Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,114 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07617025Recruiting
Understanding Breast Cancer Subtypes in BRCA Carriers
This study examines how different molecular subtypes (patterns of genes and proteins) of breast cancer behave in people with BRCA1 or BRCA2 mutations. By studying tumor samples and medical records, researchers hope to better predict which treatments will work best and predict long-term outcomes for BRCA-positive breast cancer patients.
GenovaAges 18 years+ - NCT07619235RecruitingPhase 4
Combination immunotherapy and chemotherapy for advanced bile duct cancer
This study tests a combination of four drugs—two immunotherapy drugs (iparomlimab and toripalimab), a targeted therapy (bevacizumab), and chemotherapy—as a first-line treatment for advanced biliary tract cancer (cancer of the bile ducts or gallbladder). The goal is to see if this combination can shrink tumors and help patients live longer.
Wuhan, HubeiAges 18–75 - NCT07616648Recruiting
How Opioid Pain Drugs Affect Sleep and Mood in Cancer Patients
This study examines how opioid medications (strong pain relievers) impact sleep quality and emotional well-being in cancer patients with moderate to severe pain. Researchers will track your sleep patterns and mood to better understand these side effects.
HangzhouAges 18–75 - NCT07615374Recruiting
Combined laparo-endoscopic sentinel node surgery for early stomach cancer
This trial tests a surgical technique that combines two types of minimally invasive procedures (laparoscopy and endoscopy) to find and remove the first lymph node that might contain cancer (called the sentinel lymph node) in people with early stomach cancer. The goal is to remove only the necessary lymph nodes, potentially reducing side effects while ensuring the cancer hasn't spread.
Changchun, JilinAges Any age - NCT07616310Recruiting
Removing vs. Cutting Ovarian Cancer from the Bowel
This study compares two surgical approaches for removing advanced ovarian cancer that has attached to the rectosigmoid (lower bowel). Both methods aim to remove the cancer safely, but this trial tests whether one approach works as well as the other.
Hangzhou, ZhejiangAges 18–70 - NCT07619391Recruiting
MyCap App: Tracking Treatment Time Burden in Pancreatic Cancer
This study asks pancreatic cancer patients to use a smartphone app called MyCap that tracks how much time their cancer treatment takes—like travel to appointments, time in the clinic, and side effects. Researchers want to understand the full burden of treatment to help doctors and future patients plan better.
Columbus, OhioAges 18 years+ - NCT07616440Recruiting
Ultrasound drug delivery with chemotherapy for HER2-positive breast cancer
This study tests a new technique that uses focused ultrasound to deliver cancer drugs directly to breast tumors, combined with standard chemotherapy. The goal is to improve treatment effectiveness for HER2-positive breast cancer before surgery.
Hangzhou, ZhejiangAges 18–70 - NCT07616297Recruiting
Higher Radiation Dose to Avoid Surgery in Rectal Cancer
This study tests whether giving a higher dose of radiation to rectal cancer tumors can help patients avoid surgery altogether. The goal is to shrink the tumor enough that surgery is no longer needed, preserving normal bowel function.
Rotterdam, South HollandAges 18 years+ - NCT07616427RecruitingPhase 2
New drug plus hormone therapy for HER2-positive breast cancer
This study tests a new drug called fovinaciclib combined with hormone therapy and HER2-targeting drugs for early-stage breast cancer that has specific markers (HR-positive and HER2-positive). The goal is to shrink tumors before surgery and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT07614061RecruitingPhase 1
Cell therapy for advanced bile duct cancer
This trial tests a new treatment called BTC-Ag-T, which uses your own immune cells enhanced in the lab to fight advanced biliary tract cancer (cancer of the bile ducts or gallbladder). It's designed for patients whose cancer has spread or cannot be surgically removed and who have already received standard chemotherapy plus immunotherapy.
ShanghaiAges 18 years+ - NCT07616453RecruitingPhase 2
New Drug Plus Hormone Therapy for Hormone-Responsive Breast Cancer
This trial tests whether a new drug called culmerciclib, combined with hormone therapy, works better than hormone therapy alone for early-stage breast cancer that grows quickly and responds to estrogen. The goal is to shrink tumors before surgery and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07617337RecruitingPhase 1
New drug for ALK-positive lung cancer
This trial tests a new oral medication called AQUA07 for people with a specific type of lung cancer (ALK-positive non-small cell lung cancer) that has grown or spread despite prior treatment with certain targeted drugs (ALK inhibitors). It aims to see if this new drug can control the cancer and be safe.
Houston, TexasAges 18 years+ - NCT07615101RecruitingPhase 3
PET scan imaging test for newly diagnosed prostate cancer
This study tests a new imaging agent (68Ga-NYM032) used with PET/CT scans to help doctors better detect prostate cancer before surgery. If you have biopsy-confirmed prostate cancer and are planning to have your prostate removed, this trial may help evaluate whether this new imaging method improves cancer detection.
Nanjing, JiangsuAges 18 years+ - NCT07617753RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Recurrent Ovarian Cancer
This trial tests a new type of cell therapy using modified natural killer cells (CAR-NK cells) that are trained to attack ovarian cancer cells. It's designed for patients whose cancer has come back or stopped responding to previous treatments.
Shenzhen, GuangdongAges 18–75 - NCT06706713RecruitingPhase 2
Testing BEBT-109 for advanced EGFR exon 20 lung cancer
This trial tests an experimental pill called BEBT-109 for people with a specific type of lung cancer (EGFR exon 20 insertion mutation) that has gotten worse after chemotherapy. The study aims to see if this targeted therapy can shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18 years+ - NCT05529940RecruitingPhase 3
FOLFIRINOX around surgery for resectable pancreatic cancer
This trial compares giving chemotherapy with FOLFIRINOX before and after surgery versus giving it mainly after surgery for people with resectable pancreatic duct cancer. It aims to improve outcomes by timing the treatment around the operation.
SeoulAges 19–80 - NCT05891561RecruitingPhase 2
Short antibody treatment after surgery for early HER2+ breast cancer
This Phase 2 study tests a shorter schedule of trastuzumab and pertuzumab combined with chemotherapy (taxanes) to reduce breast cancer coming back after surgery. It mainly helps people with early-stage, HER2-positive breast cancer that has not spread, by testing whether a shorter plan still works well and is tolerable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06708858RecruitingPhase 2
Studying surufatinib with chemo and immunotherapy for advanced bile duct cancer
This trial tests a combination of a targeted therapy (surufatinib), chemotherapy (gemcitabine and cisplatin), and an immunotherapy (durvalumab or pembrolizumab) for people with advanced bile duct cancer that hasn't been treated with systemic therapy before. The goal is to see if this combination can shrink tumors and improve outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT06706973Recruiting
Epigenetic study for new head and neck cancer treatments
This trial studies the role of epigenetic marks in head and neck cancer to improve diagnosis and treatment. If you have been newly diagnosed with head and neck squamous cell carcinoma and have not yet received treatment, you may be eligible to participate.
Milan, MIAges 18 years+ - NCT06706921RecruitingPhase 4
Predicting treatment success with PET scans in prostate cancer
This study looks at whether a special PET scan can help predict how well a targeted radiation therapy (LuPSMA) works in men with advanced prostate cancer that has spread. You would get several PET scans before and after treatment to see if the scan results can forecast your outcome.
Los Angeles, CaliforniaAges 18 years+ - NCT05440149RecruitingPhase 3
Radiation after surgery for certain node-positive breast cancer
This study tests whether giving radiation after breast surgery can improve outcomes for people with breast cancer that has spread to nearby lymph nodes (N1). You may be a candidate if you’ve already had surgery and meet specific details about your lymph nodes and cancer type.
Seoul, Jongro-guAges 19 years+ - NCT06451029Recruiting
Preventing diseases caused by smoking
This study is looking at ways to prevent smoking-related diseases. It enrolls long-term smokers who are age 50 or older and who are not planning to quit.
Milan, Italy, MilanAges 50 years+ - NCT06709326Recruiting
Collecting blood cells to study prostate cancer
This study uses a blood filtering procedure (apheresis) to collect prostate cancer cells from your blood for detailed analysis. It may help researchers understand why some prostate cancers spread, which could lead to better treatments. There are three groups: men with metastatic prostate cancer, men with PSA relapse after prostatectomy, and healthy volunteers.
Umeå, Norrlands University HospitalAges 18–81 - NCT07605962RecruitingPhase 1/Phase 2
UI-102 treatment for advanced cancer
This early-stage trial tests a new drug called UI-102 in people with advanced cancer. Researchers want to see if it is safe and whether it can help shrink tumors in patients who have already tried standard treatments.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,114 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.