegen, GelderlandAges 18–70 - NCT03125980RecruitingPhase 3
Chemo timing before vs after colon cancer surgery
This Phase 3 study compares two schedules of a colon cancer chemo combination: starting before surgery or starting after surgery. It aims to see which timing helps people live longer and lowers cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05837039Recruiting
Comparing caregiver and nurse views of discomfort in advanced cancer
This study compares how healthcare providers and family caregivers judge discomfort in people with advanced cancer who are very hard to rouse and may be actively dying. It aims to understand whether caregiver and staff perceptions match, which could improve comfort care for patients near the end of life.
Houston, TexasAges 18 years+ - NCT05788744Recruiting
Testing DNA-based blood tests in early pancreatic cancer
This study looks at DNA signals from blood tests (so-called “ctDNA” and another type of DNA test) in people with early-stage pancreatic cancer. It aims to see whether these tests can help track cancer after surgery and check for signs of return.
AalborgAges Any age - NCT06876610Recruiting
Blood test for early breast cancer detection
This trial tests a blood test that looks for chemical changes in DNA to help diagnose breast cancer. It may offer a simpler way to detect cancer without needing a tissue sample.
Beijing, Beijing MunicipalityAges 30–75 - NCT05841472RecruitingPhase 2
Camrelizumab plus chemo for advanced lung cancer without EGFR or ALK
This Phase 2 trial tests whether the immunotherapy drug camrelizumab, combined with pemetrexed and carboplatin, can work better as first treatment for advanced lung cancer that has no EGFR or ALK gene changes. You may be able to join if you have measurable disease, good enough organ function, and meet other safety rules for immune treatment.
AnamAges 19–80 - NCT05843877RecruitingPhase 3
Surgery choice and insulin islet transplant to prevent leaks
This Phase 3 trial studies a pancreatic surgery approach (pylorus-preserving Whipple or similar) and, in some cases, moving your insulin-making cells into your body to help prevent a dangerous post-surgery leak from the pancreas. It may help people who are considered high risk for this complication based on pancreas texture and duct size.
DresdenAges 18 years+ - NCT07595237RecruitingEarly Phase 1
Radioactive treatment for advanced solid tumors with Claudin18.2
This early-stage trial tests a new radioactive drug (177Lu-DOTA-SNA040) designed to target a protein called Claudin18.2 found on certain cancer cells. The drug delivers radiation directly to tumors in patients with advanced gastric, pancreatic, or bile duct cancers that have stopped responding to standard treatments.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06881537RecruitingPhase 2
Chemo and targeted therapy before surgery for recurrent colorectal cancer
This trial tests a combination of chemotherapy (CapeOX), a targeted drug (bevacizumab), and an immunotherapy (anti-PD1) given before surgery for colorectal cancer that has come back locally (in the same area). The goal is to shrink the tumor and improve surgical outcomes.
ShanghaiAges 18–75 - NCT06941324Recruiting
Therapy to help teens and young adults with cancer feel better
This study tests a short-term therapy called Solution-Focused Brief Therapy to help teens and young adults with cancer reduce emotional distress. It's designed for people who are currently in treatment or have finished treatment within the last 5 years.
Ann Arbor, MichiganAges 15–39 - NCT06545955RecruitingPhase 3
Gene therapy study for high-grade bladder cancer not responding to BCG
This trial tests a gene therapy called nadofaragene firadenovec, given directly into the bladder, either alone or with chemo or immunotherapy. It's for people with high-grade bladder cancer that hasn't gone away after BCG treatment.
Tucson, ArizonaAges 18 years+ - NCT07124546Recruiting
Acceptance and commitment therapy for cancer distress
This trial tests a type of counseling called acceptance and commitment therapy (ACT) to help people with incurable cancer feel less distressed. It is done in a group over the internet, so you can join from home.
Rochester, MinnesotaAges 18 years+ - NCT06008119RecruitingPhase 3
Targeted pill combination for BRAF-mutated metastatic colorectal cancer
This study tests a combination of two targeted pills (tunlametinib and vemurafenib) for people with metastatic colorectal cancer that has a specific gene change (BRAF V600E) and whose cancer has grown after at least one prior treatment. The goal is to see if this drug combination can shrink tumors or slow cancer growth.
Beijing, Beijing MunicipalityAges 18–70 - NCT06774222RecruitingPhase 2
Fruquintinib plus chemo for HER2-negative gastric cancer
This trial tests adding fruquintinib (a targeted drug that blocks blood vessel growth) to chemotherapy after surgery for HER2-negative stomach or gastroesophageal junction cancer. It is for patients whose tumor did not respond well to previous treatment before surgery.
ZhengzhouAges 18–75 - NCT06722612Recruiting
Chemo plus targeted therapy for high-risk HER2+ early breast cancer
This trial tests whether combining chemotherapy with targeted therapy works better for women with high-risk, HER2 positive early breast cancer that hasn't spread to lymph nodes. If you've had surgery and your tumor fits certain high-risk features, you may be eligible to join.
Beijing, Beijing MunicipalityAges Any age
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.